Search Results - "Monleon, Inmaculada"

Blood amyloid beta levels in healthy, mild cognitive impairment and Alzheimer's disease individuals: replication of diastolic blood pressure correlations and analysis of critical covariates by Ruiz, Agustín, Pesini, Pedro, Espinosa, Ana, Pérez-Grijalba, Virginia, Valero, Sergi, Sotolongo-Grau, Oscar, Alegret, Montserrat, Monleón, Inmaculada, Lafuente, Asunción, Buendía, Mar, Ibarria, Marta, Ruiz, Susana, Hernández, Isabel, San José, Itziar, Tárraga, Lluís, Boada, Mercè, Sarasa, Manuel

“…Plasma amyloid beta (Aβ) levels are being investigated as potential biomarkers for Alzheimer's disease. In AB128 cross-sectional study, a number of medical…”
Get full text

Activated Human T Cells Release Bioactive Fas Ligand and APO2 Ligand in Microvesicles by Martinez-Lorenzo, Maria Jose, Anel, Alberto, Gamen, Susana, Monleon, Inmaculada, Lasierra, Pilar, Larrad, Luis, Pineiro, Andres, Alava, Maria A, Naval, Javier

“…Activation-induced cell death is a process by which overactivated T cells are eliminated, thus preventing potential autoimmune attacks. Two known mediators of…”
Get full text

Differential Secretion of Fas Ligand- or APO2 Ligand/TNF-Related Apoptosis-Inducing Ligand-Carrying Microvesicles During Activation-Induced Death of Human T Cells by Monleon, Inmaculada, Martinez-Lorenzo, Maria Jose, Monteagudo, Luis, Lasierra, Pilar, Taules, Marta, Iturralde, Maria, Pineiro, Andres, Larrad, Luis, Alava, Maria Angeles, Naval, Javier, Anel, Alberto

“…Preformed Fas ligand (FasL) and APO2 ligand (APO2L)/TNF-related apoptosis-inducing ligand (TRAIL) are stored in the cytoplasm of the human Jurkat T cell line…”
Get full text

Plasma Aβ42/40 ratio alone or combined with FDG-PET can accurately predict amyloid-PET positivity: a cross-sectional analysis from the AB255 Study by Pérez-Grijalba, Virginia, Arbizu, Javier, Romero, Judith, Prieto, Elena, Pesini, Pedro, Sarasa, Leticia, Guillen, Fernando, Monleón, Inmaculada, San-José, Itziar, Martínez-Lage, Pablo, Munuera, Josep, Hernández, Isabel, Buendía, Mar, Sotolongo-Grau, Oscar, Alegret, Montserrat, Ruiz, Agustín, Tárraga, Lluis, Boada, Mercè, Sarasa, Manuel

“…To facilitate population screening and clinical trials of disease-modifying therapies for Alzheimer's disease, supportive biomarker information is necessary…”
Get full text

Reliable Measurements of the β-Amyloid Pool in Blood Could Help in the Early Diagnosis of AD by Pesini, Pedro, Pérez-Grijalba, Virginia, Monleón, Inmaculada, Boada, Mercè, Tárraga, Lluís, Martínez-Lage, Pablo, San-José, Itziar, Sarasa, Manuel

“…The present study was aimed at assessing the capability of Aβ1-40 and Aβ1-42 levels in undiluted plasma (UP), diluted plasma (DP), and cell bound (CB) to…”
Get full text

Plasma β-amyloid peptides in canine aging and cognitive dysfunction as a model of Alzheimer's disease by González-Martínez, Ángela, Rosado, Belén, Pesini, Pedro, Suárez, María-Luisa, Santamarina, Germán, García–Belenguer, Sylvia, Villegas, Ainara, Monleón, Inmaculada, Sarasa, Manuel

“…Aging dogs naturally demonstrate cognitive impairment and neuropathology that model early Alzheimer's disease (AD). In particular, there is evidence that…”
Get full text

