Search Results - "Montano, Giorgia"

KRAB-Zinc Finger Proteins: A Repressor Family Displaying Multiple Biological Functions by Lupo, Angelo, Cesaro, Elena, Montano, Giorgia, Zurlo, Diana, Izzo, Paola, Costanzo, Paola

“…Zinc finger proteins containing the Kruppel associated box (KRAB-ZFPs) constitute the largest individual family of transcriptional repressors encoded by the…”
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Enhanced protein synthesis is a defining requirement for neonatal B cell development by Åkerstrand, Hugo, Boldrin, Elena, Montano, Giorgia, Vanhee, Stijn, Olsson, Karin, Krausse, Niklas, Vergani, Stefano, Cieśla, Maciej, Bellodi, Cristian, Yuan, Joan

“…The LIN28B RNA binding protein exhibits an ontogenically restricted expression pattern and is a key molecular regulator of fetal and neonatal B lymphopoiesis…”
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Distinct global binding patterns of the Wilms tumor gene 1 (WT1) -KTS and +KTS isoforms in leukemic cells by Ullmark, Tove, Järvstråt, Linnea, Sandén, Carl, Montano, Giorgia, Jernmark-Nilsson, Helena, Lilljebjörn, Henrik, Lennartsson, Andreas, Fioretos, Thoas, Drott, Kristina, Vidovic, Karina, Nilsson, Björn, Gullberg, Urban

“…The zinc finger transcription factor Wilms tumor gene 1 (WT1) acts as an oncogene in acute myeloid leukemia. A naturally occurring alternative splice event…”
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KAP1 is a Novel Substrate for the Arginine Methyltransferase PRMT5 by di Caprio, Roberta, Ciano, Michela, Montano, Giorgia, Costanzo, Paola, Cesaro, Elena

“…KRAB-associated protein 1 (KAP1), the transcriptional corepressor of Kruppel-associated box zinc finger proteins (KRAB-ZFPs), is subjected to multiple…”
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DNA and RNA binding by the Wilms' tumour gene 1 (WT1) protein +KTS and −KTS isoforms—From initial observations to recent global genomic analyses by Ullmark, Tove, Montano, Giorgia, Gullberg, Urban

“…The Wilms' tumour gene 1 protein (WT1) is a zinc finger transcription factor found indispensable for foetal development. WT1 has also been implicated in the…”
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A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut by Vergani, Stefano, Muleta, Konjit Getachew, Da Silva, Clément, Doyle, Alexander, Kristiansen, Trine Ahn, Sodini, Selene, Krausse, Niklas, Montano, Giorgia, Kotarsky, Knut, Nakawesi, Joy, Åkerstrand, Hugo, Vanhee, Stijn, Gupta, Sneh Lata, Bryder, David, Agace, William Winston, Lahl, Katharina, Yuan, Joan

“…The adult immune system consists of cells that emerged at various times during ontogeny. We aimed to define the relationship between developmental origin and…”
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Anti-apoptotic quinolinate phosphoribosyltransferase (QPRT) is a target gene of Wilms' tumor gene 1 (WT1) protein in leukemic cells by Ullmark, Tove, Montano, Giorgia, Järvstråt, Linnea, Jernmark Nilsson, Helena, Håkansson, Erik, Drott, Kristina, Nilsson, Björn, Vidovic, Karina, Gullberg, Urban

“…Wilms' tumor gene 1 (WT1) is a zinc finger transcription factor that has been implicated as an oncogene in leukemia and several other malignancies. When…”
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Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia by Sodaro, Gaetano, Cesaro, Elena, Montano, Giorgia, Blasio, Giancarlo, Fiorentino, Federica, Romano, Simona, Jacquel, Arnaud, Aurberger, Patrick, Costanzo, Paola

“…The transcription factor ZNF224 plays a key proapoptotic role in chronic myelogenous leukemia (CML), by modulating Wilms Tumor protein 1 (WT1) dependent…”
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Role of WT1-ZNF224 interaction in the expression of apoptosis-regulating genes by Montano, Giorgia, Cesaro, Elena, Fattore, Luigi, Vidovic, Karina, Palladino, Chiara, Crescitelli, Rossella, Izzo, Paola, Turco, Maria Caterina, Costanzo, Paola

“…The transcription factor Wilms' tumor gene 1, WT1, is implicated both in normal developmental processes and in the generation of a variety of solid tumors and…”
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DNA and RNA binding by the Wilms' tumour gene 1 (WT1) protein +KTS and -KTS isoforms-From initial observations to recent global genomic analyses by Ullmark, Tove, Montano, Giorgia, Gullberg, Urban

