Search Results - "Monti, Maria C."
-
1
Shared molecular amino acid signature in the HLA-DR peptide binding pocket predisposes to both autoimmune diabetes and thyroiditis
Published in Proceedings of the National Academy of Sciences - PNAS (28-09-2010)“…There is strong genetic association between type 1A diabetes (T1D) and autoimmune thyroid disease (AITD). T1D and AITD frequently occur together in the same…”
Get full text
Journal Article -
2
Effects of Hst3p inhibition in Candida albicans : a genome-wide H3K56 acetylation analysis
Published in Frontiers in cellular and infection microbiology (27-10-2022)“…spp. represent the third most frequent worldwide cause of infection in Intensive Care Units with a mortality rate of almost 40%. The classes of antifungals…”
Get full text
Journal Article -
3
Involvement of nNOS/NO/sGC/cGMP signaling pathway in cocaine sensitization and in the associated hippocampal alterations: does phosphodiesterase 5 inhibition help to drug vulnerability?
Published in Psychopharmacology (01-09-2013)“…Rationale Repeated cocaine administration induces behavioral sensitization in about 50 % of treated animals. Nitric oxide could be involved in the acquisition…”
Get full text
Journal Article -
4
Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases
Published in Frontiers in pharmacology (30-03-2017)“…Bile acid (BA) receptors represent well-defined targets for the development of novel therapeutic approaches to metabolic and inflammatory diseases. In the…”
Get full text
Journal Article -
5
Molecular Amino Acid Signatures in the MHC Class II Peptide-Binding Pocket Predispose to Autoimmune Thyroiditis in Humans and in Mice
Published in Proceedings of the National Academy of Sciences - PNAS (16-09-2008)“…Hashimoto's thyroiditis (HT) is associated with HLA, but the associated allele is still controversial. We hypothesized that specific HLA-DR pocket-sequence…”
Get full text
Journal Article -
6
Identification of Trombospondin-1 as a Novel Amelogenin Interactor by Functional Proteomics
Published in Frontiers in chemistry (09-10-2017)“…Amelogenins are a set of low molecular-weight enamel proteins belonging to a group of extracellular matrix (ECM) proteins with a key role in tooth enamel…”
Get full text
Journal Article -
7
Crellastatin A, a PARP‐1 Inhibitor Discovered by Complementary Proteomic Approaches
Published in ChemMedChem (05-02-2020)“…Crellastatin A, a cytotoxic sulfated bis‐steroid isolated from the Vanuatu Island marine sponge Crella sp., was selected as an interesting probe for a…”
Get full text
Journal Article -
8
Linkage Analysis of Genomic Regions Contributing to the Expression of Type 1 Diabetes Microvascular Complications and Interaction with HLA
Published in Journal of diabetes research (01-01-2015)“…We conducted linkage analysis to follow up earlier work on microvascular complications of type 1 diabetes (T1D). We analyzed 415 families (2,008 individuals)…”
Get full text
Journal Article -
9
Gout impacts on function and health-related quality of life beyond associated risk factors and medical conditions: results from the KING observational study of the Italian Society for Rheumatology (SIR)
Published in Arthritis research & therapy (03-09-2013)“…Gout is the most prevalent arthritis and significantly impacts on function and quality of life. Given that gout associates with disabling comorbid conditions,…”
Get full text
Journal Article -
10
Familial Risk Factors for Microvascular Complications and Differential Male-Female Risk in a Large Cohort of American Families with Type 1 Diabetes
Published in The journal of clinical endocrinology and metabolism (01-12-2007)“…Context: Type 1 diabetes (T1D) complications are responsible for much of the disease morbidity. Evidence suggests that familial factors exert an influence on…”
Get full text
Journal Article -
11
Impact of contextual cues in the expression of the memory associated with diazepam withdrawal: involvement of hippocampal PKMζin vivo, and Arc expression and LTP in vitro
Published in The European journal of neuroscience (01-10-2012)“…Hippocampal synaptic plasticity has been related to learning and adaptive processes developed during chronic drug administration, suggesting the existence of a…”
Get full text
Journal Article -
12
Interactions of Kid-Kis toxin-antitoxin complexes with the parD operator-promoter region of plasmid R1 are piloted by the Kis antitoxin and tuned by the stoichiometry of Kid-Kis oligomers
Published in Nucleic acids research (01-03-2007)“…The parD operon of Escherichia coli plasmid R1 encodes a toxin-antitoxin system, which is involved in plasmid stabilization. The toxin Kid inhibits cell growth…”
Get full text
Journal Article -
13
Mortality due to sudden infant death syndrome in Northern Italy, 1990-2000: a baseline for the assessment of prevention campaigns
Published in Paediatric and perinatal epidemiology (01-09-2004)“…Summary The aim of this paper is to estimate the infant mortality rate and the incidence of sudden infant death syndrome (SIDS) in Lombardy, Northern Italy, in…”
Get full text
Journal Article