Search Results - "Moody, Christopher J."

Quinones as Dienophiles in the Diels-Alder Reaction: History and Applications in Total Synthesis by Nawrat, Christopher C., Moody, Christopher J.

“…In the canon of reactions available to the organic chemist engaged in total synthesis, the Diels–Alder reaction is among the most powerful and well understood…”
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Mega-evolutionary dynamics of the adaptive radiation of birds by Cooney, Christopher R., Bright, Jen A., Capp, Elliot J. R., Chira, Angela M., Hughes, Emma C., Moody, Christopher J. A., Nouri, Lara O., Varley, Zoë K., Thomas, Gavin H.

“…A study of more than 2,000 bird species shows that diversity in bill shape expands towards extreme morphologies early in avian evolution in a series of major…”
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Sexual selection predicts the rate and direction of colour divergence in a large avian radiation by Cooney, Christopher R., Varley, Zoë K., Nouri, Lara O., Moody, Christopher J. A., Jardine, Michael D., Thomas, Gavin H.

“…Sexual selection is proposed to be a powerful driver of phenotypic evolution in animal systems. At macroevolutionary scales, sexual selection can theoretically…”
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From Amino Acids to Heteroaromatics--Thiopeptide Antibiotics, Nature's Heterocyclic Peptides by Hughes, Rachael A, Moody, Christopher J

“…Amino acids, the building blocks of proteins, also serve as precursors to a wide range of other naturally occurring substances including alkaloids,…”
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Solar Photochemical Oxidation of Alcohols using Catalytic Hydroquinone and Copper Nanoparticles under Oxygen: Oxidative Cleavage of Lignin Models by Mitchell, Lorna J, Moody, Christopher J

“…Alcohols are converted into to their corresponding carbonyl compounds using catalytic amounts of 1,4-hydroquinone with a copper nanoparticle electron transfer…”
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Stereoselective Synthesis of Highly Substituted Tetrahydrofurans through Diverted Carbene OH Insertion Reaction by Nicolle, Simon M., Lewis, William, Hayes, Christopher J., Moody, Christopher J.

“…Copper‐ or rhodium‐catalyzed reactions of diazocarbonyl compounds with β‐hydroxyketones give highly substituted tetrahydrofurans with excellent…”
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Enantioselective Insertion of Metal Carbenes into N----H Bonds: A Potentially Versatile Route to Chiral Amine Derivatives by Moody, Christopher J

“…Back to copper: The Rh‐catalyzed reactions of diazocarbonyl compounds with amines, leading to NH insertion products, have found wide application. However, an…”
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Deep learning image segmentation reveals patterns of UV reflectance evolution in passerine birds by He, Yichen, Varley, Zoë K., Nouri, Lara O., Moody, Christopher J. A., Jardine, Michael D., Maddock, Steve, Thomas, Gavin H., Cooney, Christopher R.

“…Ultraviolet colouration is thought to be an important form of signalling in many bird species, yet broad insights regarding the prevalence of ultraviolet…”
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Heat shock protein 90 controls HIV-1 reactivation from latency by Anderson, Ian, Low, Jun Siong, Weston, Stuart, Weinberger, Michael, Zhyvoloup, Alexander, Labokha, Aksana A, Corazza, Gianmarco, Kitson, Russell A, Moody, Christopher J, Marcello, Alessandro, Fassati, Ariberto

“…Latency allows HIV-1 to persist in long-lived cellular reservoirs, preventing virus eradication. We have previously shown that the heat shock protein 90…”
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Alkyl Halide-Free Heteroatom Alkylation and Epoxidation Facilitated by a Recyclable Polymer-Supported Oxidant for the In-Flow Preparation of Diazo Compounds by Nicolle, Simon M., Hayes, Christopher J., Moody, Christopher J.

“…Highly reactive metal carbenes, generated from simple ketones via diazo compounds, including diazo‐amides and ‐phosphonates, using a recyclable reagent…”
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The synthetic challenge of diazonamide A, a macrocyclic indole bis-oxazole marine natural product by Lachia, Mathilde, Moody, Christopher J

“…The complex structure of the marine metabolic diazonamide A comprises a dichlorinated indole bis-oxazole heteroaromatic fragment, and a [b]-fused…”
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Formal Total Synthesis of Diazonamide A by Indole Oxidative Rearrangement by David, Nadège, Pasceri, Raffaele, Kitson, Russell R. A., Pradal, Alexandre, Moody, Christopher J.

“…A short formal total synthesis of the marine natural product diazonamide A is described. The route is based on indole oxidative rearrangement, and a number of…”
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Total Synthesis of the Cyclic Dodecapeptides Wewakazole and Wewakazole B by Inman, Martyn, Dexter, Hannah L, Moody, Christopher J

“…The cyclic dodecapeptides wewakazole and wewakazole B have been synthesized by a divergent strategy via a common tris-proline containing oxazole octapeptide…”
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A two step route to indoles from haloarenes--a versatile variation on the Fischer indole synthesis by Inman, Martyn, Moody, Christopher J

“…In a new variation on the Fischer indole synthesis, readily available haloarenes are converted into a wide range of indoles in just two steps by…”
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Nitrogen‐Bridged, Natural Product Like Octahydrobenzofurans and Octahydroindoles: Scope and Mechanism of Bridge‐Forming Reductive Amination via Caged Heteroadamantanes by Wales, Steven. M., Adcock, Holly V., Lewis, William, Hamza, Daniel, Moody, Christopher J.

“…The biological significance of sp3‐rich synthetic scaffolds with natural product like features yet distinct global frameworks is being increasingly recognized…”
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Diverse Trifluoromethyl Heterocycles from a Single Precursor by Honey, Mark A, Pasceri, Raffaele, Lewis, William, Moody, Christopher J

“…Ethyl 2-diazo-4,4,4-trifluoro-3-oxobutanoate is a highly versatile intermediate for the synthesis of a wide range of trifluoromethyl heterocycles. With the use…”
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Rhodium Carbene Routes to Oxazoles and Thiazoles. Catalyst Effects in the Synthesis of Oxazole and Thiazole Carboxylates, Phosphonates, and Sulfones by Shi, Baolu, Blake, Alexander J, Lewis, William, Campbell, Ian B, Judkins, Brian D, Moody, Christopher J

“…Dirhodium tetraacetate catalyzed reaction of α-diazo-β-keto-carboxylates and -phosphonates with arenecarboxamides gives 2-aryloxazole-4-carboxylates and…”
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Latitudinal gradients in avian colourfulness by Cooney, Christopher R., He, Yichen, Varley, Zoë K., Nouri, Lara O., Moody, Christopher J. A., Jardine, Michael D., Liker, András, Székely, Tamás, Thomas, Gavin H.

“…It has long been suggested that tropical species are generally more colourful than temperate species, but whether latitudinal gradients in organismal…”
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Copper(II)-Mediated Synthesis of Indolequinones from Bromoquinones and Enamines by Inman, Martyn, Moody, Christopher J.

“…The reaction of enamines and bromoquinones in the presence of copper(II) acetate and potassium carbonate results in a regiospecific synthesis of…”
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In Vitro Anticancer Properties of Novel Bis-Triazoles by Saleh, Maysaa M, Abuarqoub, Duaa A, Hammad, Alaa M, Hossan, Md Shahadat, Ahmed, Najneen, Aslam, Nazneen, Naser, Abdallah Y, Moody, Christopher J, Laughton, Charles A, Bradshaw, Tracey D

“…Here, we describe the anticancer activity of our novel bis-triazoles MS47 and MS49, developed previously as G-quadruplex stabilizers, focusing specifically…”
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