Search Results - "Monteiro, Hugo P"

Protein tyrosine phosphorylation and protein tyrosine nitration in redox signaling by Monteiro, Hugo P, Arai, Roberto J, Travassos, Luiz R

“…Reversible phosphorylation of protein tyrosine residues by polypeptide growth factor-receptor protein tyrosine kinases is implicated in the control of…”
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Thioredoxin promotes survival signaling events under nitrosative/oxidative stress associated with cancer development by Monteiro, Hugo P, Ogata, Fernando T, Stern, Arnold

“…Accumulating mutations may drive cells into the acquisition of abnormal phenotypes that are characteristic of cancer cells. Cancer cells feature profound…”
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17Beta-Estradiol Induces the Translocation of the Estrogen Receptors ESR1 and ESR2 to the Cell Membrane, MAPK3/1 Phosphorylation and Proliferation of Cultured Immature Rat Sertoli Cells by Lucas, Thaís F.G, Siu, Erica R, Esteves, Carlos A, Monteiro, Hugo P, Oliveira, Cleida A, Porto, Catarina S, Lazari, Maria Fatima M

“…The aim of the present study was to determine the mechanisms involved in estrogen actions in cultured rat Sertoli cells. RT-PCR detected transcripts for the…”
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Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth by Paschoalin, Thaysa, Carmona, Adriana K, Rodrigues, Elaine G, Oliveira, Vitor, Monteiro, Hugo P, Juliano, Maria A, Juliano, Luiz, Travassos, Luiz R

“…Angiogenesis is a fundamental process that allows tumor growth by providing nutrients and oxygen to the tumor cells. Beyond the oxygen diffusion limit from a…”
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Nitric oxide and cGMP activate the Ras-MAP kinase pathway-stimulating protein tyrosine phosphorylation in rabbit aortic endothelial cells by Oliveira, Carlos J.R, Schindler, Fernanda, Ventura, Armando M, Morais, Miriam S, Arai, Roberto J, Debbas, Victor, Stern, Arnold, Monteiro, Hugo P

“…The free radical nitric oxide is a very effective signal transducer, stimulating the enzyme guanylyl cyclase, the oncoprotein p21Ras, and protein tyrosine…”
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Nitric oxide and interactions with reactive oxygen species in the development of melanoma, breast, and colon cancer: A redox signaling perspective by Monteiro, Hugo P., Rodrigues, Elaine G., Amorim Reis, Adriana K.C., Longo, Luiz S., Ogata, Fernando T., Moretti, Ana I.S., da Costa, Paulo E., Teodoro, Ana C.S., Toledo, Maytê S., Stern, Arnold

“…Cancer development is closely related to chronic inflammation, which is associated with identifiable markers of tumor progression, such as uncontrolled cell…”
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Serum amyloid A induces CCL20 secretion in mononuclear cells through MAPK (p38 and ERK1/2) signaling pathways by Sandri, Silvana, Hatanaka, Elaine, Franco, Andressa G, Pedrosa, Alziana M.C, Monteiro, Hugo P, Campa, Ana

“…Abstract Although the serum levels of SAA had been reported to be upregulated during inflammatory/infectious process, the role of this acute-phase protein has…”
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Macrophages, IL-10, and nitric oxide increase, induced by hyperglycemic conditions, impact the development of murine melanoma B16F10-Nex2 by Sellani, Tarciso A., Tomaz, Samanta L., Gonçalves, Jéssica M., Lima, Adriana, de Amat Herbozo, Carolina C., Silva, Gabrielli N., Gambero, Mônica, Longo-Maugéri, Ieda M., Simon, Karin A., Monteiro, Hugo P., Rodrigues, Elaine G.

“…Epidemiological studies show a strong correlation between diabetes and the increased risk of developing different cancers, including melanoma. In the present…”
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Bradykinin promotes murine melanoma cell migration and invasion through endogenous production of superoxide and nitric oxide by Eller-Borges, Roberta, Rodrigues, Elaine G., Teodoro, Ana Caroline S., Moraes, Miriam S., Arruda, Denise C., Paschoalin, Thaysa, Curcio, Marli F., da Costa, Paulo E., Do Nascimento, Igor R., Calixto, Leandro A., Stern, Arnold, Monteiro, Hugo P., Batista, Wagner L.

“…Spatial confinement and temporal regulation of signaling by nitric oxide (NO) and reactive oxygen species (ROS) occurs in cancer cells. Signaling mediated by…”
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Endothelium-derived nitric oxide (NO) activates the NO-epidermal growth factor receptor-mediated signaling pathway in bradykinin-stimulated angiogenesis by Moraes, Miriam S., Costa, Paulo E., Batista, Wagner L., Paschoalin, Taysa, Curcio, Marli F., Borges, Roberta E., Taha, Murched O., Fonseca, Fábio V., Stern, Arnold, Monteiro, Hugo P.

“…•The NO–EGF-R signaling pathway was studied in endothelial cells stimulated with bradykinin.•Bradykinin promotes tyrosine phosphorylation and cysteine…”
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Knockdown of the inducible nitric oxide synthase (NOS2) splicing variant S3 promotes autophagic cell death from nitrosative stress in SW480 human colon cancer cells by Castro, Eloisa D., Mathias, Pedro Paulo M., Batista, Wagner L., Sato, Alex Yuri S., Toledo, Maytê S., Almeida, Victor T., Curcio, Marli F., Costa, Paulo E., Stern, Arnold, Monteiro, Hugo P.

