Search Results - "Moon, Hyungseok C"
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Neuronal messenger ribonucleoprotein transport follows an aging Lévy walk
Published in Nature communications (24-01-2018)“…Localization of messenger ribonucleoproteins (mRNPs) plays an essential role in the regulation of gene expression for long-term memory formation and neuronal…”
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2
Optogenetic control of mRNA condensation reveals an intimate link between condensate material properties and functions
Published in Nature communications (15-04-2024)“…Biomolecular condensates, often assembled through phase transition mechanisms, play key roles in organizing diverse cellular activities. The material…”
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3
Aicardi-Goutières syndrome-associated gene SAMHD1 preserves genome integrity by preventing R-loop formation at transcription-replication conflict regions
Published in PLoS genetics (15-04-2021)“…The comorbid association of autoimmune diseases with cancers has been a major obstacle to successful anti-cancer treatment. Cancer survival rate decreases…”
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4
Real-time visualization of mRNA synthesis during memory formation in live mice
Published in Proceedings of the National Academy of Sciences - PNAS (05-07-2022)“…Memories are thought to be encoded in populations of neurons called memory trace or engram cells. However, little is known about the dynamics of these cells…”
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A transgenic mouse for imaging activity-dependent dynamics of endogenous Arc mRNA in live neurons
Published in Science advances (01-06-2018)“…Localized translation plays a crucial role in synaptic plasticity and memory consolidation. However, it has not been possible to follow the dynamics of…”
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6
L1 retrotransposons exploit RNA m6A modification as an evolutionary driving force
Published in Nature communications (09-02-2021)“…L1 retrotransposons can pose a threat to genome integrity. The host has evolved to restrict L1 replication. However, mechanisms underlying L1 propagation out…”
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7
Decoding Arc transcription: a live-cell study of stimulation patterns and transcriptional output
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-08-2024)“…Activity-regulated cytoskeleton-associated protein (Arc) plays a crucial role in synaptic plasticity, a process integral to learning and memory. Arc…”
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Live-cell imaging of single mRNA dynamics using split superfolder green fluorescent proteins with minimal background
Published in RNA (Cambridge) (01-01-2020)“…The MS2 system, with an MS2 binding site (MBS) and an MS2 coat protein fused to a fluorescent protein (MCP-FP), has been widely used to fluorescently label…”
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9
Intracellular gallium nitride microrod laser
Published in NPG Asia materials (02-04-2021)“…We report laser emission from gallium nitride (GaN) microrods that are introduced into mammalian cells and the application of these microrods for cell…”
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10
Real-Time Imaging of Transcription and Transport of Single Arc mRNA in Live Neurons
Published in Biophysical journal (07-02-2020)Get full text
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11
L1 retrotransposons exploit RNA m 6 A modification as an evolutionary driving force
Published in Nature communications (09-02-2021)“…L1 retrotransposons can pose a threat to genome integrity. The host has evolved to restrict L1 replication. However, mechanisms underlying L1 propagation out…”
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12
Formation of Arc mRNA granules in P-bodies
Published in IBRO reports (01-09-2019)Get full text
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