Search Results - "Moochhala, Shabbir M."

The Gut-Skin Microbiota Axis and Its Role in Diabetic Wound Healing-A Review Based on Current Literature by Patel, Bharati Kadamb, Patel, Kadamb Haribhai, Huang, Ryan Yuki, Lee, Chuen Neng, Moochhala, Shabbir M

“…Diabetic foot ulcers (DFU) are a growing concern worldwide as they pose complications in routine clinical practices such as diagnosis and management. Bacterial…”
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Ultrashort peptide nanofibrous hydrogels for the acceleration of healing of burn wounds by Loo, Yihua, Wong, Yong-Chiat, Cai, Elijah Z, Ang, Chuan-Han, Raju, Ashvin, Lakshmanan, Anupama, Koh, Alvin G, Zhou, Hui J, Lim, Thiam-Chye, Moochhala, Shabbir M, Hauser, Charlotte A.E

“…Abstract There is an unmet clinical need for wound dressings to treat partial thickness burns that damage the epidermis and dermis. An ideal dressing needs to…”
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Endogenous Hydrogen Sulfide Regulates Inflammatory Response by Activating the ERK Pathway in Polymicrobial Sepsis by Zhang, Huili, Moochhala, Shabbir M, Bhatia, Madhav

“…Hydrogen sulfide (H(2)S) up-regulates inflammatory response in several inflammatory diseases. However, to date, little is known about the molecular mechanism…”
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Hydrogen sulfide and neurogenic inflammation in polymicrobial sepsis: involvement of substance P and ERK-NF-κB signaling by Ang, Seah-Fang, Moochhala, Shabbir M, MacAry, Paul A, Bhatia, Madhav

“…Hydrogen sulfide (H(2)S) has been shown to induce transient receptor potential vanilloid 1 (TRPV1)-mediated neurogenic inflammation in polymicrobial sepsis…”
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Endogenous hydrogen sulfide regulates leukocyte trafficking in cecal ligation and puncture-induced sepsis by Zhang, Huili, Zhi, Liang, Moochhala, Shabbir M., Moore, Philip Keith, Bhatia, Madhav

“…Hydrogen sulfide (H2S) is recognized increasingly as a proinflammatory mediator in various inflammatory conditions. Here, we have investigated the role of H2S…”
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Gut microbiota intervention strategies using active components from medicinal herbs to evaluate clinical efficacy of type 2 diabetes – A review by Patel, Bharati Kadamb, Patel, Kadamb Haribhai, Moochhala, Shabbir M.

“…There is a myriad of phytocomponents in various medicinal herbs, and some of these substances have low absolute oral bioavailability. There is a complex and…”
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Hydrogen sulfide upregulates cyclooxygenase-2 and prostaglandin E metabolite in sepsis-evoked acute lung injury via transient receptor potential vanilloid type 1 channel activation by Ang, Seah-Fang, Sio, Selena W S, Moochhala, Shabbir M, MacAry, Paul A, Bhatia, Madhav

“…Hydrogen sulfide (H(2)S) has been shown to promote transient receptor potential vanilloid type 1 (TRPV1)-mediated neurogenic inflammation in sepsis and its…”
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The function of microglia, either neuroprotection or neurotoxicity, is determined by the equilibrium among factors released from activated microglia in vitro by Li, Lv, Lu, Jia, Tay, Samuel Sam Wah, Moochhala, Shabbir M, He, Bei Ping

“…Abstract Opposing functions of activated microglia, namely neuroprotection or neurotrophy versus neurodestruction or neurotoxicity, have been observed in a…”
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Creation of Consistent Burn Wounds: A Rat Model by Cai, Elijah Zhengyang, Ang, Chuan Han, Raju, Ashvin, Tan, Kong Bing, Hing, Eileen Chor Hoong, Loo, Yihua, Wong, Yong Chiat, Lee, Hanjing, Lim, Jane, Moochhala, Shabbir M, Hauser, Charlotte AE, Lim, Thiam Chye

“…Background Burn infliction techniques are poorly described in rat models. An accurate study can only be achieved with wounds that are uniform in size and…”
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The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88 by Melendez, Alirio J, Puneet, Padmam, McGrath, Mairi A, Tay, Hwee Kee, Al-Riyami, Lamyaa, Rzepecka, Justyna, Moochhala, Shabbir M, Pervaiz, Shazib, Harnett, Margaret M, Harnett, William

