Efficacy and tolerance of a five days course of ciprofloxacin in the treatment of urinary tract infection in women

Background: There is no consensus about the ideal antimicrobial agent and duration of treatment for urinary tract infection in women. Aim: To assess the efficacy of a five days course of ciprofloxacin for the treatment of urinary tract infection in women. Patients and methods: Women with urinary tra...

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Bibliographic Details
Published in:	Revista medíca de Chile Vol. 126; no. 1; pp. 49 - 55
Main Authors:	Prado, V J, Haristoy, J C, Montano, R V, Castrillon, M G, Sepulveda, S M, Zemelman, R Z, Flaskamp, RvF, Martinez, J D, Cumsille, F G
Format:	Journal Article
Language:	English Spanish
Published:	01-01-1998
Online Access:	Get full text
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Summary:	Background: There is no consensus about the ideal antimicrobial agent and duration of treatment for urinary tract infection in women. Aim: To assess the efficacy of a five days course of ciprofloxacin for the treatment of urinary tract infection in women. Patients and methods: Women with urinary tract infection were treated with ciprofloxacin (Baycip registered , Bayer) 250 mg bid during 5 days. Patients were evaluated three to four days after treatment start, two to seven days and one month after treatment end. Results: Of 101 eligible women, 96 aged 18 to 65 years old, coming from three major Chilean cities, participated in the study and 80 completed the follow up period. There was a 95% clinical success, 2.5% partial improvement and 2.5% treatment failure. The causal microorganism was eradicated in 90% of cases, in 1.2% treatment failed and in 8.7% a re-infection occurred. Adverse effects attributable to the drug were observed in 12 patients (headache in 3, gastrointestinal disturbances in 8, somnolence in 1 and irritability in 1). Conclusions: Ciprofloxacin is an useful antimicrobial for the treatment of lower urinary tract infection in women.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23
ISSN:	0034-9887