Search Results - "Moni, Lisa"
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Synthesis of spiroindolenines through a one-pot multistep process mediated by visible light
Published in Beilstein journal of organic chemistry (29-10-2024)“…Spiro-heterocyclic indolenines are privileged scaffolds widely present in numerous indole alkaloids. Here, we develop a novel approach for the one-pot…”
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Ugi and Passerini Reactions of Biocatalytically Derived Chiral Aldehydes: Application to the Synthesis of Bicyclic Pyrrolidines and of Antiviral Agent Telaprevir
Published in Journal of organic chemistry (03-04-2015)“…Lipase mediated desymmetrization of a meso-diol (1,2-cyclopentanedimethanol) allows the synthesis of both enantiomers of some chiral aldehydes, whose behavior…”
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Total Synthesis of 4- epi -Bengamide E
Published in Molecules (Basel, Switzerland) (10-04-2024)“…Bengamide E is a bioactive natural product that was isolated from Jaspidae sponges by Crews and co-workers in 1989. It displays a wide range of biological…”
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4
Bicyclic Heterocycles from Levulinic Acid through a Fast and Operationally Simple Diversity‐Oriented Multicomponent Approach
Published in European journal of organic chemistry (24-10-2018)“…Levulinic acid, which is one of the most important renewable building blocks derived from lignocellulosic biomass, has been converted in a diversity‐oriented…”
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5
Synthesis, Photoisomerization, Antioxidant Activity, and Lipid-Lowering Effect of Ferulic Acid and Feruloyl Amides
Published in Molecules (Basel, Switzerland) (28-12-2020)“…The Ugi four-component reaction employing naturally occurred ferulic acid (FA) is proposed as a convenient method to synthesize feruloyl tertiary amides…”
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Multi-Gram Synthesis of Enantiopure 1,5-Disubstituted Tetrazoles Via Ugi-Azide 3-Component Reaction
Published in Molecules (Basel, Switzerland) (25-10-2018)“…Tetrazoles have been widely studied for their biological properties. An efficient route for large-scale synthesis of 1,5-disubstituted tetrazoles (1,5-DTs) is…”
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Synthesis of Polyoxygenated Heterocycles by Diastereoselective Functionalization of a Bio-Based Chiral Aldehyde Exploiting the Passerini Reaction
Published in Molecules (Basel, Switzerland) (15-07-2020)“…A chiral bio-based building block, prepared by the lipase-mediated desymmetrization of an erythritol derivative, was further functionalized and then submitted…”
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Multicomponent Synthesis of Polyphenols and their in vitro Evaluation as Potential β-Amyloid Aggregation Inhibitors
Published in Molecules (Basel, Switzerland) (19-07-2019)“…While plant polyphenols possess a variety of biological properties, exploration of chemical diversity around them is still problematic. Here, an example of…”
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Passerini Reactions on Biocatalytically Derived Chiral Azetidines
Published in Molecules (Basel, Switzerland) (30-08-2016)“…The purpose of this study was to explore a series of Passerini reactions on a biocatalytically derived enantiopure azetidine-2-carboxyaldehyde in order to…”
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Editorial: Diversity Oriented Synthesis
Published in Frontiers in chemistry (24-01-2019)Get full text
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Synthesis of sialoclusters appended to calix[4]arene platforms via multiple azide-alkyne cycloaddition. New inhibitors of hemagglutination and cytopathic effect mediated by BK and influenza A viruses
Published in Organic & biomolecular chemistry (01-01-2008)“…Tetra- and octavalent sialoside clusters were prepared in good yields exploiting for the first time the multiple copper-catalyzed cycloaddition of a propargyl…”
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Photocatalyzed synthesis of isochromanones and isobenzofuranones under batch and flow conditions
Published in Beilstein journal of organic chemistry (25-07-2017)“…Photocatalyzed reactions of 2-(alkoxycarbonyl)benzenediazonium tetrafluoroborates with various alkenes afforded isochromanones in good yields, according to a…”
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Diastereoselective Ugi reaction of chiral 1,3-aminoalcohols derived from an organocatalytic Mannich reaction
Published in Beilstein journal of organic chemistry (26-01-2016)“…Enantiomerically pure β-aminoalcohols, produced through an organocatalytic Mannich reaction, were subjected to an Ugi multicomponent reaction under classical…”
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Diversity-oriented synthesis of dihydrobenzoxazepinones by coupling the Ugi multicomponent reaction with a Mitsunobu cyclization
Published in Beilstein journal of organic chemistry (17-01-2014)“…An operationally simple protocol for the synthesis of 2,3-dihydrobenzo[f][1,4]oxazepin-3-ones, based on an Ugi reaction of an ortho-(benzyloxy)benzylamine,…”
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Exploitation of the Ugi 5-Center-4-Component Reaction (U-5C-4CR) for the Generation of Diverse Libraries of Polycyclic (Spiro)Compounds
Published in Frontiers in chemistry (2018)“…An Ugi multicomponent reaction with chiral cyclic amino acids, benzyl isocyanide and cyclic ketones (or acetone) has been exploited as key step for the…”
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Synthesis of rapamycin glycoconjugates via a CuAAC-based approach
Published in Tetrahedron letters (01-12-2013)“…The conversion of the C40 secondary hydroxyl group of rapamycin into the azido group was followed by copper catalyzed cycloaddition of the resulting…”
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Regioselective Photooxidation of Citronellol: A Way to Monomers for Functionalized Bio-Polyesters
Published in Frontiers in chemistry (13-02-2020)“…Dye-sensitized photooxygenation reaction of bio-based double bond-containing substrates is proposed as sustainable functionalization of terpenes and terpenoids…”
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Corrigendum: Exploitation of the Ugi 5-Center-4-Component Reaction (U-5C-4CR) for the Generation of Diverse Libraries of Polycyclic (Spiro)Compounds
Published in Frontiers in chemistry (19-10-2018)“…[This corrects the article DOI: 10.3389/fchem.2018.00369.]…”
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The 100 facets of the Passerini reaction
Published in Chemical science (Cambridge) (08-12-2021)“…This perspective aims at celebrating the 100th anniversary of the discovery of the Passerini three component reaction. After being nearly neglected for many…”
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Diastereoselectivity in Passerini Reactions of Chiral Aldehydes and in Ugi Reactions of Chiral Cyclic Imines
Published in European journal of organic chemistry (07-07-2020)“…Diastereoselectivity in Passerini and Ugi reactions of chiral aldehydes/imines remains challenging. Moreover, the Ugi reaction of chiral acyclic imines is…”
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