Search Results - "Montes, Marcela"

Hookworm Secreted Extracellular Vesicles Interact With Host Cells and Prevent Inducible Colitis in Mice by Eichenberger, Ramon M, Ryan, Stephanie, Jones, Linda, Buitrago, Geraldine, Polster, Ramona, Montes de Oca, Marcela, Zuvelek, Jennifer, Giacomin, Paul R, Dent, Lindsay A, Engwerda, Christian R, Field, Matthew A, Sotillo, Javier, Loukas, Alex

“…Gastrointestinal (GI) parasites, hookworms in particular, have evolved to cause minimal harm to their hosts, allowing them to establish chronic infections…”
Get full text

Type I Interferons Regulate Immune Responses in Humans with Blood-Stage Plasmodium falciparum Infection by Montes de Oca, Marcela, Kumar, Rajiv, Rivera, Fabian de Labastida, Amante, Fiona H., Sheel, Meru, Faleiro, Rebecca J., Bunn, Patrick T., Best, Shannon E., Beattie, Lynette, Ng, Susanna S., Edwards, Chelsea L., Boyle, Glen M., Price, Ric N., Anstey, Nicholas M., Loughland, Jessica R., Burel, Julie, Doolan, Denise L., Haque, Ashraful, McCarthy, James S., Engwerda, Christian R.

“…The development of immunoregulatory networks is important to prevent disease. However, these same networks allow pathogens to persist and reduce vaccine…”
Get full text

The Impact of Established Immunoregulatory Networks on Vaccine Efficacy and the Development of Immunity to Malaria by Montes de Oca, Marcela, Good, Michael F, McCarthy, James S, Engwerda, Christian R

“…The development of vaccines to protect against parasites is difficult, in large part due to complex host-parasite interactions that have evolved over…”
Get full text

Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology by Montes de Oca, Marcela, Kumar, Rajiv, de Labastida Rivera, Fabian, Amante, Fiona H, Sheel, Meru, Faleiro, Rebecca J, Bunn, Patrick T, Best, Shannon E, Beattie, Lynette, Ng, Susanna S, Edwards, Chelsea L, Muller, Werner, Cretney, Erika, Nutt, Stephen L, Smyth, Mark J, Haque, Ashraful, Hill, Geoffrey R, Sundar, Shyam, Kallies, Axel, Engwerda, Christian R

“…Tumor necrosis factor (TNF) is critical for controlling many intracellular infections, but can also contribute to inflammation. It can promote the destruction…”
Get full text

IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection by Montes de Oca, Marcela, de Labastida Rivera, Fabian, Winterford, Clay, Frame, Teija C M, Ng, Susanna S, Amante, Fiona H, Edwards, Chelsea L, Bukali, Luzia, Wang, Yulin, Uzonna, Jude E, Kuns, Rachel D, Zhang, Ping, Kabat, Agnieszka, Klein Geltink, Ramon I, Pearce, Edward J, Hill, Geoffrey R, Engwerda, Christian R

“…Inflammation is critical for controlling pathogens, but also responsible for symptoms of infectious diseases. IL-27 is an important regulator of inflammation…”
Get full text

STING activation promotes autologous type I interferon–dependent development of type 1 regulatory T cells during malaria by Wang, Yulin, De Labastida Rivera, Fabian, Edwards, Chelsea L, Frame, Teija C.M, Engel, Jessica A, Bukali, Luzia, Na, Jinrui, Ng, Susanna S, Corvino, Dillon, de Oca, Marcela Montes, Bunn, Patrick T, Soon, Megan S.F, Andrew, Dean, Loughland, Jessica R, Zhang, Jia, Amante, Fiona H, Barber, Bridget E, McCarthy, James S, Lopez, J. Alejandro, Boyle, Michelle J, Engwerda, Christian R

“…The development of highly effective malaria vaccines and improvement of drug- treatment protocols to boost antiparasitic immunity are critical for malaria…”
Get full text

IL-10-producing Th1 cells possess a distinct molecular signature in malaria by Edwards, Chelsea L, Ng, Susanna S, de Labastida Rivera, Fabian, Corvino, Dillon, Engel, Jessica A, Montes de Oca, Marcela, Bukali, Luzia, Frame, Teija Cm, Bunn, Patrick T, Chauhan, Shashi Bhushan, Singh, Siddharth Sankar, Wang, Yulin, Na, Jinrui, Amante, Fiona H, Loughland, Jessica R, Soon, Megan Sf, Waddell, Nicola, Mukhopadhay, Pamela, Koufariotis, Lambros T, Johnston, Rebecca L, Lee, Jason S, Kuns, Rachel, Zhang, Ping, Boyle, Michelle J, Hill, Geoffrey R, McCarthy, James S, Kumar, Rajiv, Engwerda, Christian R

