Search Results - "Montalbetti, Nicolas"

The Urothelium: Life in a Liquid Environment by Dalghi, Marianela G, Montalbetti, Nicolas, Carattino, Marcelo D, Apodaca, Gerard

“…The urothelium, which lines the renal pelvis, ureters, urinary bladder, and proximal urethra, forms a high-resistance but adaptable barrier that surveils its…”
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Reassessment of the Transport Mechanism of the Human Zinc Transporter SLC39A2 by Franz, Marie C, Pujol-Giménez, Jonai, Montalbetti, Nicolas, Fernandez-Tenorio, Miguel, DeGrado, Timothy R, Niggli, Ernst, Romero, Michael F, Hediger, Matthias A

“…The human zinc transporter SLC39A2, also known as ZIP2, was shown to mediate zinc transport that could be inhibited at pH <7.0 and stimulated by HCO3 –,…”
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Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception by Dalghi, Marianela G, Ruiz, Wily G, Clayton, Dennis R, Montalbetti, Nicolas, Daugherty, Stephanie L, Beckel, Jonathan M, Carattino, Marcelo D, Apodaca, Gerard

“…The mechanisms that link visceral mechanosensation to the perception of internal organ status (i.e., interoception) remain elusive. In response to bladder…”
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Urinary K+ promotes irritative voiding symptoms and pain in the face of urothelial barrier dysfunction by Montalbetti, Nicolas, Stocker, Sean D., Apodaca, Gerard, Bastacky, Sheldon I., Carattino, Marcelo D.

“…The internal surface of the bladder is lined by the urothelium, a stratified epithelium that forms an impermeable barrier to water and urine constituents…”
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Nutrient Transport in the Mammary Gland: Calcium, Trace Minerals and Water Soluble Vitamins by Montalbetti, Nicolas, Dalghi, Marianela G., Albrecht, Christiane, Hediger, Matthias A.

“…Milk nutrients are secreted by epithelial cells in the alveoli of the mammary gland by several complex and highly coordinated systems. Many of these nutrients…”
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Murine epithelial sodium (Na+) channel regulation by biliary factors by Wang, Xue-Ping, Im, Seohyun Janice, Balchak, Deidra M., Montalbetti, Nicolas, Carattino, Marcelo D., Ray, Evan C., Kashlan, Ossama B.

“…The epithelial sodium channel (ENaC) mediates Na+ transport in several epithelia, including the aldosterone-sensitive distal nephron, distal colon, and biliary…”
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Inhibition of the human epithelial calcium channel TRPV6 by 2-aminoethoxydiphenyl borate (2-APB) by Kovacs, Gergely, Montalbetti, Nicolas, Simonin, Alexandre, Danko, Tamas, Balazs, Bernadett, Zsembery, Akos, Hediger, Matthias A

“…Abstract TRPV6, a highly calcium-selective member of the transient receptor potential (TRP) channel superfamily, is a major pathway for calcium absorption in…”
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Human TRPV5 and TRPV6: Key players in cadmium and zinc toxicity by Kovacs, Gergely, Montalbetti, Nicolas, Franz, Marie-Christine, Graeter, Stefanie, Simonin, Alexandre, Hediger, Matthias A

“…Abstract TRPV5 and TRPV6 are two major calcium transport pathways in the human body maintaining calcium homeostasis. TRPV5 is mainly expressed in the distal…”
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Homeostasis of Extracellular ATP in Human Erythrocytes by Montalbetti, Nicolas, Leal Denis, Maria F., Pignataro, Omar P., Kobatake, Eiry, Lazarowski, Eduardo R., Schwarzbaum, Pablo J.

