Search Results - "Monteiro, R.Q"

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    Epidermal growth factor receptor regulates fibrinolytic pathway elements in cervical cancer: functional and prognostic implications by Gomes, F G, Almeida, V H, Martins-Cardoso, K, Martins-Dinis, M M D C, Rondon, A M R, Melo, A C de, Tilli, T M, Monteiro, R Q

    “…Epidermal growth factor receptor (EGFR) signaling and components of the fibrinolytic system, including urokinase-type plasminogen activator (uPA) and…”
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    The tick‐derived inhibitor Ixolaris prevents tissue factor signaling on tumor cells by CARNEIRO‐LOBO, T. C., SCHAFFNER, F., DISSE, J., OSTERGAARD, H., FRANCISCHETTI, I. M. B., MONTEIRO, R. Q., RUF, W.

    Published in Journal of thrombosis and haemostasis (01-09-2012)
    “…Summary  Background:  Tissue factor (TF) is frequently overexpressed in cancer cells and correlated with more aggressive tumor phenotypes and poor prognosis…”
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    Ixolaris, a tissue factor inhibitor, blocks primary tumor growth and angiogenesis in a glioblastoma model by CARNEIRO‐LOBO, T. C., KONIG, S., MACHADO, D. E., NASCIUTTI, L. E., FORNI, M. F., FRANCISCHETTI, I. M. B., SOGAYAR, M. C., MONTEIRO, R. Q.

    Published in Journal of thrombosis and haemostasis (01-11-2009)
    “…Background: The expression levels of the clotting initiator protein Tissue Factor (TF) correlate with vessel density and the histological malignancy grade of…”
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    On the molecular mechanisms for the highly procoagulant pattern of C6 glioma cells by FERNANDES, R. S., KIRSZBERG, C., RUMJANEK, V. M., MONTEIRO, R. Q.

    Published in Journal of thrombosis and haemostasis (01-07-2006)
    “…Background: That there is a correlation between cancer and procoagulant states is well‐known. C6 glioma cell line was originally induced in random‐bred…”
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    Increased expression of tissue factor and protease-activated receptor-1 does not correlate with thrombosis in human lung adenocarcinoma by de Meis, E, Azambuja, D, Ayres-Silva, J P, Zamboni, M, Pinheiro, V R, Levy, R A, Monteiro, R Q

    “…A correlation between cancer and hypercoagulability has been described for more than a century. Patients with cancer are at increased risk for thrombotic…”
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    Procoagulant properties of human MV3 melanoma cells by Geaquinto, D L A, Fernandes, R S, Lima, L G, Barja-Fidalgo, C, Monteiro, R Q

    “…A correlation between cancer and prothrombotic states has long been described. More recently, a number of studies have focused on the procoagulant mechanisms…”
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    Structural Basis for the Interaction of Human β-Defensin 6 and Its Putative Chemokine Receptor CCR2 and Breast Cancer Microvesicles by De Paula, V.S., Gomes, N.S.F., Lima, L.G., Miyamoto, C.A., Monteiro, R.Q., Almeida, F.C.L., Valente, A.P.

    Published in Journal of molecular biology (15-11-2013)
    “…Human β-defensins (hBDs) are believed to function as alarm molecules that stimulate the adaptive immune system when a threat is present. In addition to its…”
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    Recombinant expression of Ixolaris, a Kunitz-type inhibitor from the tick salivary gland, for NMR studies by De Paula, V.S., Silva, F.H.S., Francischetti, I.M.B., Monteiro, R.Q., Valente, A.P.

    Published in Protein expression and purification (01-11-2017)
    “…Ixolaris is an anticoagulant protein identified in the tick saliva of Ixodes scapularis. Ixolaris contains 2 Kunitz like domains and binds to Factor Xa or…”
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