Get full text

IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection by Sebina, Ismail, James, Kylie R, Soon, Megan S F, Fogg, Lily G, Best, Shannon E, Labastida Rivera, Fabian de, Montes de Oca, Marcela, Amante, Fiona H, Thomas, Bryce S, Beattie, Lynette, Souza-Fonseca-Guimaraes, Fernando, Smyth, Mark J, Hertzog, Paul J, Hill, Geoffrey R, Hutloff, Andreas, Engwerda, Christian R, Haque, Ashraful

“…Parasite-specific antibodies protect against blood-stage Plasmodium infection. However, in malaria-endemic regions, it takes many months for naturally-exposed…”
Get full text

Plasmacytoid dendritic cells appear inactive during sub-microscopic Plasmodium falciparum blood-stage infection, yet retain their ability to respond to TLR stimulation by Loughland, Jessica R., Minigo, Gabriela, Sarovich, Derek S., Field, Matt, Tipping, Peta E., Montes de Oca, Marcela, Piera, Kim A., Amante, Fiona H., Barber, Bridget E., Grigg, Matthew J., William, Timothy, Good, Michael F., Doolan, Denise L., Engwerda, Christian R., Anstey, Nicholas M., McCarthy, James S., Woodberry, Tonia

“…Plasmacytoid dendritic cells (pDC) are activators of innate and adaptive immune responses that express HLA-DR, toll-like receptor (TLR) 7, TLR9 and produce…”
Get full text

"Ripping Off the Band-Aid": uncovering future health care Professionals' "Fractured Knowledge" about sexual and reproductive health by Mejia, Angie, Nyhus, Kara, Burley, Tessie, Myhre, Alexis, Montes, Marcela, Osiecki, Kristin, Randolph, Anita C

“…Research has shown the role of identity on future health professionals' confidence and competence in addressing the sexual and reproductive health (SRH) needs…”
Get full text

A molecular signature for IL-10-producing Th1 cells in protozoan parasitic diseases by Edwards, Chelsea L, Engel, Jessica A, de Labastida Rivera, Fabian, Ng, Susanna S, Corvino, Dillon, Montes de Oca, Marcela, Frame, Teija Cm, Chauhan, Shashi Bhushan, Singh, Siddharth Sankar, Kumar, Awnish, Wang, Yulin, Na, Jinrui, Mukhopadhyay, Pam, Lee, Jason S, Nylen, Susanne, Sundar, Shyam, Kumar, Rajiv, Engwerda, Christian R

“…Control of visceral leishmaniasis (VL) depends on proinflammatory Th1 cells that activate infected tissue macrophages to kill resident intracellular parasites…”
Get full text

Combined Immune Therapy for the Treatment of Visceral Leishmaniasis by Faleiro, Rebecca J, Kumar, Rajiv, Bunn, Patrick T, Singh, Neetu, Chauhan, Shashi Bhushan, Sheel, Meru, Amante, Fiona H, Montes de Oca, Marcela, Edwards, Chelsea L, Ng, Susanna S, Best, Shannon E, Haque, Ashraful, Beattie, Lynette, Hafner, Louise M, Sacks, David, Nylen, Susanne, Sundar, Shyam, Engwerda, Christian R

“…Chronic disease caused by infections, cancer or autoimmunity can result in profound immune suppression. Immunoregulatory networks are established to prevent…”
Get full text

The Role of BACH2 in T Cells in Experimental Malaria Caused by Plasmodium chabaudi chabaudi AS by Edwards, Chelsea L, de Oca, Marcela Montes, de Labastida Rivera, Fabian, Kumar, Rajiv, Ng, Susanna S, Wang, Yulin, Amante, Fiona H, Kometani, Kohei, Kurosaki, Tomohiro, Sidwell, Tom, Kallies, Axel, Engwerda, Christian R

“…BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 2 (BACH2) is a transcription factor best known for its role in B cell development. More…”
Get full text

Galectin-1 Impairs the Generation of Anti-Parasitic Th1 Cell Responses in the Liver during Experimental Visceral Leishmaniasis by Bunn, Patrick T, Montes de Oca, Marcela, Rivera, Fabian de Labastida, Kumar, Rajiv, Edwards, Chelsea L, Faleiro, Rebecca J, Ng, Susanna S, Sheel, Meru, Wang, Yulin, Amante, Fiona H, Haque, Ashraful, Engwerda, Christian R

“…Many infectious diseases are characterized by the development of immunoregulatory pathways that contribute to pathogen persistence and associated disease…”
Get full text

Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection by Ng, Susanna S, Souza‐Fonseca‐Guimaraes, Fernando, Rivera, Fabian de Labastida, Amante, Fiona H, Kumar, Rajiv, Gao, Yulong, Sheel, Meru, Beattie, Lynette, Montes de Oca, Marcela, Guillerey, Camille, Edwards, Chelsea L, Faleiro, Rebecca J, Frame, Teija, Bunn, Patrick T, Vivier, Eric, Godfrey, Dale I, Pellicci, Daniel G, Lopez, J Alejandro, Andrews, Katherine T, Huntington, Nicholas D, Smyth, Mark J, McCarthy, James, Engwerda, Christian R

