Search Results - "Moody, D"

The "Physics" of Notations: Toward a Scientific Basis for Constructing Visual Notations in Software Engineering by Moody, D.

“…Visual notations form an integral part of the language of software engineering (SE). Yet historically, SE researchers and notation designers have ignored or…”
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Efficient and precise single-cell reference atlas mapping with Symphony by Kang, Joyce B., Nathan, Aparna, Weinand, Kathryn, Zhang, Fan, Millard, Nghia, Rumker, Laurie, Moody, D. Branch, Korsunsky, Ilya, Raychaudhuri, Soumya

“…Recent advances in single-cell technologies and integration algorithms make it possible to construct comprehensive reference atlases encompassing many donors,…”
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The burgeoning family of unconventional T cells by Godfrey, Dale I, Uldrich, Adam P, McCluskey, James, Rossjohn, Jamie, Moody, D Branch

“…While most studies of T lymphocytes have focused on peptide-MHC-reactive T cells, many other types of T cells do not fit this paradigm. Here Godfrey et al …”
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CD1 and mycobacterial lipids activate human T cells by Van Rhijn, Ildiko, Moody, D. Branch

“…Summary For decades, proteins were thought to be the sole or at least the dominant source of antigens for T cells. Studies in the 1990s demonstrated that CD1…”
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Remembering Enzo Cerundolo by Moody, D. Branch

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Lipid and small-molecule display by CD1 and MR1 by Van Rhijn, Ildiko, Godfrey, Dale I., Rossjohn, Jamie, Moody, D. Branch

“…Key Points Whereas peptide–MHC complexes are the usual model for technology development focused on T cells, the discovery of lipids and non-lipid small…”
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Multivariate resting-state functional connectivity predicts response to cognitive behavioral therapy in obsessive–compulsive disorder by Reggente, Nicco, Moody, Teena D., Morfini, Francesca, Sheen, Courtney, Rissman, Jesse, O’Neill, Joseph, Feusner, Jamie D.

“…Cognitive behavioral therapy (CBT) is an effective treatment for many with obsessive–compulsive disorder (OCD). However, response varies considerably among…”
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CD1 displays its own negative regulators by Shahine, Adam, Van Rhijn, Ildiko, Rossjohn, Jamie, Moody, D. Branch

“…After two decades of the study of lipid antigens that activate CD1-restricted T cells, new studies show how autoreactive αβ T-cell receptors (TCRs) can…”
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How T cells grasp mycobacterial lipid antigens by Moody, D. Branch

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Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease by Nathan, Aparna, Beynor, Jessica I., Baglaenko, Yuriy, Suliman, Sara, Ishigaki, Kazuyoshi, Asgari, Samira, Huang, Chuan-Chin, Luo, Yang, Zhang, Zibiao, Lopez, Kattya, Lindestam Arlehamn, Cecilia S., Ernst, Joel D., Jimenez, Judith, Calderón, Roger I., Lecca, Leonid, Van Rhijn, Ildiko, Moody, D. Branch, Murray, Megan B., Raychaudhuri, Soumya

“…Multimodal T cell profiling can enable more precise characterization of elusive cell states underlying disease. Here, we integrated single-cell RNA and surface…”
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αβ T-cell receptor recognition of self-phosphatidylinositol presented by CD1b by Farquhar, Rachel, Van Rhijn, Ildiko, Moody, D. Branch, Rossjohn, Jamie, Shahine, Adam

“…CD1 glycoproteins present lipid-based antigens to T-cell receptors (TCRs). A role for CD1b in T-cell–mediated autoreactivity was proposed when it was…”
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Protein kinases PknA and PknB independently and coordinately regulate essential Mycobacterium tuberculosis physiologies and antimicrobial susceptibility by Zeng, Jumei, Platig, John, Cheng, Tan-Yun, Ahmed, Saima, Skaf, Yara, Potluri, Lakshmi-Prasad, Schwartz, Daniel, Steen, Hanno, Moody, D Branch, Husson, Robert N

