Search Results - "Montemurro, F"

Trastuzumab: mechanism of action, resistance and future perspectives in HER2-overexpressing breast cancer by Valabrega, G, Montemurro, F, Aglietta, M

“…Trastuzumab is a humanized mAb directed against the extracellular domain of the tyrosine kinase receptor HER2. Trastuzumab has shown clinical activity in…”
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Human epidermal growth factor receptor 2 (HER2)-positive and hormone receptor-positive breast cancer: new insights into molecular interactions and clinical implications by Montemurro, F., Di Cosimo, S., Arpino, G.

“…Recent data show a significant benefit from combining an anti-HER-2 agent with endocrine therapy in HER2-positive and hormone receptor (HR)-positive metastatic…”
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Trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer and brain metastases: exploratory final analysis of cohort 1 from KAMILLA, a single-arm phase IIIb clinical trial by Montemurro, F., Delaloge, S., Barrios, C.H., Wuerstlein, R., Anton, A., Brain, E., Hatschek, T., Kelly, C.M., Peña-Murillo, C., Yilmaz, M., Donica, M., Ellis, P.

“…Patients with brain metastases (BM) from human epidermal growth factor receptor 2 (HER2)-positive breast cancer represent a difficult-to-treat population…”
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Active immunotherapy in HER2 overexpressing breast cancer: current status and future perspectives by Milani, A., Sangiolo, D., Montemurro, F., Aglietta, M., Valabrega, G.

“…The use of anti-HER2 monoclonal antibodies (mAbs) has improved the clinical outcome of HER2-overexpressing breast cancers (BCs). Unfortunately, often these…”
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How do novel and conventional agri-food wastes, co-products and by-products improve soil functions and soil quality? by Gebremikael, M.T., Ranasinghe, A., Hosseini, P.S., Laboan, B., Sonneveld, E., Pipan, M., Oni, F.E., Montemurro, F., Höfte, M., Sleutel, S., De Neve, S.

“…•Low value agri-food wastes, co-products and by-products (AFWCBs) improve soil quality.•Insect frass residues suppress plant disease, increase microbial…”
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Metastatic breast cancer subtypes and central nervous system metastases by Aversa, C, Rossi, V, Geuna, E, Martinello, R, Milani, A, Redana, S, Valabrega, G, Aglietta, M, Montemurro, F

“…Abstract Background Breast cancer (BC) subtypes have different survival and response to therapy. We studied predictors of central nervous system metastases…”
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Safety of everolimus plus exemestane in patients with hormone-receptor–positive, HER2–negative locally advanced or metastatic breast cancer progressing on prior non-steroidal aromatase inhibitors: primary results of a phase IIIb, open-label, single-arm, expanded-access multicenter trial (BALLET) by Jerusalem, G., Mariani, G., Ciruelos, E.M., Martin, M., Tjan-Heijnen, V.C.G., Neven, P., Gavila, J.G., Michelotti, A., Montemurro, F., Generali, D., Simoncini, E., Lang, I., Mardiak, J., Naume, B., Camozzi, M., Lorizzo, K., Bianchetti, S., Conte, P.

“…This European phase IIIb, expanded-access multicenter trial evaluated the safety of EVE plus EXE in a patient population similar to BOLERO-2. Post-menopausal…”
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Comprehensive mapping review of real-world evidence publications focusing on targeted therapies in solid tumors: A collaborative work from ESMO real-world data and Digital Health Working Group by Pellat, A., Grinda, T., Prelaj, A., Cresta, P., Valachis, A, Zerdes, I., Branco, D. Martins, Provenzano, L., Spagnoletti, A., Marta, G. Nader, Wilson, B., Montemurro, F., Castelo-Branco, L., Pentheroudakis, G., Delaloge, S., Koopman, M.

“…Background : A growing body of real-world evidence (RWE) aims to better reflect outcomes of cancer patients treated in real-world settings. We aimed to conduct…”
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Oral etoposide in heavily pre-treated metastatic breast cancer: A retrospective series by Giannone, G., Milani, A., Ghisoni, E., Genta, S., Mittica, G., Montemurro, F., Valabrega, G.

“…Patients with metastatic breast cancer (MBC) can derive clinical benefit from several subsequent lines of chemotherapy. However, in heavily pre-treated…”
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Energy flows in European organic vegetable systems: Effects of the introduction and management of agroecological service crops by Navarro-Miró, D., Iocola, I., Persiani, A., Blanco-Moreno, J.M., Kristensen, H. Lakkenborg, Hefner, M., Tamm, K., Bender, I., Védie, H., Willekens, K., Diacono, M., Montemurro, F., Sans, F.X., Canali, S.

