Search Results - "Montaner, Luis J"

Cytokine storm and leukocyte changes in mild versus severe SARS‐CoV‐2 infection: Review of 3939 COVID‐19 patients in China and emerging pathogenesis and therapy concepts by Wang, Jin, Jiang, Mengmeng, Chen, Xin, Montaner, Luis J.

“…Clinical evidence indicates that the fatal outcome observed with severe acute respiratory syndrome‐coronavirus‐2 infection often results from alveolar injury…”
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Distinct Populations of Immune-Suppressive Macrophages Differentiate from Monocytic Myeloid-Derived Suppressor Cells in Cancer by Kwak, Taekyoung, Wang, Fang, Deng, Hui, Condamine, Thomas, Kumar, Vinit, Perego, Michela, Kossenkov, Andrew, Montaner, Luis J., Xu, Xiaowei, Xu, Wei, Zheng, Cathy, Schuchter, Lynn M., Amaravadi, Ravi K., Mitchell, Tara C., Karakousis, Giorgos C., Mulligan, Charles, Nam, Brian, Masters, Gregory, Hockstein, Neil, Bennett, Joseph, Nefedova, Yulia, Gabrilovich, Dmitry I.

“…Here, we report that functional heterogeneity of macrophages in cancer could be determined by the nature of their precursors: monocytes (Mons) and monocytic…”
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The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapy by McMyn, Natalie F, Varriale, Joseph, Fray, Emily J, Zitzmann, Carolin, MacLeod, Hannah, Lai, Jun, Singhal, Anushka, Moskovljevic, Milica, Garcia, Mauro A, Lopez, Brianna M, Hariharan, Vivek, Rhodehouse, Kyle, Lynn, Kenneth, Tebas, Pablo, Mounzer, Karam, Montaner, Luis J, Benko, Erika, Kovacs, Colin, Hoh, Rebecca, Simonetti, Francesco R, Laird, Gregory M, Deeks, Steven G, Ribeiro, Ruy M, Perelson, Alan S, Siliciano, Robert F, Siliciano, Janet M

“…HIV-1 persists in a latent reservoir in resting CD4+ T cells despite antiretroviral therapy (ART). The reservoir decays slowly over the first 7 years of ART…”
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The Natural Stilbenoid (–)-Hopeaphenol Inhibits Cellular Entry of SARS-CoV-2 USA-WA1/2020, B.1.1.7, and B.1.351 Variants by Tietjen, Ian, Cassel, Joel, Register, Emery T, Zhou, Xiang Yang, Messick, Troy E, Keeney, Frederick, Lu, Lily D, Beattie, Karren D, Rali, Topul, Tebas, Pablo, Ertl, Hildegund C. J, Salvino, Joseph M, Davis, Rohan A, Montaner, Luis J

“…Antivirals are urgently needed to combat the global SARS-CoV-2/COVID-19 pandemic, supplement existing vaccine efforts, and target emerging SARS-CoV-2 variants…”
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Non-invasive plasma glycomic and metabolic biomarkers of post-treatment control of HIV by Giron, Leila B., Palmer, Clovis S., Liu, Qin, Yin, Xiangfan, Papasavvas, Emmanouil, Sharaf, Radwa, Etemad, Behzad, Damra, Mohammad, Goldman, Aaron R., Tang, Hsin-Yao, Johnston, Rowena, Mounzer, Karam, Kostman, Jay R., Tebas, Pablo, Landay, Alan, Montaner, Luis J., Jacobson, Jeffrey M., Li, Jonathan Z., Abdel-Mohsen, Mohamed

“…Non-invasive biomarkers that predict HIV remission after antiretroviral therapy (ART) interruption are urgently needed. Such biomarkers can improve the safety…”
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Pegylated Interferon Alfa-2a Monotherapy Results in Suppression of HIV Type 1 Replication and Decreased Cell-Associated HIV DNA Integration by Azzoni, Livio, Foulkes, Andrea S., Papasavvas, Emmanouil, Mexas, Angela M., Lynn, Kenneth M., Mounzer, Karam, Tebas, Pablo, Jacobson, Jeffrey M., Frank, Ian, Busch, Michael P., Deeks, Steven G., Carrington, Mary, O'Doherty, Una, Kostman, Jay, Montaner, Luis J.

