Search Results - "Moon, Haisle"

Surface Engineering for Cell-Based Therapies: Techniques for Manipulating Mammalian Cell Surfaces by Abbina, Srinivas, Siren, Erika M. J, Moon, Haisle, Kizhakkedathu, Jayachandran N

“…The introduction of cell-based therapies has provided new and unique strategies to treat many diseases and disorders including the recent approval of CAR-T…”
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An enzymatic pathway in the human gut microbiome that converts A to universal O type blood by Rahfeld, Peter, Sim, Lyann, Moon, Haisle, Constantinescu, Iren, Morgan-Lang, Connor, Hallam, Steven J., Kizhakkedathu, Jayachandran N., Withers, Stephen G.

“…Access to efficient enzymes that can convert A and B type red blood cells to ‘universal’ donor O would greatly increase the supply of blood for transfusions…”
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Prevention of vascular-allograft rejection by protecting the endothelial glycocalyx with immunosuppressive polymers by Siren, Erika M. J., Luo, Haiming D., Tam, Franklin, Montgomery, Ashani, Enns, Winnie, Moon, Haisle, Sim, Lyann, Rey, Kevin, Guan, Qiunong, Wang, Jiao-Jing, Wardell, Christine M., Monajemi, Mahdis, Mojibian, Majid, Levings, Megan K., Zhang, Zheng J., Du, Caigan, Withers, Stephen G., Choy, Jonathan C., Kizhakkedathu, Jayachandran N.

“…Systemic immunosuppression for the mitigation of immune rejection after organ transplantation causes adverse side effects and constrains the long-term benefits…”
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Investigation on Adaptability and Applicability of Polymer-Mediated Cell Surface Engineering by Ligation with Transglutaminase by Luo, Haiming D., Moon, Haisle, Siren, Erika, Clark, Meredith, Drayton, Matthew, Kizhakkedathu, Jayachandran N.

“…Polymer-mediated cell surface engineering can be a powerful tool to modify the cell’s biological behavior, but a simple ligation strategy must be identified…”
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Immunological Compatibility of Novel Enzyme-Converted Universal Blood Donor Cells by Moon, Haisle, Rahfeld, Peter, Constantinescu, Iren, Drayton, Matthew, Devine, Dana V., Withers, Stephen G, Kizhakkedathu, Jayachandran N

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Ultrahigh-Throughput Single Emulsion Droplet Screening for the Discovery of New B Antigen Cleaving Enzymes by Olagnon, Charlotte, Wardman, Jacob F., Liu, Feng, Chen, Hong-Ming, Moon, Haisle, Nasseri, Seyed A., Seale, Dan, Rahfeld, Peter, Hallam, Steven J., Kizhakkedathu, Jayachandran N., Withers, Stephen G.

“…In search of efficient α-galactosidases that can convert B red blood cells (RBCs) to universal type RBCs, we have developed a simple and robust system for…”
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An Ultrahydrating Polymer that Protects Protein Therapeutics and RNA‐Lipid Nanoparticles Against Freezing, Heat and Lyophilization Stress by Herrmann, Anna, Abbina, Srinivas, Bathula, Nuthan Vikas, Nouri, Peyman Malek Mohammadi, Chafeeva, Irina, Constantinescu, Iren, Abbasi, Emaan, Abbasi, Usama, Drayton, Matthew, Luo, Haiming Daniel, Moon, Haisle, Gill, Arshdeep, Xi, Yu, Bertram, Allan K., Du, Caigan, Haag, Rainer, Blakney, Anna K., Kizhakkedathu, Jayachandran N.

“…RNA and protein‐based therapeutics constitute almost half of recent drug approvals and receive considerable attention within biotechnology industries. Ensuring…”
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Biomimetically Mineralized Alginate Nanocomposite Fibers for Bone Tissue Engineering: Mechanical Properties and in Vitro Cellular Interactions by Chae, Taesik, Yang, Heejae, Moon, Haisle, Troczynski, Tom, Ko, Frank K

“…We report herein the structural and mechanical properties and in vitro cellular response of hydroxyapatite (HAp)/alginate nanocomposite fibrous scaffolds…”
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Novel grooved substrata stimulate macrophage fusion, CCL2 and MMP-9 secretion by Moon, Haisle, Cremmel, Clément V. M., Kulpa, Alina, Jaeger, Nicolas A. F., Kappelhoff, Reinhild, Overall, Christopher M., Waterfield, J. Douglas, Brunette, Donald M.

“…Rough surface topographies on implants attract macrophages but the influence of topography on macrophage fusion to produce multinucleated giant cells (MGC) and…”
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