Search Results - "Monsivais, Diana"

Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis by Monsivais, Diana, Nagashima, Takashi, Prunskaite-Hyyryläinen, Renata, Nozawa, Kaori, Shimada, Keisuke, Tang, Suni, Hamor, Clark, Agno, Julio E., Chen, Fengju, Masand, Ramya P., Young, Steven L., Creighton, Chad J., DeMayo, Francesco J., Ikawa, Masahito, Lee, Se-Jin, Matzuk, Martin M.

“…During early pregnancy in the mouse, nidatory estrogen (E2) stimulates endometrial receptivity by activating a network of signaling pathways that is not yet…”
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Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy by Liao, Zian, Tang, Suni, Nozawa, Kaori, Shimada, Keisuke, Ikawa, Masahito, Monsivais, Diana, Matzuk, Martin

“…Endometrial decidualization, a prerequisite for successful pregnancies, relies on transcriptional reprogramming driven by progesterone receptor (PR) and bone…”
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Activin-like kinase 5 (ALK5) inactivation in the mouse uterus results in metastatic endometrial carcinoma by Monsivais, Diana, Peng, Jia, Kang, Yibin, Matzuk, Martin M.

“…The endometrial lining of the uterine cavity is a highly dynamic tissue that is under the continuous control of the ovarian steroid hormones, estrogen and…”
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Progesterone Receptor Signaling in the Uterus Is Essential for Pregnancy Success by Cope, Dominique I, Monsivais, Diana

“…The uterus plays an essential role in the reproductive health of women and controls critical processes such as embryo implantation, placental development,…”
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Follistatin is critical for mouse uterine receptivity and decidualization by Fullerton, Paul T., Monsivais, Diana, Kommagani, Ramakrishna, Matzuk, Martin M.

“…Embryo implantation remains a significant challenge for assisted reproductive technology, with implantation failure occurring in ∼50% of in vitro fertilization…”
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Oocyte-specific Wee1-like protein kinase 2 is dispensable for fertility in mice by Nozawa, Kaori, Liao, Zian, Satouh, Yuhkoh, Geng, Ting, Ikawa, Masahito, Monsivais, Diana, Matzuk, Martin M

“…Wee1-like protein kinase 2 (WEE2) is an oocyte-specific protein tyrosine kinase involved in the regulation of oocyte meiotic arrest in humans. As such, it has…”
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Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers by Monsivais, Diana, Vasquez, Yasmin M., Chen, Fengju, Zhang, Yiqun, Chandrashekar, Darshan S., Faver, John C., Masand, Ramya P., Scheurer, Michael E., Varambally, Sooryanarayana, Matzuk, Martin M., Creighton, Chad J.

“…Proteomic signatures associated with clinical measures of more aggressive cancers could yield molecular clues as to disease drivers. Here, utilizing the…”
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Genome-wide DNA methylation analysis predicts an epigenetic switch for GATA factor expression in endometriosis by Dyson, Matthew T, Roqueiro, Damian, Monsivais, Diana, Ercan, C Mutlu, Pavone, Mary Ellen, Brooks, David C, Kakinuma, Toshiyuki, Ono, Masanori, Jafari, Nadereh, Dai, Yang, Bulun, Serdar E

“…Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-like cells that cause chronic pain and infertility. The disease is…”
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Uterine activin receptor-like kinase 5 is crucial for blastocyst implantation and placental development by Peng, Jia, Monsivais, Diana, You, Ran, Zhong, Hua, Pangas, Stephanie A., Matzuk, Martin M.

“…Members of the transforming growth factor β (TGF-β) superfamily are key regulators in most developmental and physiological processes. However, the in vivo…”
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Molecular biology of endometriosis: from aromatase to genomic abnormalities by Bulun, Serdar E, Monsivais, Diana, Kakinuma, Toshiyuki, Furukawa, Yuichi, Bernardi, Lia, Pavone, Mary Ellen, Dyson, Matthew

“…Endometriosis has been initially described as the presence of ectopic endometrial tissue on pelvic organs or in extrapelvic sites; and this has been used as…”
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Uterine ALK3 is essential during the window of implantation by Monsivais, Diana, Clementi, Caterina, Peng, Jia, Titus, Mary M., Barrish, James P., Creighton, Chad J., Lydon, John P., DeMayo, Francesco J., Matzuk, Martin M.

“…The window of implantation is defined by the inhibition of uterine epithelial proliferation, structural epithelial cell remodeling, and attenuated estrogen…”
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Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth by Ono, Masanori, Yin, Ping, Navarro, Antonia, Moravek, Molly B., Coon, John S., Druschitz, Stacy A., Serna, Vanida Ann, Qiang, Wenan, Brooks, David C., Malpani, Saurabh S., Ma, Jiajia, Ercan, Cihangir Mutlu, Mittal, Navdha, Monsivais, Diana, Dyson, Matthew T., Yemelyanov, Alex, Maruyama, Tetsuo, Chakravarti, Debabrata, Kim, J. Julie, Kurita, Takeshi, Gottardi, Cara J., Bulun, Serdar E.

