Search Results - "Moola Joghee, Nanjan"

Virtual high throughput screening: Potential inhibitors for SARS-CoV-2 PLPRO and 3CLPRO proteases by Jade, Dhananjay, Ayyamperumal, Selvaraj, Tallapaneni, Vyshnavi, Joghee Nanjan, Chandrasekar Moola, Barge, Sagar, Mohan, Surender, Nanjan, Moola Joghee

“…The pandemic, COVID-19, has spread worldwide and affected millions of people. There is an urgent need, therefore, to find a proper treatment for the novel…”
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Positive allosteric activation of glial EAAT-2 transporter protein: A novel strategy for Alzheimer’s disease by Manisha, Chennu, Selvaraj, Ayyamperumal, Jubie, Selvaraj, Moola Joghee Nanjan, Chandrasekar, Moola Joghee, Nanjan, Clement, James Premdoss, Justin, Antony

“…Excitatory amino acid transporter-2 (EAAT-2) protein localized in the membrane of glial cells are responsible for the clearance of glutamate in synapse and it…”
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Plant-based Natural Products for Wound Healing: A Critical Review by Ramalingam, Shalini, Chandrasekar, Moola Joghee Nanjan, Nanjan, Moola Joghee

“…Wound healing is an intricate process consisting of four overlapping phases, namely hemostasis, inflammation, proliferation, and remodelling. Effective…”
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Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus by Bhatt, Jayesh Kumar, Thomas, Sabin, Nanjan, Moola Joghee

“…Abstract Resveratrol is a naturally occurring polyphenolic compound. Numerous animal studies have been reported on its wide-ranging beneficial effects in the…”
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1-Tetracosanol isolated from the leaves of Eupatorium glandulosum, accelerates wound healing by expressing inflammatory cytokines and matrix metalloproteinase by Shalini, Ramalingam, Chandrasekar, Moola Joghee Nanjan, Nanjan, Moola Joghee, Madhunapantula, SubbaRao V., Karnik, Medha, Selvaraj, Jubi, Ganesh, Gonna Nandhi Krishnan

“…The leave paste of the plant, Eupatorium glandulosum H. B & K, has been traditionally used to treat cuts and wounds by the tribal community of the Nilgiris…”
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Structural and functional analysis of Chitinase-IV of Brassica juncea: molecular modeling and dynamic simulation study by Ayyamperumal, Selvaraj, Jade, Dhananjay, Tallapaneni, Vyshnavi, Mohan, Surender, Barge, Sagar, Moola Joghee, Nanjan, M. J. N., Chandrasekar

“…Brassica juncea is an important oil seed crop. The productivity of this plant, however, is known to be low due to the attack of plant pathogens. The plant…”
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Phyllanthus maderaspatensis, a dietary supplement for the amelioration of adriamycin-induced toxicity and oxidative stress in mice by Bommu, Praveen, Nanjan, Chandrasekar Moola Joghee, Joghee, Nanjan Moola, Nataraj, Satishkumar Muthureddy, Bhojraj, Suresh

“…The effect of ethanol extract of Phyllanthus maderaspatensis (PME), a popular south Indian dietary supplement, was studied for its chemoprotective property on…”
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Synthesis and Characterization of Dipeptide–Drug Conjugate: The Use of Linker Coupling Reaction by Ramamurthi, Deepthi, Selvaraj, Jubie, Patnaik, Sunil Kumar, Palathoti, Nagarjuna, Rajeshkumar, Raman, Chandrasekar, Moola Joghee Nanjan

“…Most of the effective anticancer drugs available in the market suffer from adverse effects due to their lack of target specificity. Therefore, so many delivery…”
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Potential inhibitors for FKBP51: an in silico study using virtual screening, molecular docking and molecular dynamics simulation by Barge, Sagar, Jade, Dhananjay, Ayyamperumal, Selvaraj, Manna, Prasenjit, Borah, Jagat, Nanjan, Chandrasekar Moola Joghee, Nanjan, Moola Joghee, Talukdar, Narayan Chandra

“…Over the years, FK506-binding proteins have been targeted for different pharmaceutical interests. The FK506-binding protein, encoded by the FKBP5 gene, is…”
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Virtual high throughput screening: Potential inhibitors for SARS-CoV-2 PL PRO and 3CL PRO proteases by Jade, Dhananjay, Ayyamperumal, Selvaraj, Tallapaneni, Vyshnavi, Joghee Nanjan, Chandrasekar Moola, Barge, Sagar, Mohan, Surender, Nanjan, Moola Joghee