“…Objectives Innate lymphoid cells (ILCs) share many characteristics with CD4+ T cells, and group 1 ILCs share a requirement for T‐bet and the ability to produce…”
Get full text

The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation by Ng, Susanna S., De Labastida Rivera, Fabian, Yan, Juming, Corvino, Dillon, Das, Indrajit, Zhang, Ping, Kuns, Rachel, Chauhan, Shashi Bhushan, Hou, Jiajie, Li, Xian-Yang, Frame, Teija C. M., McEnroe, Benjamin A., Moore, Eilish, Na, Jinrui, Engel, Jessica A., Soon, Megan S. F., Singh, Bhawana, Kueh, Andrew J., Herold, Marco J., Montes de Oca, Marcela, Singh, Siddharth Sankar, Bunn, Patrick T., Aguilera, Amy Roman, Casey, Mika, Braun, Matthias, Ghazanfari, Nazanin, Wani, Shivangi, Wang, Yulin, Amante, Fiona H., Edwards, Chelsea L., Haque, Ashraful, Dougall, William C., Singh, Om Prakash, Baxter, Alan G., Teng, Michele W. L., Loukas, Alex, Daly, Norelle L., Cloonan, Nicole, Degli-Esposti, Mariapia A., Uzonna, Jude, Heath, William R., Bald, Tobias, Tey, Siok-Keen, Nakamura, Kyohei, Hill, Geoffrey R., Kumar, Rajiv, Sundar, Shyam, Smyth, Mark J., Engwerda, Christian R.

“…Immune-modulating therapies have revolutionized the treatment of chronic diseases, particularly cancer. However, their success is restricted and there is a…”
Get full text

Early reduction in PD-L1 expression predicts faster treatment response in human cutaneous leishmaniasis by Dey, Nidhi S, Senaratne, Sujai, Somaratne, Vijani, Madarasinghe, Nayani P, Seneviratne, Bimalka, Forrester, Sarah, Montes de Oca, Marcela, Reis, Luiza Campos, Moulik, Srija, Walrad, Pegine B, Chatterjee, Mitali, Goto, Hiro, Wickremasinghe, Renu, Lagos, Dimitris, Kaye, Paul M, Ranasinghe, Shalindra

Get full text

Early reduction in PD-L1 expression predicts faster treatment response in human cutaneous leishmaniasis by Dey, Nidhi S, Senaratne, Sujai, Somaratne, Vijani, Madarasinghe, Nayani P, Seneviratne, Bimalka, Forrester, Sarah, Montes de Oca, Marcela, Reis, Luiza Campos, Moulik, Srija, Walrad, Pegine B, Chatterjee, Mitali, Goto, Hiro, Wickremasinghe, Renu, Lagos, Dimitris, Kaye, Paul M, Ranasinghe, Shalindra

“…Cutaneous leishmaniasis (CL) is caused by Leishmania donovani in Sri Lanka. Pentavalent antimonials (e.g., sodium stibogluconate [SSG]) remain first-line drugs…”
Get full text

Distinct Roles for CD4 + Foxp3 + Regulatory T Cells and IL-10-Mediated Immunoregulatory Mechanisms during Experimental Visceral Leishmaniasis Caused by Leishmania donovani by Bunn, Patrick T, Montes de Oca, Marcela, de Labastida Rivera, Fabian, Kumar, Rajiv, Ng, Susanna S, Edwards, Chelsea L, Faleiro, Rebecca J, Sheel, Meru, Amante, Fiona H, Frame, Teija C M, Muller, Werner, Haque, Ashraful, Uzonna, Jude E, Hill, Geoffrey R, Engwerda, Christian R

“…The outcome of intracellular parasitic infection can be determined by the immunoregulatory activities of natural regulatory CD4 Foxp3 T (Treg) cells and the…”
Get full text

Human IL-10–producing Th1 cells exhibit a molecular signature distinct from Tr1 cells in malaria by Edwards, Chelsea L, Ng, Susanna S, Rivera, Fabian de Labastida, Corvino, Dillon, Engel, Jessica A, de Oca, Marcela Montes, Bukali, Luzia, Frame, Teija C.M, Bunn, Patrick T, Chauhan, Shashi Bhushan, Singh, Siddharth Sankar, Wang, Yulin, Na, Jinrui, Amante, Fiona H, Loughland, Jessica R, Soon, Megan S.F, Waddell, Nicola, Mukhopadhay, Pamela, Koufariotis, Lambros T, Johnston, Rebecca L, Lee, Jason S, Kuns, Rachel, Zhang, Ping, Boyle, Michelle J, Hill, Geoffrey R, McCarthy, James S, Kumar, Rajiv, Engwerda, Christian R

“…Control of intracellular parasites responsible for malaria requires host IFN-[[gamma].sup.+]T-[bet.sup.+][CD4.sup.+] T cells (Th1 cells) with IL-10 produced by…”
Get full text