Search Results - "Monteiro Longo, Beatriz"
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Resistance Exercise Decreases Amyloid Load and Modulates Inflammatory Responses in the APP/PS1 Mouse Model for Alzheimer's Disease
Published in Journal of Alzheimer's disease (01-01-2020)“…Neuroinflammation has been shown to play a crucial role in the development of Alzheimer's disease (AD) and also has an association with amyloid-β (Aβ) plaques,…”
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Modification of pre-ictal cortico-hippocampal oscillations by medial ganglionic eminence precursor cells grafting in the pilocarpine model of epilepsy
Published in Epilepsy & behavior (01-10-2024)“…Cell replacement therapies using medial ganglionic eminence (MGE)-derived GABAergic precursors reduce seizures by restoring inhibition in animal models of…”
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The effects of resistance exercise on cognitive function, amyloidogenesis, and neuroinflammation in Alzheimer's disease
Published in Frontiers in neuroscience (02-03-2023)“…With the increasing prevalence of Alzheimer's disease (AD) and difficulties in finding effective treatments, it is essential to discover alternative therapies…”
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Behavioral changes resulting from the administration of cycloheximide in the pilocarpine model of epilepsy
Published in Brain research (20-12-2005)“…Cycloheximide influences synaptic reorganization resulting from pilocarpine-induced status epilepticus (SE). To investigate the possible behavioral…”
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Neuroprotective effects of resistance physical exercise on the APP/PS1 mouse model of Alzheimer's disease
Published in Frontiers in neuroscience (06-04-2023)“…Physical exercise has beneficial effects by providing neuroprotective and anti-inflammatory responses to AD. Most studies, however, have been conducted with…”
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Clozapine prevented social interaction deficits and reduced c-Fos immunoreactivity expression in several brain areas of rats exposed to acute restraint stress
Published in PloS one (03-03-2022)“…In the present study, we evaluate the effect of acute restraint stress (15 min) of male Wistar rats on social interaction measurements and c-Fos…”
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Therapeutic effects of the transplantation of VEGF overexpressing bone marrow mesenchymal stem cells in the hippocampus of murine model of Alzheimer's disease
Published in Frontiers in aging neuroscience (07-03-2014)“…Alzheimer's disease (AD) is clinically characterized by progressive memory loss, behavioral and learning dysfunction and cognitive deficits, such as…”
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Bradykinin promotes immune responses in differentiated embryonic neurospheres carrying APPswe and PS1dE9 mutations
Published in Cell & bioscience (18-06-2024)“…Neural progenitor cells (NPCs) can be cultivated from developing brains, reproducing many of the processes that occur during neural development. They can be…”
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The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-Driven Brain Tumor
Published in PloS one (12-06-2015)“…Glioblastoma (GBM) is an infiltrative tumor that is difficult to eradicate. Treating GBM with mesenchymal stem cells (MSCs) that have been modified with the…”
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Atypical antipsychotic olanzapine reversed deficit on prepulse inhibition of the acoustic startle reflex produced by microinjection of dizocilpine (MK-801) into the inferior colliculus in rats
Published in Behavioural brain research (15-11-2013)“…•Unilateral microinjections of MK-801, an NMDA antagonist, into the inferior colliculus (IC) disrupted PPI.•Microinjections of NMDA into the IC did not alter…”
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Maternal deprivation alters growth, food intake, and neuropeptide Y in the hypothalamus of adolescent male and female rats
Published in Developmental psychobiology (01-12-2016)“…Maternal deprivation (MD) for 24 hr during the neonatal period impairs body weight gain in adolescent and adult rats. It has been previously shown that…”
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Transplantation of inhibitory precursor cells from medial ganglionic eminence produces distinct responses in two different models of acute seizure induction
Published in Epilepsy & behavior (01-05-2017)“…Abstract Medial ganglionic eminence (MGE) is one of the sources of inhibitory interneurons during development. Following transplantation in postnatal…”
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Effect of the bone marrow cell transplantation on elevated plus-maze performance in hippocampal-injured mice
Published in Behavioural brain research (01-07-2013)“…•Electrolytic lesion in mice dorsal hippocampus induced behavioral disinhibition.•Cell transplantation provided a discreet relief in the injury-induced…”
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Manganese-enhanced magnetic resonance imaging in the acute phase of the pilocarpine-induced model of epilepsy
Published in Einstein (São Paulo, Brazil) (01-06-2012)“…Magnetic resonance images are useful in the study of experimental models of temporal lobe epilepsy. The manganese-enhanced MRI (MEMRI) technique is of interest…”
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Purinergic signaling in cognitive impairment and neuropsychiatric symptoms of Alzheimer's disease
Published in Neuropharmacology (15-03-2023)“…About 10 million new cases of dementia develop worldwide each year, of which up to 70% are attributable to Alzheimer's disease (AD). In addition to the widely…”
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Bradykinin promotes immune responses in differentiated embryonic neurospheres carrying APP swe and PS1 dE9 mutations
Published in Cell & bioscience (18-06-2024)“…Neural progenitor cells (NPCs) can be cultivated from developing brains, reproducing many of the processes that occur during neural development. They can be…”
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Intravenous infusion of bone marrow mononuclear cells promotes functional recovery and improves impaired cognitive function via inhibition of Rho guanine nucleotide triphosphatases and inflammatory signals in a model of chronic epilepsy
Published in Brain structure & function (01-12-2020)“…Temporal lobe epilepsy is the most common form of intractable epilepsy in adults. More than 30% of individuals with epilepsy have persistent seizures and have…”
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AAV-mediated neuronal expression of an scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models
Published in Molecular therapy (01-02-2023)“…The accumulation of soluble oligomers of the amyloid-β peptide (AβOs) in the brain has been implicated in synapse failure and memory impairment in Alzheimer’s…”
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Manganese-Enhanced MRI: Biological Applications in Neuroscience
Published in Frontiers in neurology (10-07-2015)“…Magnetic resonance imaging (MRI) is an excellent non-invasive tool to investigate biological systems. The administration of the paramagnetic divalent ion…”
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Distinct Effects of the Hippocampal Transplantation of Neural and Mesenchymal Stem Cells in a Transgenic Model of Alzheimer's Disease
Published in Stem cell reviews and reports (01-02-2022)“…Alzheimer's disease (AD) is a severe disabling condition with no cure currently available, which accounts for 60-70% of all dementia cases worldwide…”
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