Search Results - "Montaño, Martha"
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Exosomal Micro-RNAs as Intercellular Communicators in Idiopathic Pulmonary Fibrosis
Published in International journal of molecular sciences (20-09-2022)“…Communication between neighboring or distant cells is made through a complex network that includes extracellular vesicles (EVs). Exosomes, which are a subgroup…”
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Mitochondrial Dysfunction and Alterations in Mitochondrial Permeability Transition Pore (mPTP) Contribute to Apoptosis Resistance in Idiopathic Pulmonary Fibrosis Fibroblasts
Published in International journal of molecular sciences (01-08-2021)“…Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by increased activation of fibroblasts/myofibroblasts. Previous reports have shown…”
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Cigarette Smoke Enhances the Expression of Profibrotic Molecules in Alveolar Epithelial Cells
Published in PloS one (02-03-2016)“…Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal disease of unknown etiology. A growing body of evidence indicates that it may result from an…”
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Fibroblasts From Idiopathic Pulmonary Fibrosis Induce Apoptosis and Reduce the Migration Capacity of T Lymphocytes
Published in Frontiers in immunology (10-02-2022)“…Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible lung disease of unknown etiology. Myofibroblasts are organized in peculiar subepithelial…”
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Dehydroepiandrosterone has strong antifibrotic effects and is decreased in idiopathic pulmonary fibrosis
Published in The European respiratory journal (01-11-2013)“…Idiopathic pulmonary fibrosis (IPF) is an ageing-related lung disorder characterised by expansion of the myofibroblast population and aberrant lung…”
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6
Mesenchymal stem cells attenuate the proinflammatory cytokine pattern in a guinea pig model of chronic cigarette smoke exposure
Published in Cytokine (Philadelphia, Pa.) (01-02-2023)“…•Chronic cigarette smoke exposure increased some serum and lung cytokines in guinea pigs.•A trend for an abnormal pattern of matrix metalloproteases and…”
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Women with COPD by biomass show different serum profile of adipokines, incretins, and peptide hormones than smokers
Published in Respiratory research (04-12-2018)“…The main causes of COPD are tobacco smoking (COPD-TS) and biomass smoke exposure (COPD-BS). COPD-TS is known to induce changes in adipokines, incretins, and…”
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miR-34a in serum is involved in mild-to-moderate COPD in women exposed to biomass smoke
Published in BMC pulmonary medicine (27-11-2019)“…Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar…”
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Mesenchymal-Epithelial Transition in Fibroblasts of Human Normal Lungs and Interstitial Lung Diseases
Published in Biomolecules (Basel, Switzerland) (04-03-2021)“… In passages above ten and growing very actively, we observed that some human lung fibroblasts cultured under standard conditions were transformed into a…”
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Short-Term Exposure to Wood Smoke Increases the Expression of Pro-Inflammatory Cytokines, Gelatinases, and TIMPs in Guinea Pigs
Published in Toxics (Basel) (20-09-2021)“…Exposure to air pollutants in wildfire smoke and indoor pollution causes lung diseases. Short-term exposure to wood smoke (WS) is partially known to alter the…”
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FEV1 inversely correlates with metalloproteinases 1, 7, 9 and CRP in COPD by biomass smoke exposure
Published in Respiratory research (30-06-2014)“…Matrix metalloproteinases (MMPs) and C-reactive protein (CRP) are involved in chronic obstructive pulmonary disease (COPD) pathogenesis. The aim of the present…”
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MMP-1 polymorphisms and the risk of idiopathic pulmonary fibrosis
Published in Human genetics (01-12-2008)“…Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive fibrotic lung disorder of unknown etiology and unclear pathogenesis. Matrix…”
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Women with COPD from biomass smoke have reduced serum levels of biomarkers of angiogenesis and cancer, with EGFR predominating, compared to women with COPD from smoking
Published in Chronic respiratory disease (2021)“…The main causes of COPD are smoking (COPD-TS) and exposure to biomass smoke (COPD-BS), considered as different phenotypes. The association of COPD-TS with lung…”
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14
Influence of proinflammatory cytokine gene polymorphisms on the risk of COPD and the levels of plasma protein
Published in Cytokine (Philadelphia, Pa.) (01-11-2018)“…•rs1818879/AA in IL6 is associated to an increased risk of COPD.•rs25882/T in CSF2 is associated to severe forms of the disease.•No difference between the…”
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Wood Smoke Extract Promotes Extracellular Matrix Remodeling in Normal Human Lung Fibroblasts
Published in International journal of toxicology (01-12-2021)“…Wood smoke (WS) contains many harmful compounds, including polycyclic aromatic hydrocarbons (PAHs). WS induces inflammation in the airways and lungs and can…”
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Deregulated MicroRNAs in Cancer-Associated Fibroblasts from Front Tumor Tissues of Lung Adenocarcinoma as Potential Predictors of Tumor Promotion
Published in The Tohoku Journal of Experimental Medicine (01-10-2018)“…Cancer-associated fibroblasts (CAFs) are the main component of the tumor stroma and promote tumor progression through several mechanisms. Recent evidence…”
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MMP2 Polymorphism Affects Plasma Matrix Metalloproteinase (MMP)-2 Levels, and Correlates with the Decline in Lung Function in Hypersensitivity Pneumonitis Positive to Autoantibodies Patients
Published in Biomolecules (Basel, Switzerland) (05-10-2019)“…Among hypersensitivity pneumonitis (HP) patients have been identified who develop autoantibodies with and without clinical manifestations of autoimmune…”
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Participation of the miR-22-HDAC4-DLCO Axis in Patients with COPD by Tobacco and Biomass
Published in Biomolecules (Basel, Switzerland) (06-12-2019)“…Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation and systemic inflammation. The main causes of COPD include interaction…”
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Fibroblasts from Idiopathic Pulmonary Fibrosis and Normal Lungs Differ in Growth Rate, Apoptosis, and Tissue Inhibitor of Metalloproteinases Expression
Published in American journal of respiratory cell and molecular biology (01-05-2001)“…Idiopathic pulmonary fibrosis (IPF) is a chronic lung disorder characterized by fibroblast proliferation and extracellular matrix accumulation. However,…”
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Genetic susceptibility to multicase hypersensitivity pneumonitis is associated with the TNF-238 GG genotype of the promoter region and HLA-DRB104 bearing HLA haplotypes
Published in Respiratory medicine (01-01-2014)“…Summary Hypersensitivity Pneumonitis (HP) is a lung inflammatory disorder caused by inhalation of organic particles by a susceptible host. Since only a small…”
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