Search Results - "Monzon, Alexander Miguel"

Conformational diversity and the emergence of sequence signatures during evolution by Parisi, Gustavo, Zea, Diego Javier, Monzon, Alexander Miguel, Marino-Buslje, Cristina

“…•Protein's native structure is an ensemble of conformers with similar energies.•Conformational diversity constraints sequence divergence.•High conformational…”
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On the dynamical incompleteness of the Protein Data Bank by Marino-Buslje, Cristina, Monzon, Alexander Miguel, Zea, Diego Javier, Fornasari, María Silvina, Parisi, Gustavo

“…Abstract Major scientific challenges that are beyond the capability of individuals need to be addressed by multi-disciplinary and multi-institutional…”
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Conformational diversity analysis reveals three functional mechanisms in proteins by Monzon, Alexander Miguel, Zea, Diego Javier, Fornasari, María Silvina, Saldaño, Tadeo E, Fernandez-Alberti, Sebastian, Tosatto, Silvio C E, Parisi, Gustavo

“…Protein motions are a key feature to understand biological function. Recently, a large-scale analysis of protein conformational diversity showed a positively…”
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CoDNaS 2.0: a comprehensive database of protein conformational diversity in the native state by Monzon, Alexander Miguel, Rohr, Cristian Oscar, Fornasari, María Silvina, Parisi, Gustavo

“…CoDNaS (conformational diversity of the native state) is a protein conformational diversity database. Conformational diversity describes structural differences…”
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Reflections on a journey: a retrospective of the ISCB Student Council symposium series by Hassan, Mehedi, Namasivayam, Aishwarya Alex, DeBlasio, Dan, Fatima, Nazeefa, Siranosian, Benjamin, Parra, R Gonzalo, Cuypers, Bart, Shome, Sayane, Monzon, Alexander Miguel, Fumey, Julien, Rahman, Farzana

“…This article describes the motivation, origin and evolution of the student symposia series organised by the ISCB Student Council. The meeting series started…”
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Disorder transitions and conformational diversity cooperatively modulate biological function in proteins by Zea, Diego Javier, Monzon, Alexander Miguel, Gonzalez, Claudia, Fornasari, María Silvina, Tosatto, Silvio C. E., Parisi, Gustavo

“…Structural differences between conformers sustain protein biological function. Here, we studied in a large dataset of 745 intrinsically disordered proteins,…”
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Addressing the Role of Conformational Diversity in Protein Structure Prediction by Palopoli, Nicolas, Monzon, Alexander Miguel, Parisi, Gustavo, Fornasari, Maria Silvina

“…Computational modeling of tertiary structures has become of standard use to study proteins that lack experimental characterization. Unfortunately, 3D structure…”
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CoDNaS: a database of conformational diversity in the native state of proteins by Monzon, Alexander Miguel, Juritz, Ezequiel, Fornasari, María Silvina, Parisi, Gustavo

“…Conformational diversity is a key concept in the understanding of different issues related with protein function such as the study of catalytic processes in…”
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Large scale analysis of protein conformational transitions from aqueous to non-aqueous media by Rueda, Ana Julia Velez, Monzon, Alexander Miguel, Ardanaz, Sebastián M, Iglesias, Luis E, Parisi, Gustavo

“…Biocatalysis in organic solvents is nowadays a common practice with a large potential in Biotechnology. Several studies report that proteins which are…”
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Seasonal variation in genetic population structure of sábalo (Prochilodus lineatus) in the Lower Uruguay River by Rueda, Eva Carolina, Carriquiriborde, Pedro, Monzón, Alexander Miguel, Somoza, Gustavo M, Ortí, Guillermo

“…Prochilodus lineatus is a highly migratory fish species that sustains the most important commercial fishery of Paraná-Paraguay basin. Migratory patterns are…”
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Intrinsic protein disorder and conditional folding in AlphaFoldDB by Piovesan, Damiano, Monzon, Alexander Miguel, Tosatto, Silvio C. E.

