Search Results - "Monshizadegan, H"

Binding and function of a potent new thromboxane receptor antagonist, BMS 180,291, in human platelets by Webb, M L, Liu, E C, Monshizadegan, H, Hedberg, A, Misra, R N, Goldenberg, H, Harris, D N

“…Binding and function of BMS 180,291 ([(+)1S-(1 alpha,2 alpha,3 alpha,4 alpha)]-2-[[3-[4-[(n-pentylamino)carbonyl]-2-oxazolyl]-7- oxabicyclo[2.2.1]…”
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Expression of endothelin receptor subtypes in rabbit saphenous vein by Webb, M L, Liu, E C, Monshizadegan, H, Chao, C C, Lynch, J, Fisher, S M, Rose, P M

“…Recent investigations have revealed the presence of vasoconstrictory endothelin (ET)-B receptors in several tissues, including the rabbit saphenous vein (RSV)…”
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Excessive ATP hydrolysis in ischemic myocardium by mitochondrial F1F0-ATPase: effect of selective pharmacological inhibition of mitochondrial ATPase hydrolase activity by Grover, Gary J, Atwal, Karnail S, Sleph, Paul G, Wang, Feng-Li, Monshizadegan, Hossain, Monticello, Thomas, Green, David W

“…Mitochondrial F(1)F(0)-ATPase normally synthesizes ATP in the heart, but under ischemic conditions this enzyme paradoxically causes ATP hydrolysis…”
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Dual Angiotensin II and Endothelin A Receptor Antagonists:  Synthesis of 2‘-Substituted N-3-Isoxazolyl Biphenylsulfonamides with Improved Potency and Pharmacokinetics by Murugesan, Natesan, Gu, Zhengxiang, Fadnis, Leena, Tellew, John E, Baska, Rose Ann F, Yang, Yifan, Beyer, Sophie M, Monshizadegan, Hossain, Dickinson, Kenneth E, Valentine, Maria T, Humphreys, W. Griffith, Lan, Shih-Jung, Ewing, William R, Carlson, Kenneth E, Kowala, Mark C, Zahler, Robert, Macor, John E

“…In a previous report we demonstrated that merging together key structural elements present in an AT1 receptor antagonist (1, irbesartan) with key structural…”
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Small Molecule Mitochondrial F1F0 ATPase Hydrolase Inhibitors as Cardioprotective Agents. Identification of 4-(N-Arylimidazole)-Substituted Benzopyran Derivatives as Selective Hydrolase Inhibitors by Atwal, Karnail S, Wang, Paulina, Rogers, W. Lynn, Sleph, Paul, Monshizadegan, Hossain, Ferrara, Francis N, Traeger, Sarah, Green, David W, Grover, Gary J

“…In this paper we show that 4-aryl-CH2-imidazole-substituted benzopyran compounds with 3S,4R-stereochemistry are cardioprotective by inhibiting the F1F0…”
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Benzodiazepine-based selective inhibitors of mitochondrial F1F0 ATP hydrolase by HAMANN, Lawrence G, DING, Charles Z, MILLER, Arthur V, MADSEN, Cort S, WANG, Paulina, STEIN, Philip D, PUDZIANOWSKI, Andrew T, GREEN, David W, MONSHIZADEGAN, Hossain, ATWAL, Karnail S

“…A series of benzodiazepine-based inhibitors of mitochondrial F(1)F(0) ATP hydrolase were prepared and evaluated for their ability to selectively inhibit the…”
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A switch in enantiomer preference between mitochondrial F1F0-ATPase chemotypes by BISAHA, Sharon N, MALLEY, Mary F, PUDZIANOWSKI, Andrew, MONSHIZADEGAN, Hossain, PAULINA WANG, MADSEN, Cort S, GOUGOUTAS, Jack Z, STEIN, Philip D

