Search Results - "Montell, Denise"

Cell motility in cancer invasion and metastasis: insights from simple model organisms by Stuelten, Christina H., Parent, Carole A., Montell, Denise J.

“…Key Points The motility of both tumour and normal host cells contributes to tumour metastasis at several steps, including breaching of basement membrane,…”
Get full text

Morphogenetic Cell Movements: Diversity from Modular Mechanical Properties by Montell, Denise J

“…Animal tissue and organ development requires the orchestration of cell movements, including those of interconnected cell groups, termed collective cell…”
Get full text

Mechanical Feedback through E-Cadherin Promotes Direction Sensing during Collective Cell Migration by Cai, Danfeng, Chen, Shann-Ching, Prasad, Mohit, He, Li, Wang, Xiaobo, Choesmel-Cadamuro, Valerie, Sawyer, Jessica K., Danuser, Gaudenz, Montell, Denise J.

“…E-cadherin is a major homophilic cell-cell adhesion molecule that inhibits motility of individual cells on matrix. However, its contribution to migration of…”
Get full text

Macrophages, masters of invasion by Montell, Denise J.

“…Macrophages are exceptionally invasive cells. In a recent article in Science, Akhmanova et al. describe a novel mechanism facilitating macrophage infiltration…”
Get full text

Apoptotic signaling: Beyond cell death by Nano, Maddalena, Montell, Denise J.

“…Apoptosis is the best described form of regulated cell death, and was, until relatively recently, considered irreversible once particular biochemical…”
Get full text

The molecular mechanisms of diapause and diapause-like reversible arrest by Easwaran, Sreesankar, Montell, Denise J

“…Diapause is a protective mechanism that many organisms deploy to overcome environmental adversities. Diapause extends lifespan and fertility to enhance the…”
Get more information

Development and dynamics of cell polarity at a glance by Campanale, Joseph P, Sun, Thomas Y, Montell, Denise J

“…Cells exhibit morphological and molecular asymmetries that are broadly categorized as cell polarity. The cell polarity established in early embryos prefigures…”
Get full text

Unconventional Ways to Live and Die: Cell Death and Survival in Development, Homeostasis, and Disease by Gudipaty, Swapna A, Conner, Christopher M, Rosenblatt, Jody, Montell, Denise J

“…Balancing cell death and survival is essential for normal development and homeostasis and for preventing diseases, especially cancer. Conventional cell death…”
Get full text

Integration of Migratory Cells into a New Site In Vivo Requires Channel-Independent Functions of Innexins on Microtubules by Miao, Guangxia, Godt, Dorothea, Montell, Denise J.

“…During embryonic development and cancer metastasis, migratory cells must establish stable connections with new partners at their destinations. Here, we…”
Get full text

Nuclear lamin facilitates collective border cell invasion into confined spaces in vivo by Penfield, Lauren, Montell, Denise J

“…Cells migrate collectively through confined environments during development and cancer metastasis. The nucleus, a stiff organelle, impedes single cells from…”
Get full text

Editorial: Special issue SCDB “Cell death and survival”: Cell death and resilience in health and disease by Nano, Maddalena, Montell, Denise J.

Get full text

Border cell polarity and collective migration require the spliceosome component Cactin by Miao, Guangxia, Guo, Li, Montell, Denise J

“…Border cells are an in vivo model for collective cell migration. Here, we identify the gene cactin as essential for border cell cluster organization,…”
Get full text

EMT, One of Many Morphological Transitions in Cellular Phase Space by Montell, Denise J

“…The epithelial to mesenchymal transition (EMT) is an enticingly simple mechanism that converts stationary epithelial cells into migratory mesenchymal cells…”
Get more information

TRIMing Neural Connections with Ubiquitin by Montell, Denise J.

“…During evolution, ubiquitin ligases increased in number with increasing nervous system complexity. Recent work shows that proper brain development, cognitive…”
Get full text

Group choreography: mechanisms orchestrating the collective movement of border cells by Montell, Denise J., Yoon, Wan Hee, Starz-Gaiano, Michelle

“…Key Points Cell movement is essential for animal development, homeostasis and disease progression. Some cells move in groups, others as single cells…”
Get full text

Tissue elongation requires oscillating contractions of a basal actomyosin network by He, Li, Montell, Denise J, Tang, Ho Lam, Wang, Xiaobo

“…Oscillating activities of actomyosin networks at the apical side of epithelial cells have been linked to morphogenesis in Drosophila . Montell and colleagues…”
Get full text

Rab11 regulates cell–cell communication during collective cell movements by Ramel, Damien, Wang, Xiaobo, Laflamme, Carl, Montell, Denise J., Emery, Gregory

“…Emery and colleagues show that during collective migration of Drosophila border cells, the Rab11 small GTPase regulates Rac activity throughout the cell…”
Get full text

Cell survival following direct executioner-caspase activation by Nano, Maddalena, Mondo, James A, Harwood, Jacob, Balasanyan, Varuzhan, Montell, Denise J

“…Executioner-caspase activation has been considered a point-of-no-return in apoptosis. However, numerous studies report survival from caspase activation after…”
Get full text

Q&A: Cellular near death experiences-what is anastasis? by Sun, Gongping, Montell, Denise J

“…Apoptosis is a form of programmed cell death that is carried out by proteolytic enzymes called caspases. Executioner caspase activity causes cells to shrink,…”
Get full text

Cell interactions in collective cell migration by Mishra, Abhinava K., Campanale, Joseph P., Mondo, James A., Montell, Denise J.

“…ABSTRACT Collective cell migration is the coordinated movement of a physically connected group of cells and is a prominent driver of development and…”
Get full text