Search Results - "Montgomery, Karienn S"
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Dopaminergic modulation of risky decision-making
Published in The Journal of neuroscience (30-11-2011)“…Many psychiatric disorders are characterized by abnormal risky decision-making and dysregulated dopamine receptor expression. The current study was designed to…”
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Amitriptyline Decreases GABAergic Transmission in Basal Forebrain Neurons Using an Optogenetic Model of Aging
Published in Frontiers in aging neuroscience (28-05-2021)“…The antidepressant drug amitriptyline is used in the treatment of clinical depression and a variety of neurological conditions such as anxiety, neuropathic…”
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Chronic, low-dose prenatal exposure to methylmercury impairs motor and mnemonic function in adult C57/B6 mice
Published in Behavioural brain research (05-08-2008)“…Methylmercury (MeHg) has cytotoxic effects on animals and humans, and a major target organ for MeHg is the central nervous system (CNS). It is well known that…”
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Prefrontal cortical-striatal dopamine receptor mRNA expression predicts distinct forms of impulsivity
Published in The European journal of neuroscience (01-06-2013)“…Variation in dopamine receptor levels has been associated with different facets of impulsivity. To further delineate the neural substrates underlying impulsive…”
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Molecular, physiological and behavioral characterization of the heterozygous Df[h15q13]/+ mouse model associated with the human 15q13.3 microdeletion syndrome
Published in Brain research (01-11-2020)“…•In a heterozygous 15q13.3 mouse model α7 nAChR binding sites are reduced by half.•Heterozygous mice show deficits in spatial learning in the Barnes…”
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Good things come to those who wait: Attenuated discounting of delayed rewards in aged Fischer 344 rats
Published in Neurobiology of aging (01-05-2010)“…Abstract The ability to make advantageous choices among outcomes that differ in magnitude, probability, and delay until their arrival is critical for optimal…”
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Effects of ethanol and varenicline on female Sprague-Dawley rats in a third trimester model of fetal alcohol syndrome
Published in Alcohol (Fayetteville, N.Y.) (01-09-2018)“…Perinatal ethanol exposure disrupts a variety of developmental processes in neurons important for establishing a healthy brain. These ethanol-induced…”
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Deficits in hippocampal-dependent transfer generalization learning accompany synaptic dysfunction in a mouse model of amyloidosis
Published in Hippocampus (01-04-2016)“…ABSTRACT Elevated β‐amyloid and impaired synaptic function in hippocampus are among the earliest manifestations of Alzheimer's disease (AD). Most cognitive…”
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Long-term effects of prior cocaine exposure on Morris water maze performance
Published in Neurobiology of learning and memory (01-02-2008)“…Cocaine addiction is associated with long-term cognitive alterations including deficits on tests of declarative/spatial learning and memory. To determine the…”
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Altered spatial learning and delay discounting in a rat model of human third trimester binge ethanol exposure
Published in Behavioural pharmacology (01-02-2012)“…Ethanol exposure during perinatal development can cause cognitive abnormalities including difficulties in learning, attention, and memory, as well as…”
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Novel age-dependent learning deficits in a mouse model of Alzheimer's disease: Implications for translational research
Published in Alzheimer's & dementia (01-07-2009)Get full text
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Cognitive changes and circadian timekeeping disturbances in aging
Published in Alzheimer's & dementia (01-12-2022)“…Background Cognitive changes in aging and Alzheimer’s disease (AD) are often accompanied by pronounced disturbances of circadian timekeeping, especially…”
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TARGETING PRE-DEMENTIA SYNAPTIC MECHANISMS DURING AGING AND COGNITIVE IMPAIRMENT
Published in Alzheimer's & dementia (01-07-2017)Get full text
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Brain-derived neurotrophic factor promotes adaptive plasticity within the spinal cord and mediates the beneficial effects of controllable stimulation
Published in Neuroscience (03-01-2012)“…Abstract Brain-derived neurotrophic factor (BDNF) has been characterized as a potent modulator of neural plasticity in both the brain and spinal cord. The…”
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Prefrontal cortical–striatal dopamine receptor m RNA expression predicts distinct forms of impulsivity
Published in The European journal of neuroscience (01-06-2013)“…Abstract Variation in dopamine receptor levels has been associated with different facets of impulsivity. To further delineate the neural substrates underlying…”
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P4‐037: Novel age‐dependent learning deficits in a mouse model of Alzheimer's disease: Implications for translational research
Published in Alzheimer's & dementia (01-07-2009)Get full text
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