“…The Wilms' tumour gene 1 protein (WT1) is a zinc finger transcription factor found indispensable for foetal development. WT1 has also been implicated in the…”
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ZNF224: Structure and role of a multifunctional KRAB-ZFP protein by Lupo, Angelo, Cesaro, Elena, Montano, Giorgia, Izzo, Paola, Costanzo, Paola

“…The Kruppel-like zinc finger protein ZNF224 was originally identified as the transcriptional repressor of the human aldolase A gene. ZNF224 transcriptional…”
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The hematopoietic tumor suppressor interferon regulatory factor 8 (IRF8) is upregulated by the antimetabolite cytarabine in leukemic cells involving the zinc finger protein ZNF224, acting as a cofactor of the Wilms’ tumor gene 1 (WT1) protein by Montano, Giorgia, Ullmark, Tove, Jernmark-Nilsson, Helena, Sodaro, Gaetano, Drott, Kristina, Costanzo, Paola, Vidovic, Karina, Gullberg, Urban

“…Highlights • The cytostatic drug cytarabine induces the tumor suppressor IRF8 in leukemic cells. • The effect of cytarabine is dependent on the zinc-finger…”
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Abstract 2005: Global binding pattern of the Wilms’ tumor gene 1 (WT1) +17AA -KTS isoform in leukemic cells by Ullmark, Tove, Järvstråt, Linnea, Montano, Giorgia, Jernmark-Nilsson, Helena, Sandén, Carl, Nilsson, Björn, Vidovic, Karina, Gullberg, Urban

“…Abstract The aim of this study was to investigate the global DNA-binding pattern of Wilms’ tumor gene 1 (WT1) in leukemic cells. Clinical and preclinical data…”
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Distinct global binding patterns of the Wilms tumor gene 1 (WT1) -KTS and plus KTS isoforms in leukemic cells by Ullmark, T, Jarvstrat, L, Sanden, C, Montano, G, Jernmark-Nilsson, H, Lilljebjorn, H, Lennartsson, A, Fioretos, T, Drott, K, Vidovic, K

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WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene by Montano, Giorgia, Vidovic, Karina, Palladino, Chiara, Cesaro, Elena, Sodaro, Gaetano, Quintarelli, Concetta, De Angelis, Biagio, Errichiello, Santa, Pane, Fabrizio, Izzo, Paola, Grosso, Michela, Gullberg, Urban, Costanzo, Paola

“…The Kruppel-like protein ZNF224 is a co-factor of the Wilms' tumor 1 protein, WT1. We have previously shown that ZNF224 exerts a specific proapoptotic role in…”
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Biochemical and functional interaction between ZNF224 and ZNF255, two members of the Krüppel-like zinc-finger protein family and WT1 protein isoforms by Florio, Francesca, Cesaro, Elena, Montano, Giorgia, Izzo, Paola, Miles, Colin, Costanzo, Paola

“…Wilms' tumour suppressor gene, WT1, is mutated/deleted in ∼15% of Wilms' tumours, highly expressed in the majority of other cancers and is essential for normal…”
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The transcriptional coregulator NAB2 is a target gene for the Wilms' tumor gene 1 protein (WT1) in leukemic cells by Nilsson, Helena Jernmark, Montano, Giorgia, Ullmark, Tove, Lennartsson, Andreas, Drott, Kristina, Järvstråt, Linnea, Nilsson, Björn, Vidovic, Karina, Gullberg, Urban

“…The Wilms' tumor gene 1 ( ) is recurrently mutated in acute myeloid leukemia. Mutations and high expression of associate with a poor prognosis. In mice, WT1…”
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Biochemical and functional interaction between ZNF224 and ZNF255, two members of the Krueppel-like zinc-finger protein family and WT1 protein isoforms by Florio, Francesca, Cesaro, Elena, Montano, Giorgia, Izzo, Paola, Miles, Colin, Costanzo, Paola

“…Wilms' tumour suppressor gene, WT1, is mutated/deleted in 615% of Wilms' tumours, highly expressed in the majority of other cancers and is essential for normal…”
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Global binding pattern of the Wilms' tumor gene 1 (WT1) +17AA -KTS isoform in leukemic cells by Ullmark, Tove, Järvstråt, Linnea, Montano, Giorgia, Jernmark-Nilsson, Helena, Sandén, Carl, Vidovic, Karina, Gullberg, Urban

“…The aim of this study was to investigate the global DNA-binding pattern of Wilms' tumor gene 1 (WT1) in leukemic cells. Clinical and preclinical data indicate…”
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