“…Parasites use multifarious means to manipulate and avoid sterilizing immunity. Melendez and colleagues show that a nematode product triggers macrophage…”
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Hydrogen Sulfide Up-Regulates Substance P in Polymicrobial Sepsis-Associated Lung Injury by Zhang, Huili, Hegde, Akhil, Ng, Siaw Wei, Adhikari, Sharmila, Moochhala, Shabbir M, Bhatia, Madhav

“…Hydrogen sulfide (H2S) has been shown to induce the activation of neurogenic inflammation especially in normal airways and urinary bladder. However, whether…”
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Forebrain medial septum region facilitates nociception in a rat formalin model of inflammatory pain by Lee, Andy Thiam-Huat, Ariffin, Mohammed Zacky, Zhou, Mingyi, Ye, Jenn Zhou, Moochhala, Shabbir M., Khanna, Sanjay

“…The findings suggest that the medial septum is pro-nociceptive and facilitates central processing of nociceptive information. The region may coordinate…”
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Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis by Hegde, Akhil, Zhang, Huili, Moochhala, Shabbir M., Bhatia, Madhav

“…Earlier work from our laboratory has suggested a role for the neuropeptide substance P (SP) in inducing lung injury in sepsis. In that study, mice lacking the…”
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Metabolic Profiling of a Porcine Combat Trauma-Injury Model Using NMR and Multi-Mode LC-MS Metabolomics—A Preliminary Study by Laserna, Anna Karen Carrasco, Lai, Yiyang, Fang, Guihua, Ganapathy, Rajaseger, Atan, Mohamed Shirhan Bin Mohamed, Lu, Jia, Wu, Jian, Uttamchandani, Mahesh, Moochhala, Shabbir M., Li, Sam Fong Yau

“…Profiles of combat injuries worldwide have shown that penetrating trauma is one of the most common injuries sustained during battle. This is usually…”
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Low level primary blast injury in rodent brain by Pun, Pamela B L, Kan, Enci Mary, Salim, Agus, Li, Zhaohui, Ng, Kian Chye, Moochhala, Shabbir M, Ling, Eng-Ang, Tan, Mui Hong, Lu, Jia

“…The incidence of blast attacks and resulting traumatic brain injuries has been on the rise in recent years. Primary blast is one of the mechanisms in which the…”
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Role of hydrogen sulfide in acute pancreatitis and associated lung injury by Bhatia, Madhav, Wong, Fei Ling, Fu, Di, Lau, Hon Yen, Moochhala, Shabbir M, Moore, Philip K

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Preprotachykinin-A Gene Products Are Key Mediators of Lung Injury in Polymicrobial Sepsis by Puneet, Padmam, Hegde, Akhil, Ng, Siaw Wei, Lau, Hon Yen, Lu, Jia, Moochhala, Shabbir M, Bhatia, Madhav

“…Preprotachykinin-A (PPT-A) gene products substance P and neurokinin-A have been shown to play an important role in neurogenic inflammation. To investigate the…”
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Electrochemical Detection of Nitric Oxide on a SWCNT/RTIL Composite Gel Microelectrode by Li, Chang Ming, Zang, Jianfeng, Zhan, Dongping, Chen, Wei, Sun, Chang Q., Teo, Ai. L., Chua, Yek. T., Lee, Vee. S., Moochhala, Shabbir. M.

“…Single walled carbon nanotubes (SWCNT) and room temperature ionic liquid (RTIL) were used to make a gel microelectrode for studies of the oxidation of nitric…”
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Gut microbiome in acute pancreatitis: A review based on current literature by Patel, Bharati Kadamb, Patel, Kadamb H, Bhatia, Madhav, Iyer, Shridhar Ganpati, Madhavan, Krishnakumar, Moochhala, Shabbir M

“…The gut microbiome is a complex microbial community, recognized for its potential role in physiology, health, and disease. The available evidence supports the…”
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Development of a chitosan-based wound dressing with improved hemostatic and antimicrobial properties by Ong, Shin-Yeu, Wu, Jian, Moochhala, Shabbir M, Tan, Mui-Hong, Lu, Jia

“…Abstract Hemorrhage remains a leading cause of early death after trauma, and infectious complications in combat wounds continue to challenge caregivers…”
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