“…Low levels of nitric oxide (NO) produced by constitutively expressed inducible NO synthase (NOS2) in tumor cells may be an important factor in their…”
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17Beta-Estradiol Induces the Translocation of the Estrogen Receptors ESR1 and ESR2 to the Cell Membrane, MAPK3/1 Phosphorylation and Proliferation of Cultured Immature Rat Sertoli Cells1 by Lucas, Thaís F. G, Siu, Erica R, Esteves, Carlos A, Monteiro, Hugo P, Oliveira, Cleida A, Porto, Catarina S, Lazari, Maria Fatima M

“…The aim of the present study was to determine the mechanisms involved in estrogen actions in cultured rat Sertoli cells. RT-PCR detected transcripts for the…”
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Nitric oxide stimulates a PKC-Src-Akt signaling axis which increases human immunodeficiency virus type 1 replication in human T lymphocytes by Curcio, Marli F., Batista, Wagner L., Castro, Eloísa D., Strumillo, Scheilla T., Ogata, Fernando T., Alkmim, Wagner, Brunialti, Milena K.C., Salomão, Reinaldo, Turcato, Gilberto, Diaz, Ricardo S., Monteiro, Hugo P., Janini, Luiz Mário R.

“…Human immunodeficiency virus (HIV) infections are typically accompanied by high levels of secreted inflammatory cytokines and generation of high levels of…”
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Heparan sulfate proteoglycan deficiency up‐regulates the intracellular production of nitric oxide in Chinese hamster ovary cell lines by Lucena, Sheyla V., Moura, Gioconda E. D. D., Rodrigues, Tiago, Watashi, Carolina M., Melo, Fabiana H., Icimoto, Marcelo Y., Viana, Gustavo M., Nader, Helena B., Monteiro, Hugo P., Tersariol, Ivarne L. S., Ogata, Fernando T.

“…We investigated the role of glycosaminoglycans (GAGs) in the regulation of endothelial nitric oxide synthase (eNOS) activity in wild‐type CHO‐K1 cells and in…”
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Basal neutrophil function in human aging: Implications in endothelial cell adhesion by Nogueira-Neto, Joes, Cardoso, André S. C., Monteiro, Hugo P., Fonseca, Fernando L. A., Ramos, Luiz Roberto, Junqueira, Virginia B. C., Simon, Karin A.

“…Much attention has been drawn to the pro‐inflammatory condition that accompanies aging. This study compared parameters from non‐stimulated neutrophils,…”
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S-nitrosoglutathione and endothelial nitric oxide synthase-derived nitric oxide regulate compartmentalized ras S-nitrosylation and stimulate cell proliferation by Batista, Wagner L, Ogata, Fernando T, Curcio, Marli F, Miguel, Rodrigo B, Arai, Roberto J, Matsuo, Alisson L, Moraes, Miriam S, Stern, Arnold, Monteiro, Hugo P

“…S-nitrosylation of Cys118 is a redox-based mechanism for Ras activation mediated by nitric oxide (NO) at the plasma membrane. Ras signaling pathway stimulation…”
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Nitric oxide: Protein tyrosine phosphorylation and protein S-nitrosylation in cancer by Monteiro, Hugo P, Costa, Paulo E, Reis, Adriana K C A, Stern, Arnold

“…Cancer is a worldwide health problem leading to a high incidence of morbidity and mortality. Malignant transformation can occur by expression of oncogenes,…”
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Signal transduction by protein tyrosine nitration: competition or cooperation with tyrosine phosphorylation-dependent signaling events? by Monteiro, Hugo P

“…This review article is an attempt to stimulate a discussion on the significance of protein tyrosine nitration to cellular signaling and its relationships with…”
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The Ig VH complementarity-determining region 3-containing Rb9 peptide, inhibits melanoma cells migration and invasion by interactions with Hsp90 and an adhesion G-protein coupled receptor by Girola, Natalia, Matsuo, Alisson L., Figueiredo, Carlos R., Massaoka, Mariana H., Farias, Camyla F., Arruda, Denise C., Azevedo, Ricardo A., Monteiro, Hugo P., Resende-Lara, Pedro T., Cunha, Rodrigo L.O.R., Polonelli, Luciano, Travassos, Luiz R.

“…•Rb9 is a flexible, hairpin forming, cyclic peptide, with an exposed disulfide bridge.•Rb9 but not the analogous linear Rb10, forms an α–helix stabilized by…”
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Ras, Rac1, and phosphatidylinositol-3-kinase (PI3K) signaling in nitric oxide induced endothelial cell migration by Eller-Borges, Roberta, Batista, Wagner L., da Costa, Paulo E., Tokikawa, Rita, Curcio, Marli F., Strumillo, Scheilla T., Sartori, Adriano, Moraes, Miriam S., de Oliveira, Graciele A., Taha, Murched O., Fonseca, Fábio V., Stern, Arnold, Monteiro, Hugo P.

“…•BK stimulates NO production, activates Rac and stimulates cell migration.•NO promotes the interaction between Ras and PI3K.•NO-mediated Rac activation…”
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