Search Results - "Moody, Harold M"
-
1
Fully Enzymatic Peptide Synthesis using C-Terminal tert-Butyl Ester Interconversion
Published in Advanced synthesis & catalysis (04-10-2010)“…Chemoenzymatic peptide synthesis is potentially the most cost‐efficient technology for the synthesis of short and medium‐sized peptides with some important…”
Get full text
Journal Article -
2
Penicillin acylase-catalyzed synthesis of β-lactam antibiotics in highly condensed aqueous systems: Beneficial impact of kinetic substrate supersaturation
Published in Biotechnology and bioengineering (05-02-2004)“…Advantages of performing penicillin acylase‐catalyzed synthesis of new penicillins and cephalosporins by enzymatic acyl transfer to the β‐lactam antibiotic…”
Get full text
Journal Article -
3
Asymmetric Strecker Synthesis of α-Amino Acids via a Crystallization-Induced Asymmetric Transformation Using (R)-Phenylglycine Amide as Chiral Auxiliary
Published in Organic letters (19-04-2001)“…Diastereoselective Strecker reactions based on (R)-phenylglycine amide as chiral auxiliary are reported. The Strecker reaction is accompanied by an in situ…”
Get full text
Journal Article -
4
Penicillin acylase-catalyzed synthesis of ampicillin in “aqueous solution–precipitate” systems. High substrate concentration and supersaturation effect
Published in Journal of molecular catalysis. B, Enzymatic (02-10-2000)“…Penicillin acylase-catalyzed ampicillin synthesis via acyl group transfer in aqueous solution is highly dependent on the initial substrate concentration. The…”
Get full text
Journal Article -
5
Synthesis of phosphate-methylated DNA fragments using 9-fluorenylmethoxycarbonyl as transient base protecting group
Published in Journal of organic chemistry (01-03-1989)Get full text
Journal Article -
6
Resolution of ( RS)-phenylglycinonitrile by penicillin acylase-catalyzed acylation in aqueous medium
Published in Tetrahedron: asymmetry (05-09-2003)“…A new strategy for the biocatalytic resolution of ( R, S)-phenylglycinonitrile, a crucial intermediate in the antibiotic industry, has been developed. While…”
Get full text
Journal Article -
7
Regiospecific inhibition of DNA duplication by antisense phosphate-methylated oligodeoxynucleotides
Published in Nucleic acids research (26-06-1989)“…A new synthesis route for long phosphate-methylated oligodeoxynucleotides is described, which were used as antisense inhibitors of the DNA replication…”
Get full text
Journal Article -
8