“…Uterine leiomyomas are extremely common estrogen and progesterone-dependent tumors of the myometrium and cause irregular uterine bleeding, severe anemia, and…”
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Aberrant expression and localization of deoxyribonucleic acid methyltransferase 3B in endometriotic stromal cells by Dyson, Matthew T., Ph.D, Kakinuma, Toshiyuki, M.D, Pavone, Mary Ellen, M.D, Monsivais, Diana, Ph.D, Navarro, Antonia, Ph.D, Malpani, Saurabh S., M.S, Ono, Masanori, M.D, Bulun, Serdar E., M.D

“…Objective To define the expression and function of DNA methyltransferases (DNMTs) in response to decidualizing stimuli in endometriotic cells compared with…”
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Role of stem cells in human uterine leiomyoma growth by Ono, Masanori, Qiang, Wenan, Serna, Vanida Ann, Yin, Ping, Coon, 5th, John S, Navarro, Antonia, Monsivais, Diana, Kakinuma, Toshiyuki, Dyson, Matthew, Druschitz, Stacy, Unno, Kenji, Kurita, Takeshi, Bulun, Serdar E

“…Uterine leiomyoma is the most common benign tumor in reproductive-age women. Each leiomyoma is thought to be a benign monoclonal tumor arising from a single…”
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Estrogen receptor β regulates endometriotic cell survival through serum and glucocorticoid–regulated kinase activation by Monsivais, Diana, Ph.D, Dyson, Matthew T., Ph.D, Yin, Ping, Ph.D, Navarro, Antonia, Ph.D, Coon, John S., M.S, Pavone, Mary Ellen, M.D, Bulun, Serdar E., M.D

“…Objective To determine the expression and biological roles of serum and glucocorticoid–regulated kinase (SGK1) in tissues and cells from patients with…”
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Genome-wide DNA methylation indicates silencing of tumor suppressor genes in uterine leiomyoma by Navarro, Antonia, Yin, Ping, Monsivais, Diana, Lin, Simon M, Du, Pan, Wei, Jian-Jun, Bulun, Serdar E

“…Uterine leiomyomas, or fibroids, represent the most common benign tumor of the female reproductive tract. Fibroids become symptomatic in 30% of all women and…”
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Cell‐type specific analysis of physiological action of estrogen in mouse oviducts by McGlade, Emily A., Herrera, Gerardo G., Stephens, Kalli K., Olsen, Sierra L. W., Winuthayanon, Sarayut, Guner, Joie, Hewitt, Sylvia C., Korach, Kenneth S., DeMayo, Francesco J., Lydon, John P., Monsivais, Diana, Winuthayanon, Wipawee

“…One of the endogenous estrogens, 17β‐estradiol (E2) is a female steroid hormone secreted from the ovary. It is well established that E2 causes biochemical and…”
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A GREB1-steroid receptor feedforward mechanism governs differential GREB1 action in endometrial function and endometriosis by Chadchan, Sangappa B., Popli, Pooja, Liao, Zian, Andreas, Eryk, Dias, Michelle, Wang, Tianyuan, Gunderson, Stephanie J., Jimenez, Patricia T., Lanza, Denise G., Lanz, Rainer B., Foulds, Charles E., Monsivais, Diana, DeMayo, Francesco J., Yalamanchili, Hari Krishna, Jungheim, Emily S., Heaney, Jason D., Lydon, John P., Moley, Kelle H., O’Malley, Bert W., Kommagani, Ramakrishna

“…Cellular responses to the steroid hormones, estrogen (E2), and progesterone (P4) are governed by their cognate receptor’s transcriptional output. However, the…”
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Human Uterine Leiomyoma Stem/Progenitor Cells Expressing CD34 and CD49b Initiate Tumors In Vivo by Yin, Ping, Ono, Masanori, Moravek, Molly B, Coon, John S, Navarro, Antonia, Monsivais, Diana, Dyson, Matthew T, Druschitz, Stacy A, Malpani, Saurabh S, Serna, Vanida A, Qiang, Wenan, Chakravarti, Debabrata, Kim, J. Julie, Bulun, Serdar E

“…Context: Uterine leiomyoma is the most common benign tumor in reproductive-age women. Using a dye-exclusion technique, we previously identified a side…”
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5-Hydroxymethylcytosine Promotes Proliferation of Human Uterine Leiomyoma: A Biological Link to a New Epigenetic Modification in Benign Tumors by Navarro, Antonia, Yin, Ping, Ono, Masanori, Monsivais, Diana, Moravek, Molly B, Coon, John S, Dyson, Matthew T, Wei, Jian-Jun, Bulun, Serdar E

“…Context: Uterine leiomyoma, or fibroids, represent the most common benign tumors of the female reproductive tract. A newly discovered epigenetic modification,…”
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