Search Results - "Monteiro, Wuelton"
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Malaria in Brazil, Colombia, Peru and Venezuela: current challenges in malaria control and elimination
Published in Malaria journal (04-07-2017)“…In spite of significant progress towards malaria control and elimination achieved in South America in the 2000s, this mosquito-transmitted tropical disease…”
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Building an explanatory model for snakebite envenoming care in the Brazilian Amazon from the indigenous caregivers' perspective
Published in PLoS neglected tropical diseases (01-03-2023)“…In the Brazilian Amazon, snakebite envenomings (SBE) disproportionately affect indigenous peoples. Communication between indigenous and biomedical health…”
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Poor efficacy of preemptive amoxicillin clavulanate for preventing secondary infection from Bothrops snakebites in the Brazilian Amazon: A randomized controlled clinical trial
Published in PLoS neglected tropical diseases (10-07-2017)“…Secondary bacterial infections from snakebites contribute to the high complication rates that can lead to permanent function loss and disabilities. Although…”
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Evaluation of a point-of-care diagnostic to identify glucose-6-phosphate dehydrogenase deficiency in Brazil
Published in PLoS neglected tropical diseases (01-08-2021)“…Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common enzyme deficiency, prevalent in many malaria-endemic countries. G6PD-deficient…”
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Snakebite envenomations and access to treatment in communities of two indigenous areas of the Western Brazilian Amazon: A cross-sectional study
Published in PLoS neglected tropical diseases (01-07-2023)“…The indigenous populations of Brazil present poor health indicators and a disproportionate prevalence and case-fatality rate of neglected tropical diseases,…”
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Development and validation of a minimum requirements checklist for snakebite envenoming treatment in the Brazilian Amazonia
Published in PLoS neglected tropical diseases (01-01-2024)“…Currently, antivenoms are the only specific treatment available for snakebite envenoming. In Brazil, over 30% of patients cannot access antivenom within its…”
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Real-life quantitative G6PD screening in Plasmodium vivax patients in the Brazilian Amazon: A cost-effectiveness analysis
Published in PLoS neglected tropical diseases (01-03-2022)“…As quantitative glucose 6-phosphate dehydrogenase deficiency (G6PDd) screening tools are evaluated in operational studies, questions remain as to whether they…”
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Estimated impact of tafenoquine for Plasmodium vivax control and elimination in Brazil: A modelling study
Published in PLoS medicine (23-04-2021)“…Despite recent intensification of control measures, Plasmodium vivax poses a major challenge for malaria elimination efforts. Liver-stage hypnozoite parasites…”
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Impact of piperaquine resistance in Plasmodium falciparum on malaria treatment effectiveness in The Guianas: a descriptive epidemiological study
Published in The Lancet infectious diseases (01-02-2024)“…Plasmodium falciparum is an apicomplexan parasite responsible for lethal cases of malaria. According to WHO recommendations, P falciparum cases are treated…”
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Urinary proteomics reveals biological processes related to acute kidney injury in Bothrops atrox envenomings
Published in PLoS neglected tropical diseases (01-03-2024)“…Acute kidney injury (AKI) is a critical systemic complication caused by Bothrops envenoming, a neglected health problem in the Brazilian Amazon. Understanding…”
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Tafenoquine following G6PD screening versus primaquine for the treatment of vivax malaria in Brazil: A cost-effectiveness analysis using a transmission model
Published in PLoS medicine (09-01-2024)“…Malaria transmission modelling has demonstrated the potential impact of semiquantitative glucose-6-phosphate dehydrogenase (G6PD) testing and treatment with…”
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Morphological and Transcriptional Changes in Human Bone Marrow During Natural Plasmodium vivax Malaria Infections
Published in The Journal of infectious diseases (01-04-2022)“…Abstract Background The presence of Plasmodium vivax malaria parasites in the human bone marrow (BM) is still controversial. However, recent data from a…”
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Spatial distribution of G6PD deficiency variants across malaria-endemic regions
Published in Malaria journal (15-11-2013)“…Primaquine is essential for malaria control and elimination since it is the only available drug preventing multiple clinical attacks by relapses of Plasmodium…”
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High proportions of asymptomatic and submicroscopic Plasmodium vivax infections in a peri-urban area of low transmission in the Brazilian Amazon
Published in Parasites & vectors (20-03-2018)“…Population-based studies conducted in Latin America have shown a high proportion of asymptomatic and submicroscopic malarial infections. Considering efforts…”
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Clinical Spectrum of Primaquine-induced Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficiency: A 9-Year Hospitalization-based Study From the Brazilian Amazon
Published in Clinical infectious diseases (27-09-2019)“…Despite glucose-6-phosphate dehydrogenase (G6PD) deficiency prevalence of 5% in the Amazon, primaquine is administered without G6PD screening. This is an…”
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Expression levels of pvcrt-o and pvmdr-1 are associated with chloroquine resistance and severe Plasmodium vivax malaria in patients of the Brazilian Amazon
Published in PloS one (26-08-2014)“…Molecular markers associated with the increase of chloroquine resistance and disease severity in Plasmodium vivax are needed. The objective of this study was…”
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Development and validation of serological markers for detecting recent Plasmodium vivax infection
Published in Nature Medicine (01-05-2020)“…A major gap in the Plasmodium vivax elimination toolkit is the identification of individuals carrying clinically silent and undetectable liver-stage parasites,…”
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Plasma metabolomics reveals membrane lipids, aspartate/asparagine and nucleotide metabolism pathway differences associated with chloroquine resistance in Plasmodium vivax malaria
Published in PloS one (16-08-2017)“…Chloroquine (CQ) is the main anti-schizontocidal drug used in the treatment of uncomplicated malaria caused by Plasmodium vivax. Chloroquine resistant P. vivax…”
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Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile
Published in PLoS neglected tropical diseases (06-04-2017)“…The presence of P. vivax in the bone marrow was first noticed in the late 19th century [2], and examinations of sternal bone marrow aspirates were performed as…”
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Accelerating towards P. vivax elimination with a novel serological test-and-treat strategy: a modelling case study in Brazil
Published in Lancet Regional Health - Americas (Online) (01-06-2023)“…Plasmodium vivax malaria is challenging to control and eliminate. Treatment with radical cure drugs fails to target the hidden asymptomatic and hypnozoite…”
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