Search Results - "Mooij, T.M"

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    ProteinCCD: enabling the design of protein truncation constructs for expression and crystallization experiments by Mooij, Wijnand T.M, Mitsiki, Eirini, Perrakis, Anastassis

    Published in Nucleic acids research (01-07-2009)
    “…ProteinCCD (CCD for Crystallographic Construct Design) aims to facilitate a common practice in structural biology, namely the design of several truncation…”
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    Increased risk for ovarian cancer and borderline ovarian tumours in subfertile women with endometriosis by Buis, C.C.M., van Leeuwen, F.E., Mooij, T.M., Burger, C.W.

    Published in Human reproduction (Oxford) (01-12-2013)
    “…STUDY QUESTION Is ovarian or extra-ovarian endometriosis associated with an increased risk of ovarian cancer and borderline ovarian tumours (BOT)? SUMMARY…”
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    Maternal death related to IVF in the Netherlands 1984–2008 by Braat, D.D.M., Schutte, J.M., Bernardus, R.E., Mooij, T.M., van Leeuwen, F.E.

    Published in Human reproduction (Oxford) (01-07-2010)
    “…BACKGROUND We assessed all deaths in the Netherlands that might have been related to IVF or to an IVF pregnancy in order to investigate this most serious…”
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    Melanoma risk after ovarian stimulation for in vitro fertilization by Spaan, M., van den Belt-Dusebout, A.W., Schaapveld, M., Mooij, T.M., Burger, C.W., van Leeuwen, F.E.

    Published in Human reproduction (Oxford) (01-05-2015)
    “…STUDY QUESTION Do women treated with ovarian stimulation for IVF have an increased risk of melanoma? SUMMARY ANSWER Ovarian stimulation for IVF does not…”
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    A reduced size of the ovarian follicle pool is associated with an increased risk of a trisomic pregnancy in IVF-treated women by Haadsma, M.L., Mooij, T.M., Groen, H., Burger, C.W., Lambalk, C.B., Broekmans, F.J.M., van Leeuwen, F.E., Bouman, K., Hoek, A.

    Published in Human reproduction (Oxford) (01-02-2010)
    “…BACKGROUND The increased risk of a trisomic pregnancy with a woman's age arises from an increased rate of meiotic non-disjunction in the oocytes. It has been…”
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    Factors associated with dizygotic twinning after IVF treatment with double embryo transfer by Groeneveld, E., Lambers, M.J., Stakelbeek, M.E.F., Mooij, T.M., van den Belt-Dusebout, A.W., Heymans, M.W., Schats, R., Hompes, P.G.A., Hoek, A., Burger, C.W., van Leeuwen, F.E., Lambalk, C.B.

    Published in Human reproduction (Oxford) (01-10-2012)
    “…BACKGROUND Dizygotic twin pregnancies after IVF treatment are the result of multiple embryos transferred into the uterine cavity, followed by successful double…”
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    Diverse, High-Quality Test Set for the Validation of Protein−Ligand Docking Performance by Hartshorn, Michael J, Verdonk, Marcel L, Chessari, Gianni, Brewerton, Suzanne C, Mooij, Wijnand T. M, Mortenson, Paul N, Murray, Christopher W

    Published in Journal of medicinal chemistry (22-02-2007)
    “…A procedure for analyzing and classifying publicly available crystal structures has been developed. It has been used to identify high-resolution protein−ligand…”
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    General and targeted statistical potentials for protein-ligand interactions by Mooij, Wijnand T. M., Verdonk, Marcel L.

    “…We present a novel atom–atom potential derived from a database of protein–ligand complexes. First, we clarify the similarities and differences between two…”
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    Virtual Screening Using Protein−Ligand Docking:  Avoiding Artificial Enrichment by Verdonk, Marcel L, Berdini, Valerio, Hartshorn, Michael J, Mooij, Wijnand T. M, Murray, Christopher W, Taylor, Richard D, Watson, Paul

    “…This study addresses a number of topical issues around the use of protein−ligand docking in virtual screening. We show that, for the validation of such…”
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    “Conditional Restraints”: Restraining the Free Atoms in ARP/wARP by Mooij, Wijnand T.M., Cohen, Serge X., Joosten, Krista, Murshudov, Garib N., Perrakis, Anastassis

    Published in Structure (London) (13-02-2009)
    “…The automated building of a protein model into an electron density map remains a challenging problem. In the ARP/wARP approach, model building is facilitated…”
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    Automated Protein-Ligand Crystallography for Structure-Based Drug Design by Mooij, Wijnand T. M., Hartshorn, Michael J., Tickle, Ian J., Sharff, Andrew J., Verdonk, Marcel L., Jhoti, Harren

    Published in ChemMedChem (01-08-2006)
    “…An approach to automate protein–ligand crystallography is presented, with the aim of increasing the number of structures available to structure‐based drug…”
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