“…Intrinsically disordered regions (IDRs) defying the traditional protein structure–function paradigm have been difficult to analyze. The availability of…”
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A Novel Splice Variant of Human TGF-β Type II Receptor Encodes a Soluble Protein and Its Fc-Tagged Version Prevents Liver Fibrosis in vivo by Bertolio, Marcela Soledad, La Colla, Anabela, Carrea, Alejandra, Romo, Ana, Canziani, Gabriela, Echarte, Stella Maris, Campisano, Sabrina, Barletta, German Patricio, Monzon, Alexander Miguel, Rodríguez, Tania Melina, Chisari, Andrea Nancy, Dewey, Ricardo Alfredo

“…We describe, for the first time, a new splice variant of the human TGF-β type II receptor (TβRII). The new transcript lacks 149 nucleotides, resulting in a…”
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RING 3.0: fast generation of probabilistic residue interaction networks from structural ensembles by Clementel, Damiano, Del Conte, Alessio, Monzon, Alexander Miguel, Camagni, Giorgia F, Minervini, Giovanni, Piovesan, Damiano, Tosatto, Silvio C E

“…Abstract Residue interaction networks (RINs) are used to represent residue contacts in protein structures. Thanks to the advances in network theory, RINs have…”
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MobiDB: 10 years of intrinsically disordered proteins by Piovesan, Damiano, Del Conte, Alessio, Clementel, Damiano, Monzon, Alexander Miguel, Bevilacqua, Martina, Aspromonte, Maria Cristina, Iserte, Javier A, Orti, Fernando E, Marino-Buslje, Cristina, Tosatto, Silvio C E

“…The MobiDB database (URL: https://mobidb.org/) is a knowledge base of intrinsically disordered proteins. MobiDB aggregates disorder annotations derived from…”
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Critical assessment of protein intrinsic disorder prediction (CAID) ‐ Results of round 2 by Conte, Alessio Del, Mehdiabadi, Mahta, Bouhraoua, Adel, Miguel Monzon, Alexander, Tosatto, Silvio C. E., Piovesan, Damiano

“…Protein intrinsic disorder (ID) is a complex and context‐dependent phenomenon that covers a continuum between fully disordered states and folded states with…”
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Diversity and structural‐functional insights of alpha‐solenoid proteins by Arrías, Paula Nazarena, Osmanli, Zarifa, Peralta, Estefanía, Chinestrad, Patricio Manuel, Monzon, Alexander Miguel, Tosatto, Silvio C. E.

“…Alpha‐solenoids are a significant and diverse subset of structured tandem repeat proteins (STRPs) that are important in various domains of life. This review…”
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Databases for intrinsically disordered proteins by Piovesan, Damiano, Monzon, Alexander Miguel, Quaglia, Federica, Tosatto, Silvio C. E.

“…Intrinsically disordered regions (IDRs) lacking a fixed three‐dimensional protein structure are widespread and play a central role in cell regulation. Only a…”
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Homology modeling in a dynamical world by Monzon, Alexander Miguel, Zea, Diego Javier, Marino‐Buslje, Cristina, Parisi, Gustavo

“…A key concept in template‐based modeling (TBM) is the high correlation between sequence and structural divergence, with the practical consequence that…”
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Experimentally Determined Long Intrinsically Disordered Protein Regions Are Now Abundant in the Protein Data Bank by Monzon, Alexander Miguel, Necci, Marco, Quaglia, Federica, Walsh, Ian, Zanotti, Giuseppe, Piovesan, Damiano, Tosatto, Silvio C E

“…Intrinsically disordered protein regions are commonly defined from missing electron density in X-ray structures. Experimental evidence for long disorder…”
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RepeatsDB in 2025: expanding annotations of structured tandem repeats proteins on AlphaFoldDB by Clementel, Damiano, Arrías, Paula Nazarena, Mozaffari, Soroush, Osmanli, Zarifa, Castro, Ximena Aixa, Ferrari, Carlo, Kajava, Andrey V, Tosatto, Silvio C E, Monzon, Alexander Miguel

“…RepeatsDB (URL: https://repeatsdb.org) stands as a key resource for the classification and annotation of Structured Tandem Repeat Proteins (STRPs),…”
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