“…The Mycobacterium tuberculosis Ser/Thr protein kinases PknA and PknB are essential for growth and have been proposed as possible drug targets. We used a…”
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Donor Unrestricted T Cells: A Shared Human T Cell Response by Van Rhijn, Ildiko, Moody, D Branch

“…The now-famous term "restriction" derived from experiments in which T cells from Donor A failed to recognize Ags presented by cells from Donor B. Restriction…”
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CD1a and bound lipids drive T‐cell responses in human skin disease by Ogg, Graham S., Rossjohn, Jamie, Clark, Rachael A., Moody, D. Branch

“…In addition to serving as the main physical barrier with the outside world, human skin is abundantly infiltrated with resident αβ T cells that respond…”
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Origins and Scaling of Hot-Electron Preheat in Ignition-Scale Direct-Drive Inertial Confinement Fusion Experiments by Rosenberg, M J, Solodov, A A, Myatt, J F, Seka, W, Michel, P, Hohenberger, M, Short, R W, Epstein, R, Regan, S P, Campbell, E M, Chapman, T, Goyon, C, Ralph, J E, Barrios, M A, Moody, J D, Bates, J W

“…Planar laser-plasma interaction (LPI) experiments at the National Ignition Facility (NIF) have allowed access for the first time to regimes of electron density…”
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The Mycobacterium tuberculosis regulatory network and hypoxia by Galagan, James E., Minch, Kyle, Peterson, Matthew, Lyubetskaya, Anna, Azizi, Elham, Sweet, Linsday, Gomes, Antonio, Rustad, Tige, Dolganov, Gregory, Glotova, Irina, Abeel, Thomas, Mahwinney, Chris, Kennedy, Adam D., Allard, René, Brabant, William, Krueger, Andrew, Jaini, Suma, Honda, Brent, Yu, Wen-Han, Hickey, Mark J., Zucker, Jeremy, Garay, Christopher, Weiner, Brian, Sisk, Peter, Stolte, Christian, Winkler, Jessica K., Van de Peer, Yves, Iazzetti, Paul, Camacho, Diogo, Dreyfuss, Jonathan, Liu, Yang, Dorhoi, Anca, Mollenkopf, Hans-Joachim, Drogaris, Paul, Lamontagne, Julie, Zhou, Yiyong, Piquenot, Julie, Park, Sang Tae, Raman, Sahadevan, Kaufmann, Stefan H. E., Mohney, Robert P., Chelsky, Daniel, Moody, D. Branch, Sherman, David R., Schoolnik, Gary K.

“…We have taken the first steps towards a complete reconstruction of the Mycobacterium tuberculosis regulatory network based on ChIP-Seq and combined this…”
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Dynamic control of the polarization of intense laser beams via optical wave mixing in plasmas by Michel, P, Divol, L, Turnbull, D, Moody, J D

“…When intense laser beams overlap in plasmas, the refractive index modulation created by the beat wave via the ponderomotive force can lead to optical wave…”
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Brain health consequences of digital technology use by Small, Gary W., Lee, Jooyeon, Kaufman, Aaron, Jalil, Jason, Siddarth, Prabha, Gaddipati, Himaja, Moody, Teena D., Bookheimer, Susan Y.

“…Emerging scientific evidence indicates that frequent digital technology use has a significant impact-both negative and positive-on brain function and behavior…”
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Four pathways of CD1 antigen presentation to T cells by Moody, D Branch, Cotton, Rachel N

“…•Human CD1a, CD1b, CD1c, and CD1d use distinct pathways for trafficking and antigen capture.•CD1a, CD1b and CD1c have inducible expression, yet upstream…”
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Interpreting expression data with metabolic flux models: predicting Mycobacterium tuberculosis mycolic acid production by Colijn, Caroline, Brandes, Aaron, Zucker, Jeremy, Lun, Desmond S, Weiner, Brian, Farhat, Maha R, Cheng, Tan-Yun, Moody, D Branch, Murray, Megan, Galagan, James E

“…Metabolism is central to cell physiology, and metabolic disturbances play a role in numerous disease states. Despite its importance, the ability to study…”
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