Search Results - "Monsky, W L"

Effect of host microenvironment on the microcirculation of human colon adenocarcinoma by Fukumura, D, Yuan, F, Monsky, WL, Chen, Y, Jain, RK

“…It is generally accepted that the host microenvironment influences tumor biology. There are discrepancies in growth rate, metastatic potential, and efficacy of…”
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Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor by MONSKY, W. L, FUKUMURA, D, GOHONGI, T, ANCUKIEWCZ, M, WEICH, H. A, TORCHILIN, V. P, FAN YUAN, JAIN, R. K

“…The goal of this investigation was to measure changes in vascular permeability, pore cutoff size, and number of transvascular transport pathways as a function…”
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A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells by MONSKY, W. L, LIN, C.-Y, AOYAMA, A, KELLY, T, AKIYAMA, S. K, MUELLER, S. C, CHEN, W.-T

“…Seprase, a large, gelatin-degrading membrane-protease complex, is expressed at the invasive front of malignant melanoma cells on invadopodia, and its surface…”
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Protease production by cultured microglia: substrate gel analysis and immobilized matrix degradation by Colton, C A, Keri, J E, Chen, W T, Monsky, W L

“…The production of collagen-degrading proteases by cultured neonatal rat microglia was examined using an immobilized fibronectin-gelatin matrix coupled to a…”
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Regulation of Transport Pathways in Tumor Vessels: Role of Tumor Type and Microenvironment by Hobbs, Susan K., Monsky, Wayne L., Yuan, Fan, Roberts, W. Gregory, Griffith, Linda, Torchilin, Vladimir P., Jain, Rakesh K.

“…Novel anti-neoplastic agents such as gene targeting vectors and encapsulated carriers are quite large (approximately 100-300 nm in diameter). An understanding…”
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Comparison of Young Clinical Investigators’ Accuracy and Reproducibility When Measuring Pulmonary and Skin Surface Nodules Using a Circumferential Measurement Versus a Standard Caliper Measurement: American Association for Cancer Research/American Society of Clinical Oncology Clinical Trials Workshop by MONSKY, W. L, HEDDENS, D. K, CLARK, G. M, VON HOFF, D. D, COLTMAN, C. A, DORR, R. T, ALBERTS, D. S

“…The clinical investigator must understand that errors in measuring tumors can greatly affect such clinical-trial end points as tumor response. We performed a…”
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Using a Sonographic Simulator to Assess Residents Before Overnight Call by Monsky, Wayne L, Levine, Deborah, Mehta, Tejas S, Kane, Robert A, Ziv, Amitai, Kennedy, Bernadette, Nisenbaum, Harvey

“…The purpose of our study was to evaluate the effectiveness of a sonographic simulator in evaluating residents before their taking overnight call. A sonographic…”
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Binding and localization of M(r) 72,000 matrix metalloproteinase at cell surface invadopodia by Monsky, W L, Kelly, T, Lin, C Y, Yeh, Y, Stetler-Stevenson, W G, Mueller, S C, Chen, W T

“…Degradation (turnover) of collagenous matrix occurs on the surface of specialized membrane extensions termed "invadopodia," which are sites of cell invasion…”
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Mice lacking E-selectin show normal numbers of rolling leukocytes but reduced leukocyte stable arrest on cytokine-activated microvascular endothelium by Milstone, D S, Fukumura, D, Padgett, R C, O'Donnell, P E, Davis, V M, Benavidez, O J, Monsky, W L, Melder, R J, Jain, R K, Gimbrone, Jr, M A

“…Previous work indicated that E-selectin mediates transient interactions between leukocytes and cytokine-activated endothelium in vitro. Here we examine the…”
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Proteases of cell adhesion proteins in cancer by Monsky, W L, Chen, W T

“…Neoplastic cells elaborate a vast array of proteases that enable them to proteolytically digest underlying adhesion molecules. In doing this, the tumor cell…”
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Membrane proteases as potential diagnostic and therapeutic targets for breast malignancy by Chen, W T, Lee, C C, Goldstein, L, Bernier, S, Liu, C H, Lin, C Y, Yeh, Y, Monsky, W L, Kelly, T, Dai, M

