Search Results - "Montes Aparicio, Claudia N"

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    Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol by Kerr, Matthew, Miller, Jack J, Thapa, Dharendra, Stiewe, Sophie, Timm, Kerstin N, Aparicio, Claudia N Montes, Scott, Iain, Tyler, Damian J, Heather, Lisa C

    Published in JCI insight (03-09-2020)
    “…Cardiac energetic dysfunction has been reported in patients with type 2 diabetes (T2D) and is an independent predictor of mortality. Identification of the…”
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    Journal Article
  2. 2

    Activation of HIF1α Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart by Sousa Fialho, Maria da Luz, Purnama, Ujang, Dennis, Kaitlyn M J H, Montes Aparicio, Claudia N, Castro-Guarda, Marcos, Massourides, Emmanuelle, Tyler, Damian J, Carr, Carolyn A, Heather, Lisa C

    Published in Diabetes (New York, N.Y.) (01-11-2021)
    “…Type 2 diabetes (T2D) impairs hypoxia-inducible factor (HIF)1α activation, a master transcription factor that drives cellular adaptation to hypoxia. Reduced…”
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    Positioning Metabolism as a Central Player in the Diabetic Heart by Mereweather, Laura J., Montes Aparicio, Claudia N., Heather, Lisa C.

    “…In type 2 diabetes (T2D), the leading cause of death is cardiovascular complications. One mechanism contributing to cardiac pathogenesis is alterations in…”
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    A trishistidine pseudopeptide with ability to remove both Cui and Cuii from the amyloid-β peptide and to stop the associated ROS formation by Conte-Daban, A., Boff, B., Candido Matias, A., Aparicio, C. N. Montes, Gateau, C., Lebrun, C., Cerchiaro, G., Kieffer, I., Sayen, S., Guillon, E., Delangle, P., Hureau, C.

    Published in Chemistry : a European journal (01-12-2017)
    “…The pseudopeptide L , derived from a nitrilotriacetic acid scaffold and functionalized with three histidine moieties, is reminiscent of the amino acid side…”
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