“…We explored the intra- and extracellular processes governing the kinetics of extracellular ATP (ATPe) in human erythrocytes stimulated with agents that…”
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Increased urothelial paracellular transport promotes cystitis by Montalbetti, Nicolas, Rued, Anna C, Clayton, Dennis R, Ruiz, Wily G, Bastacky, Sheldon I, Prakasam, H Sandeep, Eaton, Amity F, Kullmann, F Aura, Apodaca, Gerard, Carattino, Marcelo D

“…Changes in the urothelial barrier are observed in patients with cystitis, but whether this leads to inflammation or occurs in response to it is currently…”
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Expression and localization of the mechanosensitive/osmosensitive ion channel TMEM63B in the mouse urinary tract by Dalghi, Marianela G., DuRie, Ella, Ruiz, Wily G., Clayton, Dennis R., Montalbetti, Nicolas, Mutchler, Stephanie B., Satlin, Lisa M., Kleyman, Thomas R., Carattino, Marcelo D., Shi, Yun Stone, Apodaca, Gerard

“…The epithelial cells that line the kidneys and lower urinary tract are exposed to mechanical forces including shear stress and wall tension; however, the…”
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Vasopressin receptor-mediated functional signaling pathway in primary cilia of renal epithelial cells by Raychowdhury, Malay K, Ramos, Arnolt J, Zhang, Peng, McLaughin, Margaret, Dai, Xiao-Qing, Chen, Xing-Zhen, Montalbetti, Nicolás, Del Rocío Cantero, María, Ausiello, Dennis A, Cantiello, Horacio F

“…The primary cilium of renal epithelial cells is a nonmotile sensory organelle, implicated in mechanosensory transduction signals. Recent studies from our…”
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Urothelial Tight Junction Barrier Dysfunction Sensitizes Bladder Afferents by Montalbetti, Nicolas, Rued, Anna C, Taiclet, Stefanie N, Birder, Lori A, Kullmann, F Aura, Carattino, Marcelo D

“…Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic voiding disorder that presents with pain in the urinary bladder and surrounding pelvic…”
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Development and Validation of a Fast and Homogeneous Cell-Based Fluorescence Screening Assay for Divalent Metal Transporter 1 (DMT1/SLC11A2) Using the FLIPR Tetra by Montalbetti, Nicolas, Simonin, Alexandre, Dalghi, Marianela G, Kovacs, Gergely, Hediger, Matthias A

“…Divalent metal ion transporter 1 (DMT1) is a proton-coupled Fe(2+)transporter that is essential for iron uptake in enterocytes and for transferrin-associated…”
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Regulation of BK channel expression by Paraoxonase 3 by Shi, Shujie, Montalbetti, Nicolas, Kleyman, Thomas

“…Paraoxonase 3 (PON3) is a molecular chaperone that is primarily expressed in the aldosterone‐sensitive distal nephron (ASDN) where the fine tuning of Na+ and…”
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Chronic Pelvic Pain Develops in Sensory Neuron Conditional Asic3 Null Mice Subjected to Chemical Injury by Montalbetti, Nicolas, Dalghi, Marianela, Apodaca, Gerard, Carattino, Marcelo

“…Abstract only Sensitization of primary afferents is an important underlying mechanism for visceral hypersensitivity and pain. We investigated the contribution…”
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Acid-sensing ion channels modulate bladder nociception by Montalbetti, Nicolas, Carattino, Marcelo D

“…Sensitization of neuronal pathways and persistent afferent drive are major contributors to somatic and visceral pain. However, the underlying mechanisms that…”
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Frequency Spectrum of Transepithelial Potential Difference Reveals Transport-Related Oscillations by Montalbetti, Nicolás, Fischbarg, Jorge

“…How epithelia transport fluid is a fundamental issue that is unresolved. Explanations offered include molecular engines, local transcellular osmosis, local…”
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Polycystin-2 Cation Channel Function Is under the Control of Microtubular Structures in Primary Cilia of Renal Epithelial Cells by Li, Qiang, Montalbetti, Nicolás, Wu, Yuliang, Ramos, Arnolt, Raychowdhury, Malay K., Chen, Xing-Zhen, Cantiello, Horacio F.

“…Mutations in the gene encoding polycystin-2 (PC2) result in autosomal dominant polycystic kidney disease and defects in left-right asymmetry during…”
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Acid-sensing ion channels in sensory signaling by Carattino, Marcelo D, Montalbetti, Nicolas

“…Acid-sensing ion channels (ASICs) are cation-permeable channels that in the periphery are primarily expressed in sensory neurons that innervate tissues and…”
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