Search Results - "Montavon, Donna K."

A General Method for Palladium-Catalyzed Reactions of Primary Sulfonamides with Aryl Nonaflates by Shekhar, Shashank, Dunn, Travis B, Kotecki, Brian J, Montavon, Donna K, Cullen, Steven C

“…A general method for Pd-catalyzed sulfonamidation of aryl nonafluorobutanesulfonates (aryl nonaflates) is described. A biaryl phosphine ligand, t-BuXPhos,…”
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Discovery and Development of Metal-Catalyzed Coupling Reactions in the Synthesis of Dasabuvir, an HCV-Polymerase Inhibitor by Barnes, David M, Shekhar, Shashank, Dunn, Travis B, Barkalow, Jufang H, Chan, Vincent S, Franczyk, Thaddeus S, Haight, Anthony R, Hengeveld, John E, Kolaczkowski, Lawrence, Kotecki, Brian J, Liang, Guangxin, Marek, James C, McLaughlin, Maureen A, Montavon, Donna K, Napier, James J

“…Dasabuvir (1) is an HCV polymerase inhibitor which has been developed as a part of a three-component direct-acting antiviral combination therapy. During the…”
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Discovery and Hit-to-Lead Optimization of Non-ATP Competitive MK2 (MAPKAPK2) Inhibitors by Huang, Xiaohua, Shipps, Gerald W., Cheng, Cliff C., Spacciapoli, Peter, Zhang, Xingmin, McCoy, Mark A., Wyss, Daniel F., Yang, Xianshu, Achab, Abdelghani, Soucy, Kyle, Montavon, Donna K., Murphy, Denise M., Whitehurst, Charles E.

“…A novel series of non-ATP-competitive MK2 inhibitors based on a furan-2-carboxyamide scaffold was discovered through high-throughput screening using the…”
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