Search Results - "Montero, Jose A."
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First-in-human evaluation of [11C]PS13, a novel PET radioligand, to quantify cyclooxygenase-1 in the brain
Published in European journal of nuclear medicine and molecular imaging (01-12-2020)“…Purpose This study assessed whether the newly developed PET radioligand [ 11 C]PS13, which has shown excellent in vivo selectivity in previous animal studies,…”
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Influence of age at first calving in a continuous calving season on productive, functional, and economic performance in a Blonde d'Aquitaine beef population
Published in Journal of animal science (29-09-2018)“…The lifetime production of 7,655 cows with known age at first calving and a total of 27,118 parity records from 301 purebred Blonde d'Aquitaine herds were used…”
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3
Cardiac differentiation is driven by NKX2.5 and GATA4 nuclear translocation in tissue-specific mesenchymal stem cells
Published in Stem cells and development (01-07-2009)“…Myocardial infarction is a major public health problem that causes significant mortality despite recent advances in its prevention and treatment. Therefore,…”
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Whole-Body PET Imaging in Humans Shows That 11C-PS13 Is Selective for Cyclooxygenase-1 and Can Measure the In Vivo Potency of Nonsteroidal Antiinflammatory Drugs
Published in The Journal of nuclear medicine (1978) (01-01-2023)“…Both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) convert arachidonic acid to prostaglandin H2, which has proinflammatory effects. The recently…”
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5
2-(4-Methylsulfonylphenyl)pyrimidines as Prospective Radioligands for Imaging Cyclooxygenase-2 with PET-Synthesis, Triage, and Radiolabeling
Published in Molecules (Basel, Switzerland) (02-11-2018)“…Cyclooxygenase 2 (COX-2) is an inducible enzyme responsible for the conversion of arachidonic acid into the prostaglandins, PGG2 and PGH2. Expression of this…”
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In Vivo Evaluation of 6 Analogs of 11C-ER176 as Candidate 18F-Labeled Radioligands for 18-kDa Translocator Protein
Published in The Journal of nuclear medicine (1978) (01-08-2022)“…Because of its excellent ratio of specific to nondisplaceable uptake, the radioligand 11C-ER176 can successfully image 18-kDa translocator protein (TSPO), a…”
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Atypical Cat Scratch Disease with Hepatosplenic Involvement
Published in Clinical gastroenterology and hepatology (01-01-2017)Get full text
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Region- and voxel-based quantification in human brain of [18F]LSN3316612, a radioligand for O-GlcNAcase
Published in EJNMMI research (01-04-2021)“…Background Previous studies found that the positron emission tomography (PET) radioligand [ 18 F]LSN3316612 accurately quantified O -GlcNAcase in human brain…”
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PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study
Published in Journal of neuroinflammation (02-05-2020)“…Cyclooxygenase-2 (COX-2), which is rapidly upregulated by inflammation, is a key enzyme catalyzing the rate-limiting step in the synthesis of several…”
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10
Prognostic value of chronic obstructive pulmonary disease in coronary artery bypass grafting
Published in European journal of cardio-thoracic surgery (01-02-2006)“…Objective: Coronary and chronic lung diseases have become a common association. This comorbidity has been generically considered by most of the operative risk…”
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Discovery of a High-Affinity Fluoromethyl Analog of [11C]5-Cyano-N-(4-(4-methylpiperazin-1-yl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide ([11C]CPPC) and Their Comparison in Mouse and Monkey as Colony-Stimulating Factor 1 Receptor Positron Emission Tomography Radioligands
Published in ACS pharmacology & translational science (14-04-2023)“…[11C]CPPC has been advocated as a radioligand for colony-stimulating factor 1 receptor (CSF1R) with the potential for imaging neuroinflammation in human…”
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12
Purification process development for HER1 extracellular domain as a potential therapeutic vaccine
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-10-2009)“…HER1 is a tumor associated antigen emerging as an attractive target for cancer therapy. In the present study we demonstrated for first time that HER1…”
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13
A comparison of electrospun polymers reveals poly(3-hydroxybutyrate) fiber as a superior scaffold for cardiac repair
Published in Stem cells and development (01-07-2014)“…The development of biomaterials for myocardial tissue engineering requires a careful assessment of their performance with regards to functionality and…”
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14
Whole-Body PET Imaging in Humans Shows That 11 C-PS13 Is Selective for Cyclooxygenase-1 and Can Measure the In Vivo Potency of Nonsteroidal Antiinflammatory Drugs
Published in Journal of Nuclear Medicine (01-01-2023)“…Both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) convert arachidonic acid to prostaglandin H , which has proinflammatory effects. The recently…”
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Journal Article -
15
In Vivo Evaluation of 6 Analogs of 11 C-ER176 as Candidate 18 F-Labeled Radioligands for 18-kDa Translocator Protein
Published in Journal of Nuclear Medicine (01-08-2022)“…Because of its excellent ratio of specific to nondisplaceable uptake, the radioligand C-ER176 can successfully image 18-kDa translocator protein (TSPO), a…”
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16
Developing a videogame for learning signal processing and project management using project-oriented learning in ICT engineering degrees
Published in Computers in human behavior (01-10-2019)“…This work describes the design, implementation and evaluation of a multi-subject learning experience based on the principles of Constructionism, in which the…”
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First-in-Human Evaluation of 18 F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B
Published in Journal of Nuclear Medicine (01-12-2022)“…Phosphodiesterase-4 (PDE4), which metabolizes the second messenger cyclic adenosine monophosphate (cAMP), has 4 isozymes: PDE4A, PDE4B, PDE4C, and PDE4D. PDE4B…”
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The Proof-of-Concept of MBA121, a Tacrine-Ferulic Acid Hybrid, for Alzheimer's Disease Therapy
Published in International journal of molecular sciences (31-07-2023)“…Great effort has been devoted to the synthesis of novel multi-target directed tacrine derivatives in the search of new treatments for Alzheimer's disease (AD)…”
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First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B
Published in The Journal of nuclear medicine (1978) (01-12-2022)“…Phosphodiesterase-4 (PDE4), which metabolizes the second messenger cyclic adenosine monophosphate (cAMP), has 4 isozymes: PDE4A, PDE4B, PDE4C, and PDE4D. PDE4B…”
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20
Genotype FBN1/phenotype relationship in a cohort of patients with Marfan syndrome
Published in Clinical genetics (01-02-2021)“…Marfan syndrome (MFS) is a systemic connective tissue disorder caused by mutations in the fibrillin‐1 (FBN1) gene, and cardiovascular involvement is the…”
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