Search Results - "Moomaw, Carolyn R."

Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody by Ramsland, Paul A, Terzyan, Simon S, Cloud, Gwendolyn, Bourne, Christina R, Farrugia, William, Tribbick, Gordon, Geysen, H Mario, Moomaw, Carolyn R, Slaughter, Clive A, Edmundson, Allen B

“…The 2.6 A (1 A=0.1 nm) resolution structure has been determined for the glycosylated Fab (fragment antigen binding) of an IgM (Yvo) obtained from a subject…”
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ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity by Brown, H A, Gutowski, S, Moomaw, C R, Slaughter, C, Sternweis, P C

“…The hydrolysis of phosphatidylcholine by phospholipase D (PLD) results in the production of phosphatidic acid and choline. An assay that uses an exogenous…”
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The 21- and 23-kD forms of TCRζ are generated by specific ITAM phosphorylations by van Oers, Nicolai S. C, Tohlen, Brett, Malissen, Bernard, Moomaw, Carolyn R, Afendis, Steve, Slaughter, Clive A

“…The T cell receptor (TCR) zeta subunit contains three immunoreceptor tyrosine-based activation motifs (ITAMs) that translate effective extracellular ligand…”
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Identification, Purification, and Characterization of a PA700-dependent Activator of the Proteasome (∗) by DeMartino, George N., Proske, Rita J., Moomaw, Carolyn R., Strong, Anita A., Song, Xiaoling, Hisamatsu, Hiroshi, Tanaka, Keiji, Slaughter, Clive A.

“…The activity of the intracellular protease, the proteasome, is modulated by a number of specific regulatory proteins. One such regulator, PA700, is a…”
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Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties by Bourne, Philip C., Ramsland, Paul A., Shan, Lin, Fan, Zhao-C., DeWitt, Christina R., Shultz, Brandon B., Terzyan, Simon S., Moomaw, Carolyn R., Slaughter, Clive A., Guddat, Luke W., Edmundson, Allen B.

“…The X‐ray structure of an immunoglobulin light‐chain dimer isolated from the urine as a `Bence‐Jones protein' from a patient with multiple myeloma and…”
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Proteolytic Cleavage of the Fe−S Subunit Hinge Region of Rhodobacter capsulatus bc 1 Complex:  Effects of Inhibitors and Mutations by Valkova-Valchanova, Maria, Darrouzet, Elisabeth, Moomaw, Carolyn R, Slaughter, Clive A, Daldal, Fevzi

“…The three-dimensional structure of the mitochondrial bc 1 complex reveals that the extrinsic domain of the Fe−S subunit, which carries the redox-active [2Fe2S]…”
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Degradation of oxidized insulin B chain by the multiproteinase complex macropain (proteasome) by Dick, Lawrence R, Moomaw, Carolyn R, DeMartino, George N, Slaughter, Clive A

“…The peptides generated from the degradation of the oxidized B chain of bovine insulin by the multiproteinase complex macropain (proteasome) have been analyzed…”
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Identification of a Cysteine Residue Essential for Activity of Protein Farnesyltransferase by Fu, Hua-Wen, Moomaw, John F., Moomaw, Carolyn R., Casey, Patrick J.

“…Protein farnesyltransferase (FTase) is a zinc metalloenzyme that performs a post-translational modification on many proteins that is critical for their…”
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Expression and characterization of recombinant human acyloxyacyl hydrolase, a leukocyte enzyme that deacylates bacterial lipopolysaccharides by Hagen, Frederick S, Grant, Francis J, Kuijper, Joseph L, Slaughter, Clive A, Moomaw, Carolyn R, Orth, Kim, O'Hara, Patrick J, Munford, Robert S

“…The molecular cloning and eukaryotic cell expression of the complementary DNA for human neutrophil acyloxyacyl hydrolase (AOAH) are described. AOAH is a…”
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Comparison of the soluble and membrane-bound forms of the puromycin-sensitive enkephalin-degrading aminopeptidases from rat by Dyer, S H, Slaughter, C A, Orth, K, Moomaw, C R, Hersh, L B

“…Enkephalin degradation in brain has been shown to be catalyzed, in part, by a membrane-bound puromycin-sensitive aminopeptidase. A cytosolic…”
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Identification and localization of a cysteinyl residue critical for the trypsin-like catalytic activity of the proteasome by Dick, Lawrence R, Moomaw, Carolyn R, Pramanik, Bikash C, DeMartino, George N, Slaughter, Clive A

