Search Results - "Moody, Olivia A"

De novo variants in GABRA2 and GABRA5 alter receptor function and contribute to early-onset epilepsy by Butler, Kameryn M, Moody, Olivia A, Schuler, Elisabeth, Coryell, Jason, Alexander, John J, Jenkins, Andrew, Escayg, Andrew

“…GABAA receptors are important regulators of neuronal inhibition. Butler et al. identify de novo variants in GABRA2 and GABRA5, encoding α2 and α5 receptor…”
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Return of the Righting Reflex Does Not Portend Recovery of Cognitive Function in Anesthetized Rats by Vincent, Kathleen F, Zhang, Edlyn R, Kato, Risako, Cho, Angel, Moody, Olivia A, Solt, Ken

“…As the number of individuals undergoing general anesthesia rises globally, it becomes increasingly important to understand how consciousness and cognition are…”
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D-Amphetamine Accelerates Recovery of Consciousness and Respiratory Drive After High-Dose Fentanyl in Rats by Moody, Olivia A, Zhang, Edlyn R, Arora, Vipin, Kato, Risako, Cotten, Joseph F, Solt, Ken

“…In the United States, fentanyl causes approximately 60,000 drug overdose deaths each year. Fentanyl is also frequently administered as an analgesic in the…”
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Electrical stimulation of the ventral tegmental area restores consciousness from sevoflurane-, dexmedetomidine-, and fentanyl-induced unconsciousness in rats by Vincent, Kathleen F., Zhang, Edlyn R., Cho, Angel J., Kato-Miyabe, Risako, Mallari, Olivia G., Moody, Olivia A., Obert, David P., Park, Gwi H., Solt, Ken

“…Dopaminergic neurons in the ventral tegmental area (VTA) are crucially involved in regulating arousal, making them a potential target for reversing general…”
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D-Amphetamine Rapidly Reverses Dexmedetomidine-Induced Unconsciousness in Rats by Kato, Risako, Zhang, Edlyn R., Mallari, Olivia G., Moody, Olivia A., Vincent, Kathleen F., Melonakos, Eric D., Siegmann, Morgan J., Nehs, Christa J., Houle, Timothy T., Akeju, Oluwaseun, Solt, Ken

“…D-amphetamine induces emergence from sevoflurane and propofol anesthesia in rats. Dexmedetomidine is an α 2 -adrenoreceptor agonist that is commonly used for…”
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Ionotropic GABA and Glutamate Receptor Mutations and Human Neurologic Diseases by Yuan, Hongjie, Low, Chian-Ming, Moody, Olivia A, Jenkins, Andrew, Traynelis, Stephen F

“…The advent of whole exome/genome sequencing and the technology-driven reduction in the cost of next-generation sequencing as well as the introduction of…”
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The Neural Circuits Underlying General Anesthesia and Sleep by Moody, Olivia A., Zhang, Edlyn R., Vincent, Kathleen F., Kato, Risako, Melonakos, Eric D., Nehs, Christa J., Solt, Ken

“…General anesthesia is characterized by loss of consciousness, amnesia, analgesia, and immobility. Important molecular targets of general anesthetics have been…”
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Manipulating Neural Circuits in Anesthesia Research by Melonakos, Eric D., Moody, Olivia A., Nikolaeva, Ksenia, Kato, Risako, Nehs, Christa J., Solt, Ken

“…The neural circuits underlying the distinct endpoints that define general anesthesia remain incompletely understood. It is becoming increasingly evident,…”
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Modulating native GABA A receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death by Kallay, Laura, Keskin, Havva, Ross, Alexandra, Rupji, Manali, Moody, Olivia A, Wang, Xin, Li, Guanguan, Ahmed, Taukir, Rashid, Farjana, Stephen, Michael Rajesh, Cottrill, Kirsten A, Nuckols, T Austin, Xu, Maxwell, Martinson, Deborah E, Tranghese, Frank, Pei, Yanxin, Cook, James M, Kowalski, Jeanne, Taylor, Michael D, Jenkins, Andrew, Pomeranz Krummel, Daniel A, Sengupta, Soma

“…Pediatric brain cancer medulloblastoma (MB) standard-of-care results in numerous comorbidities. MB is comprised of distinct molecular subgroups. Group 3…”
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The role of loops B and C in determining the potentiation of GABA A receptors by midazolam by Moody, Olivia A, Jenkins, Andrew

“…Many benzodiazepines are positive allosteric modulators (PAMs) of GABA receptors that cause sedation, hypnosis, and anxiolysis. Benzodiazepines bind GABA…”
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The role of loops B and C in determining the potentiation of GABAA receptors by midazolam by Moody, Olivia A., Jenkins, Andrew

“…Many benzodiazepines are positive allosteric modulators (PAMs) of GABAA receptors that cause sedation, hypnosis, and anxiolysis. Benzodiazepines bind GABAA…”
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Rigor, reproducibility, and in vitro cerebrospinal fluid assays: The devil in the details by Moody, Olivia A., Talwar, Sahil, Jenkins, Meagan A., Freeman, Amanda A., Trotti, Lynn Marie, García, Paul S., Bliwise, Donald, Lynch, Joseph W., Cherson, Brad, Hernandez, Eric M., Feldman, Neil, Saini, Prabhjyot, Rye, David B., Jenkins, Andrew

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Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death by Kallay, Laura, Keskin, Havva, Ross, Alexandra, Rupji, Manali, Moody, Olivia A., Wang, Xin, Li, Guanguan, Ahmed, Taukir, Rashid, Farjana, Stephen, Michael Rajesh, Cottrill, Kirsten A., Nuckols, T. Austin, Xu, Maxwell, Martinson, Deborah E., Tranghese, Frank, Pei, Yanxin, Cook, James M., Kowalski, Jeanne, Taylor, Michael D., Jenkins, Andrew, Pomeranz Krummel, Daniel A., Sengupta, Soma

“…Purpose Pediatric brain cancer medulloblastoma (MB) standard-of-care results in numerous comorbidities. MB is comprised of distinct molecular subgroups. Group…”
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Cleaning Patch Clamp Pipettes Enables their Reuse by Kolb, Ilya, Stoy, William A., Rousseau, Erin, Moody, Olivia A., Jenkins, Andrew, Forest, Craig R.

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Abstract 2623: Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death by Kallay, Laura, Keskin, Havva, Ross, Alexandra, Rupji, Manali, Moody, Olivia A., Wang, Xin, Li, Guanguan, Ahmed, Taukir, Rashid, Farjana, Stephen, Michael Rajesh, Cottrill, Kirsten A., Nuckois, Austin, Xu, Maxwell, Martinson, Deborah E., Tranghese, Frank, Pei, Yanxin, Cook, James M., Kowalski, Jeanne, Taylor, Michael D., Jenkins, Andrew, Krummel, Daniel Pomeranz, Sengupta, Soma

“…Abstract Pediatric brain cancer medulloblastoma standard-of-care results in numerous comorbidities. Medulloblastoma is comprised of four molecular subgroups…”
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Rigor, Reproducibility and in vitro CSF assays: The Devil in the Details by Moody, Olivia A., Talwar, Sahil, Jenkins, Meagan A., Freeman, Amanda A., Trotti, Lynn Marie, García, Paul S., Bliwise, Donald, Lynch, Joseph W., Cherson, Brad, Hernandez, Eric M, Feldman, Neil, Saini, Prabhjyot, Rye, David B., Jenkins, Andrew

“…Divergent results and misinterpretation of non-significant findings remain problematic in science – especially in retrospective, hypothesis generating,…”
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