Search Results - "Mooij, Hans L"
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The metabolism of triglyceride-rich lipoproteins revisited: New players, new insight
Published in Atherosclerosis (01-07-2010)“…Abstract Peripheral lipoprotein lipase (LPL)-mediated lipolysis of triglycerides is the first step in chylomicron/VLDL clearance involving heparan sulfate…”
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Measuring endothelial glycocalyx dimensions in humans: a potential novel tool to monitor vascular vulnerability
Published in Journal of applied physiology (1985) (01-03-2008)“…Departments of 1 Vascular Medicine and of 2 Physiology, Academic Medical Center, Amsterdam; and 3 Department of Physiology, Maastricht University, Maastricht,…”
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Endothelial Glycocalyx Damage Coincides With Microalbuminuria in Type 1 Diabetes
Published in Diabetes (New York, N.Y.) (01-04-2006)“…Endothelial Glycocalyx Damage Coincides With Microalbuminuria in Type 1 Diabetes Max Nieuwdorp 1 , Hans L. Mooij 1 , Jojanneke Kroon 1 , Bektas Atasever 2 ,…”
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Loss of Endothelial Glycocalyx During Acute Hyperglycemia Coincides With Endothelial Dysfunction and Coagulation Activation In Vivo
Published in Diabetes (New York, N.Y.) (01-02-2006)“…Loss of Endothelial Glycocalyx During Acute Hyperglycemia Coincides With Endothelial Dysfunction and Coagulation Activation In Vivo Max Nieuwdorp 1 , Timon W…”
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Endothelial glycocalyx as potential diagnostic and therapeutic target in cardiovascular disease
Published in Current opinion in lipidology (01-02-2009)“…The endothelial glycocalyx has emerged as a potential orchestrator of vascular homeostasis. Under physiological conditions, the glycocalyx is an important…”
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Rapid insulin-mediated increase in microvascular glycocalyx accessibility in skeletal muscle may contribute to insulin-mediated glucose disposal in rats
Published in PloS one (31-01-2013)“…It has been demonstrated that insulin-mediated recruitment of microvascular blood volume is associated with insulin sensitivity. We hypothesize that insulin…”
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Partial recovery of the endothelial glycocalyx upon rosuvastatin therapy in patients with heterozygous familial hypercholesterolemia
Published in Journal of lipid research (01-01-2009)“…The endothelial glycocalyx has been shown to serve as a protective barrier between the flowing blood and the vessel wall in experimental models. The aim of…”
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Carriers of loss-of-function mutations in EXT display impaired pancreatic beta-cell reserve due to smaller pancreas volume
Published in PloS one (26-12-2014)“…Exotosin (EXT) proteins are involved in the chain elongation step of heparan sulfate (HS) biosynthesis, which is intricately involved in organ development…”
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Nitrous oxide abuse leading to extreme homocysteine levels and thrombosis in young adults: a case series
Published in Journal of thrombosis and haemostasis (01-02-2023)“…Neurologic complications from recreational use of nitrous oxide (N2O), which are attributed to vitamin B12 deficiency, have been well documented. With…”
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SULF2 strongly prediposes to fasting and postprandial triglycerides in patients with obesity and type 2 diabetes mellitus
Published in Obesity (Silver Spring, Md.) (01-05-2014)“…Objective Hepatic overexpression of sulfatase‐2 (SULF2), a heparan sulfate remodeling enzyme, strongly contributes to high triglyceride (TG) levels in obese,…”
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Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans[S]
Published in Journal of lipid research (01-03-2015)“…Elevated nonfasting TG-rich lipoprotein levels are a risk factor for CVD. To further evaluate the relevance of LDL-receptor (LDLr) pathway and heparan sulfate…”
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