“…Reducing inputs by promoting the recycling of energy within a cropping system is one of the principles of organic farming. To this end, the introduction and…”
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Tracking the blue: A MLST approach to characterise the Pseudomonas fluorescens group by Andreani, N.A., Martino, M.E., Fasolato, L., Carraro, L., Montemurro, F., Mioni, R., Bordin, P., Cardazzo, B.

“…The Pseudomonas fluorescens group comprises several closely related species that are involved in food contamination and spoilage. Specifically, the interest in…”
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Complications of hyperglycaemia with PI3K–AKT–mTOR inhibitors in patients with advanced solid tumours on Phase I clinical trials by Geuna, E, Roda, D, Rafii, S, Jimenez, B, Capelan, M, Rihawi, K, Montemurro, F, Yap, T A, Kaye, S B, De Bono, J S, Molife, L R, Banerji, U

“…Background: PI3K–AKT–mTOR inhibitors (PAMi) are promising anticancer treatments. Hyperglycaemia is a mechanism-based toxicity of these agents and is becoming…”
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Organic amendment and minimum tillage in winter wheat grown in Mediterranean conditions: Effects on yield performance, soil fertility and environmental impact by Debiase, G., Montemurro, F., Fiore, A., Rotolo, C., Farrag, K., Miccolis, A., Brunetti, G.

“…•The minimum tillage allowed to reach the some production of traditional one.•Sewage sludge treatment reached yield performance similar to mineral fertilizer…”
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Oral etoposide in heavily pretreated metastatic breast cancer: a retrospective analysis of efficacy and safety by Giannone, G, Milani, A, Ghisoni, E, Genta, S, Mittica, G, Montemurro, F, Valabrega, G

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Changes in Labile Fractions of Soil Organic Matter During the Conversion to Organic Farming by Abdelrahman, H., Cocozza, C., Olk, D. C., Ventrella, D., Montemurro, F., Miano, T.

“…Organic farming can overcome the environmental consequences of intensive conventional farming. The objective of the work was to investigate the changes in…”
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HER2-positive metastatic breast cancer: A changing scenario by Mustacchi, G, Biganzoli, L, Pronzato, P, Montemurro, F, Dambrosio, M, Minelli, M, Molteni, L, Scaltriti, L

“…Abstract Adjuvant trastuzumab (AT) dramatically improved HER2-positive breast cancer prognosis. Relapsed disease after AT has different patterns and…”
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Enhancing multifunctional benefits of living mulch in organic vegetable cropping systems by Canali, S., Diacono, M., Montemurro, F., Delate, K.

“…Over the last several decades, agriculture in industrialized countries experienced a significant intensification as a result of the diffusion of mechanization,…”
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Nitrogen indicators, uptake and utilization efficiency in a maize and barley rotation cropped at different levels and sources of N fertilization by Montemurro, F., Maiorana, M., Ferri, D., Convertini, G.

“…A 3-year experiment was carried out in Mediterranean conditions on two maize–barley rotations to determine the effect of different levels and sources of…”
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Discontinuation rate and serious adverse events of chemoimmunotherapy as neoadjuvant treatment for triple-negative breast cancer: a systematic review and meta-analysis by Rizzo, A, Schipilliti, F M, Di Costanzo, F, Acquafredda, S, Arpino, G, Puglisi, F, Del Mastro, L, Montemurro, F, De Laurentiis, M, Giuliano, M

“…The use of combination of chemotherapy with immune checkpoint inhibitors (ICIs) has shown efficacy in triple-negative breast cancer (TNBC), and…”
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Pathological non-response to chemotherapy in a neoadjuvant setting of breast cancer: an inter-institutional study by Balmativola, D., Marchiò, C., Maule, M., Chiusa, L., Annaratone, L., Maletta, F., Montemurro, F., Kulka, J., Figueiredo, P., Varga, Z., Liepniece-Karele, I., Cserni, G., Arkoumani, E., Amendoeira, I., Callagy, G., Reiner-Concin, A., Cordoba, A., Bianchi, S., Decker, T., Gläser, D., Focke, C., van Diest, P., Grabau, D., Lips, E., Wesseling, J., Arisio, R., Medico, E., Wells, C., Sapino, A.

“…To identify markers of non-response to neoadjuvant chemotherapy (NAC) that could be used in the adjuvant setting. Sixteen pathologists of the European Working…”
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