“…Chemical modification of the proteasome with N-ethylmaleimide (NEM) was performed for the purpose of identifying amino acid residues that play a role in the…”
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Molecular Cloning of the Mature NAD+-dependent Succinic Semialdehyde Dehydrogenase from Rat and Human by Chambliss, Ken L., Caudle, Deborah L., Hinson, Debra D., Moomaw, Carolyn R., Slaughter, Clive A., Jakobs, Cornelis, Gibson, K. Michael

“…Three rat brain cDNA clones ~3500, 1465, and 1135 base pairs in length encoding succinic semialdehyde dehydrogenase (SSADH; EC 1.2.1.24) were isolated from two…”
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Azotobacter vinelandii Citrate Synthase by Rault-Leonardon, Magali, Atkinson, Mark A. L, Slaughter, Clive A, Moomaw, Carolyn R, Srere, Paul A

“…We have purified the citrate synthase from Azotobacter vinelandii and have determined that the size of the subunit is 48000 Da and the structure of the…”
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Proteolytic Cleavage of the Fe−S Subunit Hinge Region of Rhodobacter capsulatus bc1 Complex:  Effects of Inhibitors and Mutations by VALKOVA-VALCHANOVA, Maria, DARROUZET, Elisabeth, MOOMAW, Carolyn R., SLAUGHTER, Clive A., DALDAL, Fevzi

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PA700, an ATP-dependent activator of the 20 S proteasome, is an ATPase containing multiple members of a nucleotide-binding protein family by DEMARTINO, G. N, MOOMAW, C. R, ZAGNITKO, O. P, PROSKE, R. J, MA CHU-PING, AFENDIS, S. J, SWAFFIELD, J. C, SLAUGHTER, C. A

“…PA700 is a 700,000-dalton multisubunit protein that activates multiple proteolytic activities of the 20 S proteasome by a mechanism dependent upon ATP…”
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Proteolytic processing of ovalbumin and beta-galactosidase by the proteasome to a yield antigenic peptides by Dick, LR, Aldrich, C, Jameson, SC, Moomaw, CR, Pramanik, BC, Doyle, CK, DeMartino, GN, Bevan, MJ, Forman, JM, Slaughter, CA

“…The identification of genes in the class II region of the MHC that are homologous to genes encoding subunits of the proteasome has led to intense interest in…”
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Characterization of δ-Sarcoglycan, a Novel Component of the Oligomeric Sarcoglycan Complex Involved in Limb-Girdle Muscular Dystrophy by Jung, Daniel, Duclos, Franck, Apostol, Barbara, Straub, Volker, Lee, Jane C., Allamand, Valérie, Venzke, David P., Sunada, Yoshihide, Moomaw, Carolyn R., Leveille, Cynthia J., Slaughter, Clive A., Crawford, Thomas O., McPherson, John D., Campbell, Kevin P.

“…The sarcoglycan complex is known to be involved in limb-girdle muscular dystrophy (LGMD) and is composed of at least three proteins: α-, β-, and γ-sarcoglycan…”
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Primary structure and topological analysis of a skeletal muscle-specific junctional sarcoplasmic reticulum glycoprotein (triadin) by KNUDSON, C. M, STANG, K. K, MOOMAW, C. R, SLAUGHTER, C. A, CAMPBELL, K. P

“…The primary amino acid sequence for a highly abundant junctional sarcoplasmic reticulum glycoprotein (triadin) has been deduced from the cDNA sequence. Based…”
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Heterogeneity of the 59-kDa dystrophin-associated protein revealed by cDNA cloning and expression by BIN YANG, IBRAGHIMOV-BESKROVNAYA, O, MOOMAW, C. R, SLAUGHTER, C. A, CAMPBELL, K. P

“…The 59-kDa dystrophin-associated protein triplet (59-DAP) is a component of the dystrophin-glycoprotein complex which may directly associate with dystrophin…”
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Molecular cloning of the mature NAD(+)-dependent succinic semialdehyde dehydrogenase from rat and human. cDNA isolation, evolutionary homology, and tissue expression by Chambliss, K L, Caudle, D L, Hinson, D D, Moomaw, C R, Slaughter, C A, Jakobs, C, Gibson, K M

“…Three rat brain cDNA clones approximately 3500, 1465, and 1135 base pairs in length encoding succinic semialdehyde dehydrogenase (SSADH; EC 1.2.1.24) were…”
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