Search Results - "Moon, Ae Ran"

Minimal killing unit of the mitochondrial targeting domain of Noxa by Kim, Ji-Young, Han, Ji Hye, Moon, Ae-Ran, Park, Jung Hee, Chang, Jeong Hwan, Bae, Jeehyeon, Kim, Tae-Hyoung

“…Noxa is a key player in p53‐induced cell death via mitochondrial dysfunction, and the mitochondrial‐targeting domain (MTD) of Noxa is responsible for the…”
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Potentiation of TRAIL killing activity by multimerization through isoleucine zipper hexamerization motif by Han, Ji Hye, Moon, Ae Ran, Chang, Jeong Hwan, Bae, Jeehyeon, Choi, Jin Myung, Lee, Sung Haeng, Kim, Tae-Hyoung

“…Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a homo-trimeric cytotoxic ligand. Several studies have demonstrated that incorporation…”
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DUSP6 is a novel transcriptional target of p53 and regulates p53-mediated apoptosis by modulating expression levels of Bcl-2 family proteins by Piya, Sujan, Kim, Ji Young, Bae, Jeehyeon, Seol, Dai-Wu, Moon, Ae Ran, Kim, Tae-Hyoung

“…► p53 transactivates dual specificity phosphatase 6 (DUSP6) to regulate ERK1/2. ► Knock-down of DUSP6 expression inhibits p53-mediated cell death. ►…”
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The regulation of combined treatment-induced cell death with recombinant TRAIL and bortezomib through TRAIL signaling in TRAIL-resistant cells by Ryu, Sunhyo, Ahn, Yun Jeong, Yoon, Chakeong, Chang, Jeong Hwan, Park, Yoonkyung, Kim, Tae-Hyoung, Howland, Amanda R, Armstrong, Cheryl A, Song, Peter I, Moon, Ae Ran

“…Multiple trials have attempted to demonstrate the effective induction of cell death in TRAIL-resistant cancer cells, including using a combined treatment of…”
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MUDENG is cleaved by caspase-3 during TRAIL-induced cell death by Shin, Jin Na, Han, Ji Hye, Kim, Ji-Young, Moon, Ae-Ran, Kim, Ji Eun, Chang, Jeong Hwan, Bae, Jeehyeon, Oh, Jae Wook, Kim, Tae-Hyoung

“…•MUDENG is cleaved by caspase-3.•The cleavage of MUDENG is an early event of TRAIL-induced cell death.•MUDENG cleavage results in reduction of cell death…”
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Necrosis-inducing peptide has the beneficial effect on killing tumor cells through neuropilin (NRP-1) targeting by Kim, Ji-Young, Han, Ji-Hae, Park, Geon, Seo, Young-Woo, Yun, Cheol-Won, Lee, Byung-Chul, Bae, Jeehyeon, Moon, Ae Ran, Kim, Tae-Hyoung

“…The therapeutic efficacy of most anti-cancer drugs depends on their apoptosis-inducing abilities. Previously, we showed that a peptide containing the…”
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DOBI is cleaved by caspases during TRAIL-induced apoptotic cell death by Park, Sun-Young, Shin, Jin-Na, Woo, Ha-Na, Piya, Su-Jan, Moon, Ae-Ran, Seo, Young-Woo, Seol, Dai-Wu, Kim, Tae-Hyoung

“…Downstream of Bid (DOBI) known as Pus10, has been identified as a modulator of TRAIL-induced cell death using RNAi library screening. The crystal structure of…”
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Transcription Factors NF-YA Regulate the Induction of Human OGG1 Following DNA-alkylating Agent Methylmethane Sulfonate (MMS) Treatment by Lee, Mi-Rha, Kim, Soo-Hyun, Cho, Hyun-Ju, Lee, Kun-Yeong, Moon, Ae Ran, Jeong, Hye Gwang, Lee, Jung-Sup, Hyun, Jin-Won, Chung, Myung-Hee, You, Ho Jin

“…A human 8-oxoguanine-DNA glycosylase (hOGG1) is the main enzyme that repairs 8-oxoG, which is a critical mutagenic lesion. There is a great deal of interest in…”
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DOBI is cleaved by caspases during TRAIL-induced apoptotic cell death by Park, S.Y. (Chosun University School of Medicine, Gwangju, Republic of Korea), Shin, J.N. (Chosun University School of Medicine, Gwangju, Republic of Korea), Woo, H.N. (Chosun University School of Medicine, Gwangju, Republic of Korea), Piya, Sujan (Chosun University School of Medicine, Gwangju, Republic of Korea), Moon, A.R. (Chosun University School of Medicine, Gwangju, Republic of Korea), Seo, Y.W. (Chonnam National University, Gwangju, Republic of Korea), Seol, D.W. (Kyungwon University, Sungnam, Republic of Korea), Kim, T.H. (Chosun University School of Medicine, Gwangju, Republic of Korea), E-mail: thkim65@mail.chosun.ac.kr

