Search Results - "Monisha Dhiman"
-
1
Brain Exosomes: Friend or Foe in Alzheimer’s Disease?
Published in Molecular neurobiology (01-12-2021)“…Alzheimer’s disease (AD) is the most common neurodegenerative disease. It is known to be a multifactorial disease and several causes are associated with its…”
Get full text
Journal Article -
2
Inflammasome activation and regulation during Helicobacter pylori pathogenesis
Published in Microbial pathogenesis (01-12-2018)“…Helicobacter pylori is a leading cause of gastric cancer worldwide, its type four secretary toxin CagA is cited to be primarily responsible for it. Other…”
Get full text
Journal Article -
3
Mitigation of Gliadin-Induced Inflammation and Cellular Damage by Curcumin in Human Intestinal Cell Lines
Published in Inflammation (01-06-2021)“…Wheat is a major diet from many years; apart from its nutritious value, the wheat protein gliadin is responsible for many inflammatory diseases like celiac…”
Get full text
Journal Article -
4
APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions
Published in Experimental & molecular medicine (18-07-2014)“…Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional enzyme involved in the base excision repair (BER) pathway, which repairs oxidative base damage…”
Get full text
Journal Article -
5
A short review on cross-link between pyruvate kinase (PKM2) and Glioblastoma Multiforme
Published in Metabolic brain disease (01-06-2021)“…Pyruvate kinase (PK) catalyzes the last irreversible reaction of glycolysis pathway, generating pyruvate and ATP, from Phosphoenol Pyruvate (PEP) and ADP…”
Get full text
Journal Article -
6
P47phox-/- mice are compromised in expansion and activation of CD8+ T cells and susceptible to Trypanosoma cruzi infection
Published in PLoS pathogens (01-12-2014)“…Macrophage activation of NAD(P)H oxidase (NOX2) and reactive oxygen species (ROS) is suggested to kill Trypanosoma cruzi that causes Chagas disease. However,…”
Get full text
Journal Article -
7
Cardiac-oxidized antigens are targets of immune recognition by antibodies and potential molecular determinants in chagas disease pathogenesis
Published in PloS one (04-01-2012)“…Trypanosoma cruzi elicits reactive oxygen species (ROS) of inflammatory and mitochondrial origin in infected hosts. In this study, we examined ROS-induced…”
Get full text
Journal Article -
8
Phenyl-α-tert-butyl-nitrone and Benzonidazole Treatment Controlled the Mitochondrial Oxidative Stress and Evolution of Cardiomyopathy in Chronic Chagasic Rats
Published in Journal of the American College of Cardiology (01-06-2010)“…Objectives The purpose of this study was to determine the pathological importance of oxidative stress–induced injurious processes in chagasic heart…”
Get full text
Journal Article -
9
Innate immune responses and antioxidant/oxidant imbalance are major determinants of human Chagas disease
Published in PLoS neglected tropical diseases (01-08-2013)“…We investigated the pathological and diagnostic role of selected markers of inflammation, oxidant/antioxidant status, and cellular injury in human Chagas…”
Get full text
Journal Article -
10
Increased Myeloperoxidase Activity and Protein Nitration Are Indicators of Inflammation in Patients with Chagas' Disease
Published in Clinical and Vaccine Immunology (01-05-2009)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
11
Testing the efficacy of a multi-component DNA-prime/DNA-boost vaccine against Trypanosoma cruzi infection in dogs
Published in PLoS neglected tropical diseases (01-05-2011)“…Trypanosoma cruzi, the etiologic agent of Chagas Disease, is a major vector borne health problem in Latin America and an emerging infectious disease in the…”
Get full text
Journal Article -
12
Helicobacter pylori secretary Proteins-Induced oxidative stress and its role in NLRP3 inflammasome activation
Published in Cellular immunology (01-05-2024)“…Helicobacter pylori-associated stomach infection is a leading cause of gastric ulcer and related cancer. H. pylori modulates the functions of infiltrated…”
Get full text
Journal Article -
13
Helicobacter pylori secretory Proteins-Induced oxidative stress and its role in NLRP3 inflammasome activation
Published in Cellular immunology (01-05-2024)“…Helicobacter pylori-associated stomach infection is a leading cause of gastric ulcer and related cancer. H. pylori modulates the functions of infiltrated…”
Get full text
Journal Article -
14
Antigenicity and diagnostic potential of vaccine candidates in human Chagas disease
Published in PLoS neglected tropical diseases (01-01-2013)“…Chagas disease, caused by Trypanosoma cruzi, is endemic in Latin America and an emerging infectious disease in the US and Europe. We have shown TcG1, TcG2, and…”
Get full text
Journal Article -
15
Glycyrrhiza glabra (Licorice) root extract attenuates doxorubicin-induced cardiotoxicity via alleviating oxidative stress and stabilising the cardiac health in H9c2 cardiomyocytes
Published in Journal of ethnopharmacology (10-08-2020)“…Doxorubicin (DOX) is an effective anti-neoplastic drug, however; it has downside effects on cardiac health and other vital organs. The herbal remedies used in…”
Get full text
Journal Article -
16
Immunomodulatory and antibacterial effects of cystatin 9 against Francisella tularensis
Published in Molecular medicine (Cambridge, Mass.) (2013)“…Cystatin 9 (CST9) is a member of the type 2 cysteine protease inhibitor family, which has been shown to have immunomodulatory effects that restrain…”
Get full text
Journal Article -
17
NADPH oxidase inhibition ameliorates Trypanosoma cruzi-induced myocarditis during Chagas disease
Published in The Journal of pathology (01-12-2011)“…Trypanosoma cruzi, the aetiological agent of Chagas disease, invades nucleated mammalian cells including macrophages. In this study, we investigated the…”
Get full text
Journal Article -
18
Hydrogen peroxide-induced oxidative stress and its impact on innate immune responses in lung carcinoma A549 cells
Published in Molecular and cellular biochemistry (01-01-2019)“…The immune responses, involved in recognition of cancer-specific antigens, are of particular interest as this may provide major leads towards developing new…”
Get full text
Journal Article -
19
Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25–35)-induced oxidative stress and inflammatory responses
Published in Mitochondrion (01-11-2024)“…•Aβ leads to pronounced increase in oxidative stress in co-cultured neurons.•Differentiated macrophages express M1 phenotype upon Aβ stress.•These effects are…”
Get full text
Journal Article -
20
Role of immune system in tumor progression and carcinogenesis
Published in Journal of cellular biochemistry (01-07-2018)“…Tumor micro‐environment has potential to customize the behavior of the immune cell according to their need. In immune‐eliminating phase, immune cells eliminate…”
Get full text
Journal Article