“…The preferred absolute configuration of two series of F(1)F(0)-ATP synthase inhibitors was determined. Although the configuration of the active enantiomer in…”
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Discovery of 4′-[(Imidazol-1-yl)methyl]biphenyl-2-sulfonamides as dual endothelin/Angiotensin II receptor antagonists by Tellew, John E, Baska, Rose Ann F, Beyer, Sophie M, Carlson, Kenneth E, Cornelius, Lyndon A, Fadnis, Leena, Gu, Zhengxiang, Kunst, Bridgette L, Kowala, Mark C, Monshizadegan, Hossain, Murugesan, Natesan, Ryan, Carol S, Valentine, Maria T, Yang, Yifan, Macor, John E

“…A series of 4′-[(imidazol-1-yl)methyl]biphenylsulfonamides has potent antagonist activity against both angiotensin II AT 1 and endothelin ET A receptors. Such…”
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The endothelin receptor antagonist, BQ-123, inhibits angiotensin II-induced contractions in rabbit aorta by Webb, M L, Dickinson, K E, Delaney, C L, Liu, E C, Serafino, R, Cohen, R B, Monshizadegan, H, Moreland, S

“…The purpose of this study was to examine the specificity of the cyclic pentapeptide ET(A) receptor antagonist BQ-123. BQ-123 competitively antagonized…”
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Substrate specificity of human plasma lecithin-cholesterol acyltransferase towards molecular species of phosphatidylcholine in native plasma by Subbaiah, P V, Monshizadegan, H

“…The specificity of human plasma lecithin-cholesterol acyltransferase for molecular species of phosphatidylcholine (PC) was studied by determining the molecular…”
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Molecular characterization of angiotensin II type II receptors in rat pheochromocytoma cells by Webb, M L, Liu, E C, Cohen, R B, Hedberg, A, Bogosian, E A, Monshizadegan, H, Molloy, C, Serafino, R, Moreland, S, Murphy, T J

“…The binding sites and biochemical effects of angiotensin (A) II were investigated in rat pheochromocytoma (PC12W) cells. Sarcosine1, [125I]-tyrosine4,…”
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Role of endothelin receptor subtype B (ET-B) in myocardial ischemia by Sargent, C A, Liu, E C, Chao, C C, Monshizadegan, H, Webb, M L, Grover, G J

“…Previous work indicated that endothelin (ET) may be involved in the pathogenesis of myocardial ischemia, although the relative importance of the ET receptor…”
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Characterization of binding of a specific antagonist, [3H]-SQ 29,548, to soluble thromboxane A2/prostaglandin H2 (TP) receptors in human platelet membranes by Monshizadegan, H, Hedberg, A, Webb, M L

“…Binding of [3H]-SQ 29,548 was characterized to soluble thromboxane A2/prostaglandin H2 (TP) receptors from human platelet membranes as a means of examining…”
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Interphenylene 7-oxabicyclo[2.2.1]heptane oxazoles. Highly potent, selective, and long-acting thromboxane A2 receptor antagonists by Misra, Raj N, Brown, Baerbel R, Sher, Philip M, Patel, Manorama M, Hall, Steven E, Han, Wen Ching, Barrish, Joel C, Kocy, Octavian, Harris, Don N

“…A series of interphenylene 7-oxabicyclo[2.2.1]heptane oxazoles (2) were prepared and evaluated for their thromboxane (TxA2) antagonistic activity in vitro and…”
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Binding and signal transduction of the cloned vascular angiotensin II (AT1a) receptor cDNA stably expressed in Chinese hamster ovary cells by Webb, M L, Monshizadegan, H, Dickinson, K E, Serafino, R, Moreland, S, Michel, I, Seiler, S M, Murphy, T J

“…The vascular angiotensin (A) II receptor cDNA (AT1a) was transfected into Chinese hamster ovary (CHO) cells to generate the stable cell line CHO-AT1a. This…”
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Binding of 125I-endothelin-1 and 125I-endothelin-3 in rabbit saphenous vein: evidence for an atypical ET binding component by Liu, E C, Monshizadegan, H, Chao, C C, Lynch, J, Fisher, S M, Rose, P M, Webb, M L

“…Recent investigations have confirmed the presence of vasoconstrictory endothelinB (ETB) receptors in several tissues, including the rabbit saphenous vein…”
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