Cytotoxicity of quinone drugs on highly proliferative human leukemia T cells: Reactive oxygen species generation and inactive shortened SOD1 isoform implications by Aguiló, Juan Ignacio, Iturralde, María, Monleón, Inmaculada, Iñarrea, Pedro, Pardo, Julián, Martínez-Lorenzo, María José, Anel, Alberto, Alava, María Angeles

“…► Cytotoxicity of quinone drugs on hyperproliferative leukemia T cells is assessed. ► The mechanism of quinone drugs is mediated by Reactive Oxygen Species…”
Get full text

Safety, tolerability and immunogenicity of an active anti-Aβ40 vaccine (ABvac40) in patients with Alzheimer’s disease: a randomised, double-blind, placebo-controlled, phase I trial by Lacosta, Ana-María, Pascual-Lucas, María, Pesini, Pedro, Casabona, Diego, Pérez-Grijalba, Virginia, Marcos-Campos, Iván, Sarasa, Leticia, Canudas, Jesus, Badi, Hassnae, Monleón, Inmaculada, San-José, Itziar, Munuera, Josep, Rodríguez-Gómez, Octavio, Abdelnour, Carla, Lafuente, Asunción, Buendía, Mar, Boada, Mercè, Tárraga, Lluis, Ruiz, Agustín, Sarasa, Manuel

“…BACKGROUNDImmunotherapy targeting the amyloid-β (Aβ) peptide is a promising strategy for the treatment of Alzheimer's disease (AD); however, none of the active…”
Get full text

Several direct and calculated biomarkers from the amyloid-β pool in blood are associated with an increased likelihood of suffering from mild cognitive impairment by Pérez-Grijalba, Virginia, Pesini, Pedro, Monleón, Inmaculada, Boada, Mercè, Tárraga, Lluís, Ruiz-Laza, Agustín, Martínez-Lage, Pablo, San-José, Itziar, Sarasa, Manuel

“…Validation of cost-effective, non-invasive methods to identify early (pre-clinical) Alzheimer's disease (AD) is increasingly becoming a key research challenge…”
Get more information

A Role of the Mitochondrial Apoptosis-Inducing Factor in Granulysin-Induced Apoptosis by Pardo, Julian, Perez-Galan, Patricia, Gamen, Susana, Marzo, Isabel, Monleon, Inmaculada, Kaspar, Allan A, Susin, Santos A, Kroemer, Guido, Krensky, Alan M, Naval, Javier, Anel, Alberto

“…Granulysin is a cytolytic molecule released by CTL via granule-mediated exocytosis. In a previous study we showed that granulysin induced apoptosis using both…”
Get full text

The clinical significance of plasmatic amyloid A{beta}-40 peptide levels in Alzheimer's disease patients treated with galantamine by Modrego, Pedro J, Monleon, Inmaculada, Sarasa, Manuel

“…To date there are no conclusive reports on the usefulness of determining amyloid peptides in the serum of patients with Alzheimer's disease (AD). Only…”
Get full text

The Clinical Significance of Plasmatic Amyloid Aβ-40 Peptide Levels in Alzheimer's Disease Patients Treated With Galantamine by Modrego, Pedro J., Monleon, Inmaculada, Sarasa, Manuel

“…To date there are no conclusive reports on the usefulness of determining amyloid peptides in the serum of patients with Alzheimer's disease (AD). Only…”
Get full text

Saber tibia by Rubio Úbeda, Jesús, Jiménez Monleón, Inmaculada, Raya Álvarez, Enrique

Get full text

Safety, tolerability and immunogenicity of an active anti-Aβ 40 vaccine (ABvac40) in patients with Alzheimer's disease: a randomised, double-blind, placebo-controlled, phase I trial by Lacosta, Ana-María, Pascual-Lucas, María, Pesini, Pedro, Casabona, Diego, Pérez-Grijalba, Virginia, Marcos-Campos, Iván, Sarasa, Leticia, Canudas, Jesus, Badi, Hassnae, Monleón, Inmaculada, San-José, Itziar, Munuera, Josep, Rodríguez-Gómez, Octavio, Abdelnour, Carla, Lafuente, Asunción, Buendía, Mar, Boada, Mercè, Tárraga, Lluis, Ruiz, Agustín, Sarasa, Manuel

