Search Results - "Monia, B."

Common Premutations in the General Population by Hammer, Monia B, Singleton, Andrew B

Get more information

Mutations in GBA2 Cause Autosomal-Recessive Cerebellar Ataxia with Spasticity by Hammer, Monia B., Eleuch-Fayache, Ghada, Schottlaender, Lucia V., Nehdi, Houda, Gibbs, J. Raphael, Arepalli, Sampath K., Chong, Sean B., Hernandez, Dena G., Sailer, Anna, Liu, Guoxiang, Mistry, Pramod K., Cai, Huaibin, Shrader, Ginamarie, Sassi, Celeste, Bouhlal, Yosr, Houlden, Henry, Hentati, Fayçal, Amouri, Rim, Singleton, Andrew B.

“…Autosomal-recessive cerebellar ataxia (ARCA) comprises a large and heterogeneous group of neurodegenerative disorders with more than 20 different forms…”
Get full text

Targeted delivery of antisense oligonucleotides to pancreatic β-cells by Ämmälä, C, Drury, 3rd, W J, Knerr, L, Ahlstedt, I, Stillemark-Billton, P, Wennberg-Huldt, C, Andersson, E-M, Valeur, E, Jansson-Löfmark, R, Janzén, D, Sundström, L, Meuller, J, Claesson, J, Andersson, P, Johansson, C, Lee, R G, Prakash, T P, Seth, P P, Monia, B P, Andersson, S

“…Antisense oligonucleotide (ASO) silencing of the expression of disease-associated genes is an attractive novel therapeutic approach, but treatments are limited…”
Get full text

Clinical and genetic analyses of familial and sporadic frontotemporal dementia patients in Southern Italy by Capozzo, Rosa, Sassi, Celeste, Hammer, Monia B, Arcuti, Simona, Zecca, Chiara, Barulli, Maria R, Tortelli, Rosanna, Gibbs, J. Raphael, Crews, Cynthia, Seripa, Davide, Carnicella, Francesco, Dell'Aquila, Claudia, Rossi, Marco, Tamma, Filippo, Valluzzi, Francesco, Brancasi, Bruno, Panza, Francesco, Singleton, Andrew B, Logroscino, Giancarlo

“…Abstract Introduction We investigated the clinical differences between familial and sporadic frontotemporal dementia (FTD), screening for mutations in known…”
Get full text

Coagulation factor XI as a novel target for antithrombotic treatment by LÖWENBERG, E. C., MEIJERS, J. C. M., MONIA, B. P., LEVI, M.

“…Coagulation factor (F)XI was first described as a member of the contact pathway of coagulation. However, the ‘classic’ theory of the extrinsic and intrinsic…”
Get full text

ASO-mediated Dnm2 knockdown prevents and reverts myotubular myopathy in mice by Tasfaout, H, Buono, S, Guo, S, Kretz, C, Monia, B, Cowling, B, Laporte, J

Get full text

SLC25A46 Mutations Associated with Autosomal Recessive Cerebellar Ataxia in North African Families by Hammer, Monia B, Ding, Jinhui, Mochel, Fanny, Eleuch-Fayache, Ghada, Charles, Perrine, Coutelier, Marie, Gibbs, J Raphael, Arepalli, Sampath K, Chong, Sean B, Hernandez, Dena G, Majounie, Elisa, Clipman, Steven, Bouhlal, Yosr, Nehdi, Houda, Brice, Alexis, Hentati, Faycal, Stevanin, Giovanni, Amouri, Rim, Durr, Alexandra, Singleton, Andrew B

“…Autosomal recessive cerebellar ataxias (ARCA) are a complex group of neurodegenerative disorders with high clinical and genetic heterogeneity. In most cases,…”
Get more information

WS01.1 Identification of a human antisense inhibitor against ENaC for the treatment of cystic fibrosis by Guo, S, Crosby, J, Zhao, C, Bai, D, Mccaleb, M, Rotin, D, Monia, B

Get full text

Knockdown of the gene encoding Drosophila tribbles homologue 3 (Trib3) improves insulin sensitivity through peroxisome proliferator-activated receptor-γ (PPAR-γ) activation in a rat model of insulin resistance by Weismann, D, Erion, D. M, Ignatova-Todorava, I, Nagai, Y, Stark, R, Hsiao, J. J, Flannery, C, Birkenfeld, A. L, May, T, Kahn, M, Zhang, D, Yu, X. X, Murray, S. F, Bhanot, S, Monia, B. P, Cline, G. W, Shulman, G. I, Samuel, V. T