“…Downstream of Bid (DOBI) known as Pus10, has been identified as a modulator of TRAIL-induced cell death using RNAi library screening. The crystal structure of…”
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Inverse regulation of serum osteoprotegerin and tumor necrosis factor-related apoptosis-inducing ligand levels in patients with leg lesional vascular calcification: An observational study by Moon, Ae Ran, Park, Yoonkyung, Chang, Jeong Hwan, Lee, Sang Su

“…We hypothesized that circulating osteoprotegerin (OPG) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) levels could be associated with…”
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Correction: Necrosis-inducing peptide has the beneficial effect on killing tumor cells through neuropilin (NRP-1) targeting by Kim, Ji-Young, Han, Ji-Hae, Park, Geon, Seo, Young-Woo, Yun, Cheol-Won, Lee, Byung-Chul, Bae, Jeehyeon, Moon, Ae Ran, Kim, Tae-Hyoung

“…[This corrects the article DOI: 10.18632/oncotarget.8719.]…”
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Potentiation of TRAIL killing activity by multimerization through isoleucine zipper hexamerization motif by Han, Ji Hye, Moon, Ae Ran, Chang, Jeong Hwan, Bae, Jeehyeon, Choi, Jin Myung, Lee, Sung Haeng, Kim, Tae-Hyoung

“…Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a homo-trimeric cytotoxic ligand. Several studies have demonstrated that incorporation…”
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High-sensitivity C-reactive protein and mean platelet volume as predictive values after percutaneous coronary intervention for long-term clinical outcomes: a comparable and additive study by Moon, Ae Ran, Choi, Dong-Hyun, Jahng, Su-Young, Kim, Bo-Bae, Seo, Hong-Joo, Kim, Sang Hun, Ryu, Sang-Wan, Song, Heesang, Kim, Tae-Hyoung

“…This study was designed to establish the relationship of high-sensitivity C-reactive protein (hsCRP) and mean platelet volume (MPV) with the development of…”
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Suppression of IRF4 by IRF1, 3, and 7 in Noxa expression is a necessary event for IFN-γ-mediated tumor elimination by Piya, Sujan, Moon, Ae Ran, Song, Peter I, Hiscott, John, Lin, Rongtuan, Seol, Dai-Wu, Kim, Tae-Hyoung

“…IFN-γ plays a critical role in tumor immunosurveillance by affecting either immune cells or tumor cells; however, IFN-mediated effects on tumor elimination are…”
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The cell death-inducing activity of the peptide containing Noxa mitochondrial-targeting domain is associated with calcium release by Seo, Young-Woo, Woo, Ha-Na, Piya, Sujan, Moon, Ae Ran, Oh, Jae-Wook, Yun, Cheol-Won, Kim, Kyung-Keun, Min, Ji-Young, Jeong, Seon-Yong, Chung, Seyung, Song, Peter I, Jeong, Seong-Yun, Choi, Eun Kyung, Seol, Dai-Wu, Kim, Tae-Hyoung

“…DNA damage stabilizes the p53 tumor suppressor protein that determines the cell fate by either cell cycle arrest or cell death induction. Noxa, the BH3-only…”
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Effects of the BH3-only protein human Noxa on mitochondrial dynamics by Woo, Ha-Na, Seo, Young-Woo, Moon, Ae Ran, Jeong, Seon-Yong, Jeong, Seong-Yun, Choi, Eun Kyung, Kim, Tae-Hyoung

“…Mitochondria form reticular networks comprised of filamentous tubules and continuously move and change shape. Bcl-2 family proteins actively participate in the…”
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Therapeutic Inhibitors against Mutated BRAF and MEK for the Treatment of Metastatic Melanoma by Ryu, Sunhyo, Youn, Chakyung, Moon, Ae Ran, Howland, Amanda, Armstrong, Cheryl A, Song, Peter I

“…Melanoma is one of the most aggressive cancers in the world and is responsible for the majority of skin cancer deaths. Recent advances in the field of…”
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Homer1 regulates the susceptibility to TRAIL by Shin, Jin Na, Piya, Sujan, Yun, Cheol-Won, Seol, Dai-Wu, Seo, Young-Woo, Moon, Ae Ran, Kim, Tae-Hyoung

“…TRAIL is an apoptotic cell death-inducing ligand that belongs to a TNF superfamily. To identify the regulators that govern the susceptibility to TRAIL,…”
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Protective effect of metallothionein-III on DNA damage in response to reactive oxygen species by You, Ho Jin, Oh, Deuk-hee, Choi, Chul Yung, Lee, Dong Gun, Hahm, Kyung-Soo, Moon, Ae Ran, Jeong, Hye Gwang

“…Metallothionein (MT)-III is a member of a brain-specific MT family, in contrast to MT-I and MT-II that are found in most tissues and are implicated in metal…”
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A novel protein, MUDENG, induces cell death in cytotoxic T cells by Lee, Mi-Rha, Shin, Jin Na, Moon, Ae Ran, Park, Sun-Young, Hong, Gilsun, Lee, Mi-Ja, Yun, Cheol-won, Seol, Dai-Wu, Piya, Sujan, Bae, Jeehyeon, Oh, Jae-Wook, Kim, Tae-Hyoung

“…A screening system comprised of a randomized hybrid-ribozyme library has previously been used to identify pro-death genes in Fas-mediated apoptosis, and short…”
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