“…Background. Antiretroviral therapy (ART)-mediated immune reconstitution fails to restore the capacity of the immune system to spontaneously control human…”
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Galectin-9 Mediates HIV Transcription by Inducing TCR-Dependent ERK Signaling by Colomb, Florent, Giron, Leila B, Premeaux, Thomas A, Mitchell, Brooks I, Niki, Toshiro, Papasavvas, Emmanouil, Montaner, Luis J, Ndhlovu, Lishomwa C, Abdel-Mohsen, Mohamed

“…Endogenous plasma levels of the immunomodulatory carbohydrate-binding protein galectin-9 (Gal-9) are elevated during HIV infection and remain elevated after…”
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Phospholipid Metabolism Is Associated with Time to HIV Rebound upon Treatment Interruption by Giron, Leila B, Papasavvas, Emmanouil, Yin, Xiangfan, Goldman, Aaron R, Tang, Hsin-Yao, Palmer, Clovis S, Landay, Alan L, Li, Jonathan Z, Koethe, John R, Mounzer, Karam, Kostman, Jay R, Liu, Qin, Montaner, Luis J, Abdel-Mohsen, Mohamed

“…Lipids are biologically active molecules involved in a variety of cellular processes and immunological functions, including inflammation. It was recently shown…”
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Relationship Between Anemia and Systemic Inflammation in People Living With HIV and Tuberculosis: A Sub-Analysis of the CADIRIS Clinical Trial by Araújo-Pereira, Mariana, Barreto-Duarte, Beatriz, Arriaga, María B., Musselwhite, Laura W., Vinhaes, Caian L., Belaunzaran-Zamudio, Pablo F., Rupert, Adam, Montaner, Luis J., Lederman, Michael M., Sereti, Irini, Madero, Juan G. Sierra, Andrade, Bruno B.

“…People with HIV (PWH) are at increased risk of developing active tuberculosis (TB), and anemia is a common complication in both conditions. Anemia in TB…”
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HPLC-Based Purification and Isolation of Potent Anti-HIV and Latency Reversing Daphnane Diterpenes from the Medicinal Plant Gnidia sericocephala ( Thymelaeaceae ) by Tembeni, Babalwa, Sciorillo, Amanda, Invernizzi, Luke, Klimkait, Thomas, Urda, Lorena, Moyo, Phanankosi, Naidoo-Maharaj, Dashnie, Levitties, Nathan, Gyampoh, Kwasi, Zu, Guorui, Yuan, Zhe, Mounzer, Karam, Nkabinde, Siphathimandla, Nkabinde, Magugu, Gqaleni, Nceba, Tietjen, Ian, Montaner, Luis J, Maharaj, Vinesh

“…Despite the success of combination antiretroviral therapy (cART), HIV persists in low- and middle-income countries (LMIC) due to emerging drug resistance and…”
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A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function by Chitre, Avantika S, Kattah, Michael G, Rosli, Yenny Y, Pao, Montha, Deswal, Monika, Deeks, Steven G, Hunt, Peter W, Abdel-Mohsen, Mohamed, Montaner, Luis J, Kim, Charles C, Ma, Averil, Somsouk, Ma, McCune, Joseph M

“…ClinicalTrials.gov Clinical Trial NCT00594880…”
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A Trial of Intrapleural Adenoviral-mediated Interferon-α2b Gene Transfer for Malignant Pleural Mesothelioma by STERMAN, Daniel H, HAAS, Andrew, PAPASAWAS, Emmanouil, MONTANER, Luis J, HEITJAN, Daniel F, LITZKY, Leslie, FRIEDBERG, Joseph, CULLIGAN, Melissa, JUNE, Carl H, CARROLL, Richard G, ALBELDA, Steven M, MOON, Edmund, RECIO, Adriana, SCHWED, Daniel, VACHANI, Anil, KATZ, Sharyn I, GILLESPIE, Colin T, GUANJUN CHENG, JING SUN

“…New therapeutic strategies are needed for malignant pleural mesothelioma (MPM). We conducted a single-center, open-label, nonrandomized, pilot and feasibility…”
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Immune correlates of therapy outcomes in women with cervical cancer treated with chemoradiotherapy: A systematic review by Lakomy, David S., Wu, Juliana, Lombe, Dorothy, Papasavvas, Emmanouil, Msadabwe, Susan Citonje, Geng, Yimin, Montaner, Luis J., Chiao, Elizabeth, Lin, Lilie L.