“…Immunotherapy targeting the amyloid-β (Aβ) peptide is a promising strategy for the treatment of Alzheimer's disease (AD); however, none of the active or…”
Get full text

Lack of Fas/CD95 surface expression in highly proliferative leukemic cell lines correlates with loss of CtBP/BARS and redirection of the protein toward giant lysosomal structures by MONLEON, Inmaculada, ITURRALDE, Maria, MARTINEZ-LORENZO, Maria José, MONTEAGUDO, Luis, LASIERRA, Pilar, LARRAD, Luis, PINEIRO, Andrés, NAVAL, Javier, ALAVA, Maria Angeles, ANEL, Alberto

“…Fas/CD95 is a type-I membrane glycoprotein, which inducesapoptotic cell death when ligated by its physiological ligand. We generated previously…”
Get full text

Plasma A[beta]42/40 ratio alone or combined with FDG-PET can accurately predict amyloid-PET positivity: a cross-sectional analysis from the AB255 Study by Pérez-Grijalba, Virginia, Arbizu, Javier, Romero, Judith, Prieto, Elena, Pesini, Pedro, Sarasa, Leticia, Guillen, Fernando, Monleón, Inmaculada, San-José, Itziar, Martínez-Lage, Pablo, Munuera, Josep, Hernández, Isabel, Buendía, Mar, Sotolongo-Grau, Oscar, Alegret, Montserrat, Ruiz, Agustín, Tárraga, Lluis, Boada, Mercè, Sarasa, Manuel, Goéi, Miguel, Pujadas, Francesc, Villarejo, Alberto, Frank, Ana, Peéa-Casanova, Jordi, Fernández, Manuel, Piéol, Gerard, Blesa, Rafael, Gil, Pedro, Pascual, Luis F, Aguilar, Miquel, Frisoni, Giovanni B, Matias-Guiu, Jorge, Andreasen, Niels, Antúnez, Carmen

“…Background To facilitate population screening and clinical trials of disease-modifying therapies for Alzheimer's disease, supportive biomarker information is…”
Get full text

Correction: Blood Amyloid Beta Levels in Healthy, Mild Cognitive Impairment and Alzheimer’s Disease Individuals: Replication of Diastolic Blood Pressure Correlations and Analysis of Critical Covariates by Ruiz, Agustín, Pesini, Pedro, Espinosa, Ana, Pérez-Grijalba, Virginia, Valero, Sergi, Sotolongo-Grau, Oscar, Alegret, Montserrat, Monleón, Inmaculada, Lafuente, Asunción, Buendía, Mar, Ibarria, Marta, Ruiz, Susana, Hernández, Isabel, San José, Itziar, Tárraga, Lluís, Boada, Mercè, Sarasa, Manuel

Get full text

Aβ blood levels and Alzheimer's disease by Pesini, Pedro, Pérez, Virginia, Monleón, Inmaculada, Boada, Mercè, Tarraga, Lluis, Sarasa, Manuel

Get full text

P2‐057: Aβ blood levels and Alzheimer's disease by Pesini, Pedro, Pérez, Virginia, Monleón, Inmaculada, Boada, Mercè, Tarraga, Lluis, Sarasa, Manuel

Get full text

O2‐03‐05: Beta‐amyloid‐17 is a major beta‐amyloid fragment isoform in cerebrospinal fluid and blood that shows diagnostic value by Pérez, Virginia, Sarasa, Leticia, Allue, Jose A., Casabona, Diego, Montanes, Maria, Insua, Daniel, Badi, Hassnae, Monleón, Inmaculada, Lacosta, Ana M., San Jose, Itziar, Tarraga, Lluis, Boada‐Rovira, Mercè, Pesini, Pedro, Sarasa, Manuel

Get full text