“…The pandemic, COVID-19, has spread worldwide and affected millions of people. There is an urgent need, therefore, to find a proper treatment for the novel…”
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An in vitro-in vivo correlation study of modified release formulations of Venlafaxine.HCl by J.R. Aravindaraj, D. Manikandan, Moola Joghee Nanjan

“…A single dose, randomized, complete and four treatment cross over study was conducted in healthy human subjects for IVIVC of venlafaxine.HCl. Plasma…”
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Elastin-like polypeptides and their applications in anticancer drug delivery systems: a review by Saxena, Rubha, Nanjan, Moola Joghee

“…Elastin-like polypeptides (ELPs) are large molecular weight biopolymers. They have been widely studied as macromolecular carriers for targeted delivery of…”
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Repurposing of FDA Approved Drugs and Neuropep peptides as Anticancer Agents Against ErbB1 and ErbB2 by Patnaik, Sunil Kumar, Swaroop, Akey Krishna, Naik, Mudavath Ravi, Selvaraj, Jubie, Chandrasekar, Moola Joghee Nanjan

“…ErbB1 and ErbB2 are the most important biological targets in cancer drug discovery and development of dual inhibitors for the cancer therapy. FDA approved…”
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Crystallographic and computational investigations of structural properties in phenyl and methoxy‑phenyl substituted 1,4 dihydropyridine derivatives by Ethiraj, Jayashree, Ajin, R., Sankaranarayanan, R.K., Sekar, Ranjith, Veeman, Dhinakaran, Nanjan, Moola Joghee, Varghese, Jithin John

“…•Crystal structures of two new 1,4-DHP derivatives labelled as M1 and M2 are reported.•Hirshfeld surface analysis revealed the dominant HH interactions in the…”
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A combination of resveratrol and 3,3'-diindolylmethane, a potent radioprotector by Thekkekkara, Dithu, Basavan, Duraiswamy, Chandna, Sudhir, Nanjan, Moola Joghee

“…Exposure to ionizing radiation causes damage to the genomic integrity and stability of the cell. Though a large number of molecules have been studied for their…”
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Structural investigations of halogen substituted 1,4-dihydropyridine derivatives: Crystallographic and computational studies by Ethiraj, Jayashree, Sekar, Ranjith, Shankar, Bhaskaran, Nanjan, Moola Joghee, Sankaranarayanan, R.K., Vu, Khanh B.

“…•Two new crystal structures of 1,4-DHP derivatives labelled as M-Cl and M-F are reported.•Hirsh field surface analysis revealed the intermolecular contacts%…”
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Downregulation of NT5C3 gene expressions by elastin-like polypeptide gemcitabine conjugate for ovarian cancer therapy by Ramamurthi, Deepthi, Selvaraj, Jubie, Raj, P. Vasanth, Tallapaneni, Vyshnavi, Chandrasekar, Moola Joghee Nanjan

“…Due to the undesirable side effects and lack of target specificity of existing anticancer drugs the newer drug delivery system with target specificity and…”
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Resveratrol for the Management of Diabetes and its Downstream Pathologies by Nanjan, Moola Joghee, Betz, James

“…Over the past 10 years more than 10,000 papers and investigations have been published that identify or analyse various critical pathways and biological…”
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Molecular docking analysis of α-Topoisomerase II with δ-Carboline derivatives as potential anticancer agents by Ayyamperumal, Selvaraj, Dj, Dhananjay, Tallapaneni, Vyshnavi, Mohan, Surender, S, Basappa, Selvaraj, Jubie, Joghee, Nanjan Moola, Mjn, Chandrasekar

“…The enzyme, α-topoisomerase II (α-Topo II), is known to regulate efficiently the topology of DNA. It is highly expressed in rapidly proliferating cells and…”
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An in vitro-in vivo correlation study of modified release formulations of Venlafaxine.HCl by Aravindaraj, J.R., Manikandan, D., Nanjan, Moola Joghee

“…A single dose, randomized, complete and four treatment cross over study was conducted in healthy human subjects for IVIVC of venlafaxine.HCl, Plasma…”
Get full text