“…Background Immune markers have been correlated with prognosis in a variety of solid tumors, including cervical cancer. Objective To review the literature on…”
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Identification of a 251 gene expression signature that can accurately detect M. tuberculosis in patients with and without HIV co-infection by Dawany, Noor, Showe, Louise C, Kossenkov, Andrew V, Chang, Celia, Ive, Prudence, Conradie, Francesca, Stevens, Wendy, Sanne, Ian, Azzoni, Livio, Montaner, Luis J

“…Co-infection with tuberculosis (TB) is the leading cause of death in HIV-infected individuals. However, diagnosis of TB, especially in the presence of an HIV…”
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Zinc reduces epithelial barrier compromise induced by human seminal plasma by Mullin, James M, Diguilio, Katherine M, Valenzano, Mary C, Deis, Rachael, Thomas, Sunil, Zurbach, E Peter, Abdulhaqq, Shaheed, Montaner, Luis J

“…Human semen has the potential to modulate the epithelial mucosal tissues it contacts, as seminal plasma (SP) is recognized to contain both pro- and…”
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Repeated semen exposure decreases cervicovaginal SIVmac251 infection in rhesus macaques by Abdulhaqq, Shaheed A., Martinez, Melween, Kang, Guobin, Rodriguez, Idia V., Nichols, Stephanie M., Beaumont, David, Joseph, Jocelin, Azzoni, Livio, Yin, Xiangfan, Wise, Megan, Weiner, David, Liu, Qin, Foulkes, Andrea, Münch, Jan, Kirchhoff, Frank, Coutifaris, Christos, Tomaras, Georgia D., Sariol, Carlos, Marx, Preston A., Li, Qingsheng, Kraiselburd, Edmundo N., Montaner, Luis J.

“…Semen is the vehicle for virion dissemination in the female reproductive tract (FRT) in male-to-female HIV transmission. Recent data suggests that higher…”
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Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro by Soilleux, Elizabeth J., Morris, Lesley S., Leslie, George, Chehimi, Jihed, Luo, Qi, Levroney, Ernest, Trowsdale, John, Montaner, Luis J., Doms, Robert W., Weissman, Drew, Coleman, Nicholas, Lee, Benhur

“…DC‐SIGN is a C‐type lectin, highly expressed on the surface ofimmature dendritic cells (DCs), that mediates efficient infection of Tcells in trans by its…”
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Early ART Results in Greater Immune Reconstitution Benefits in HIV-Infected Infants: Working with Data Missingness in a Longitudinal Dataset by Azzoni, Livio, Barbour, Russell, Papasavvas, Emmanouil, Glencross, Deborah K, Stevens, Wendy S, Cotton, Mark F, Violari, Avy, Montaner, Luis J

“…Early initiation of anti-retroviral treatment (ART) decreases mortality as compared to deferred treatment, but whether it preserves immune cells from early…”
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Microarray data on gene modulation by HIV-1 in immune cells: 2000–2006 by Giri, Malavika S., Nebozhyn, Michael, Showe, Louise, Montaner, Luis J.

“…Here, we review 34 HIV microarray studies in human immune cells over the period of 2000–March 2006 with emphasis on analytical approaches used and conceptual…”
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Natural Killer Cell Activation Distinguishes Mycobacterium tuberculosis–Mediated Immune Reconstitution Syndrome From Chronic HIV and HIV/MTB Coinfection by Conradie, Francesca, Foulkes, Andrea S, Ive, Prudence, Yin, Xiangfan, Roussos, Katerina, Glencross, Deborah K, Lawrie, Denise, Stevens, Wendy, Montaner, Luis J, Sanne, Ian, Azzoni, Livio

“…BACKGROUNDWith increased access to antiretroviral treatment (ART), immune reconstitution inflammatory syndrome (IRIS) in Mycobacterium tuberculosis…”
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