“…Aims/hypothesis Insulin action is purportedly modulated by Drosophila tribbles homologue 3 (TRIB3), which in vitro prevents thymoma viral proto-oncogene (AKT)…”
Get full text

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients by Nagata, Yoichi, Lan, Keng-Hsueh, Zhou, Xiaoyan, Tan, Ming, Esteva, Francisco J., Sahin, Aysegul A., Klos, Kristine S., Li, Ping, Monia, Brett P., Nguyen, Nina T., Hortobagyi, Gabriel N., Hung, Mien-Chie, Yu, Dihua

“…The ErbB2-targeting antibody, trastuzumab (Herceptin), has remarkable therapeutic efficacy in certain patients with ErbB2-overexpressing tumors. The overall…”
Get full text

Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases by MARGHERI, F, D'ALESSIO, S, RUCCI, N, BOLOGNA, M, TETI, A, MONIA, B, FIBBI, G, DEL ROSSO, M, SERRATI, S, PUCCI, M, ANNUNZIATO, F, COSMI, L, LIOTTA, F, ANGELI, R, ANGELUCCI, A, GRAVINA, G. L

“…An important factor implicated in tumor cell predisposition for invasion and metastasis is the malignancy-related upregulation of urokinase plasminogen…”
Get full text

Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression by MONIA, B. P, LESNIK, E. A, GONZALEZ, C, LIMA, W. F, MCGEE, D, GUINOSSO, C. J, KAWASAKI, A. M, COOK, P. D, FREIER, S. M

“…We have used a previously described 17-mer phosphorothioate (Monia, B.P., Johnston, J.F., Ecker, D. J., Zounes, M.A., Lima, W.F., and Freier, S.M. (1992) J…”
Get full text

Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer by MCPHILLIPS, F, MULLEN, P, MONIA, B. P, RITCHIE, A. A, DORR, F. A, SMYTH, J. F, LANGDON, S. P

“…c-Raf is an essential component of the extracellular related kinase (ERK) signal transduction pathway. Immunohistochemical staining indicated that c-Raf was…”
Get full text

Bcl-xL antisense oligonucleotides radiosensitise colon cancer cells by WACHECK, V, SELZER, E, GÜNSBERG, P, LUCAS, T, MEYER, H, THALLINGER, C, MONIA, B. P, JANSEN, B

“…Advanced colon cancer is a malignancy with poor response to various treatment modalities including ionising radiation (IR) and chemotherapy. Both IR and…”
Get full text

Kinetic characteristics of Escherichia coli RNase H1: cleavage of various antisense oligonucleotide-RNA duplexes by Crooke, S T, Lemonidis, K M, Neilson, L, Griffey, R, Lesnik, E A, Monia, B P

“…1. The effects of variations in substrates on the kinetic properties of Escherichia coli RNase H were studied using antisense oligonucleotides of various types…”
Get full text

Polyethyleneimine grafted with pluronic P85 enhances Ku86 antisense delivery and the ionizing radiation treatment efficacy in vivo by BELENKOV, A. I, ALAKHOV, V. Y, KABANOV, A. V, VINOGRADOV, S. V, PANASCI, L. C, MONIA, B. P, CHOW, T. Y. K

“…In an effort to improve the efficacy of antisense delivery, we evaluated polyethyleneimine (PEI, 2 kDa) alone or grafted with nonionic amphiphilic block…”
Get full text

Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway by Schulte, Theodor W., Blagosklonny, Mikhail V., Romanova, Larissa, Mushinski, J. Frederic, Monia, Brett P., Johnston, Joseph F., Nguyen, Phuongmai, Trepel, Jane, Neckers, Leonard M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

The role of transforming growth factor-β in carcinogenesis by Gleave, M, Monia, B. P

Get full text

Inhibition of spinal cytosolic phospholipase A(2) expression by an antisense oligonucleotide attenuates tissue injury-induced hyperalgesia by Kim, D H, Fitzsimmons, B, Hefferan, M P, Svensson, C I, Wancewicz, E, Monia, B P, Hung, G, Butler, M, Marsala, M, Hua, X-Y, Yaksh, T L

“…Activation of the spinal phospholipase A(2) (PLA(2)) -cyclooxygenase (COX) -prostaglandin signaling pathway is widely implicated in nociceptive processing…”
Get full text

Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant by Finley, D, Sadis, S, Monia, B P, Boucher, P, Ecker, D J, Crooke, S T, Chau, V

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text