“…Metastasizing cancer cells can invade the extracellular matrix using plasma membrane protrusions, termed invadopodia, that contact and dissolve the matrix…”
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Dual-balloon infusion microcatheter for selective drug-eluting bead transarterial chemoembolization: initial feasibility study by Monsky, Wayne L, Padia, Siddharth A, Hardy, Andrew Hal

“…We aimed to demonstrate feasibility of the use of a dual-balloon infusion microcatheter for segmental/subsegmental drug-eluting bead transarterial…”
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Binding and localization of Mr 72,000 matrix metalloproteinase at cell surface invadopodia by MONSKY, W. L, KELLY, T, CHEN-YONG LIN, YUNYUN YEH, STETLER-STEVENSON, G, MUELLER, S. C, WEN-TIEN CHEN

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Combination radiofrequency ablation with intratumoral liposomal doxorubicin: effect on drug accumulation and coagulation in multiple tissues and tumor types in animals by Ahmed, Muneeb, Liu, Zhengjun, Lukyanov, Anatoly N, Signoretti, Sabina, Horkan, Clare, Monsky, Wayne L, Torchilin, Vladimir P, Goldberg, S Nahum

“…To determine whether use of radiofrequency (RF) ablation combined with intravenously (IV) administered liposomal doxorubicin, as compared with use of RF…”
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Radiofrequency Ablation of Hepatic Tumors: Increased Tumor Destruction with Adjuvant Liposomal Doxorubicin Therapy by Goldberg, S. Nahum, Kamel, Ihab R, Kruskal, Jonathan B, Reynolds, Kevin, Monsky, Wayne L, Stuart, Keith E, Ahmed, Muneeb, Raptopoulos, Vassilos

“…The purpose of this study was to determine whether the administration of liposomal doxorubicin before radiofrequency ablation increases coagulation more than…”
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Role of Host Microenvironment in Angiogenesis and Microvascular Functions in Human Breast Cancer Xenografts: Mammary Fat Pad versus Cranial Tumors by MONSKY, Wayne L, MOUTA CARREIRA, Carla, TSUZUKI, Yoshikazu, GOHONGI, Takeshi, FUKUMURA, Dai, JAIN, Rakesh K

“…Purpose: The host microenvironment differs between primaryand metastatic sites, affecting gene expression and variousphysiological functions. Here we show the…”
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Percutaneous tumor ablation: increased necrosis with combined radio-frequency ablation and intravenous liposomal doxorubicin in a rat breast tumor model by Goldberg, S Nahum, Girnan, Geoffrey D, Lukyanov, Anatoly N, Ahmed, Muneeb, Monsky, Wayne L, Gazelle, G Scott, Huertas, Juan Carlos, Stuart, Keith E, Jacobs, Timothy, Torchillin, Vladimir P, Halpern, Elkan F, Kruskal, Jonathan B

“…To determine whether a combination of intravenous liposomal doxorubicin and radio-frequency (RF) ablation increases tumor destruction compared with RF alone in…”
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Radio-frequency ablation increases intratumoral liposomal doxorubicin accumulation in a rat breast tumor model by Monsky, Wayne L, Kruskal, Jonathan B, Lukyanov, Anatoly N, Girnun, Geoffrey D, Ahmed, Muneeb, Gazelle, G Scott, Huertas, Juan Carlos, Stuart, Keith E, Torchilin, Vladimir P, Goldberg, S Nahum

“…To determine whether intratumoral accumulation of liposomal doxorubicin or free unencapsulated doxorubicin is increased when combined with radio-frequency (RF)…”
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Reproducibility of linear tumor measurements using PACS: comparison of caliper method with edge-tracing method by Monsky, Wayne L, Raptopoulos, Vassilios, Keogan, Mary T, Doty, David, Kamel, Ihab, Yam, Chun Sam, Ransil, Bernard J

“…The aim of this study was to evaluate inter- and intra-observer reproducibility when making electronic caliper linear tumor measurements on picture archiving…”
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Membrane proteases as potential diagnostic and therapeutic targets for breast malignancy: The SPORE Program of the Vincent T. Lombardi Cancer Research Center by WEN-TIEN CHEN, CHONG-CHOU LEE, JING-YI ZHOU, MUELLER, S. C, GOLDSTEIN, L, BERNIER, S, LIU, C. H. L, CHEN-YONG LIN, YUNYUN YEH, MONSKY, W. L, KELLY, T, MAOZHENG DAI

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