Search Results - "Mongkolsapaya, Juthathip"

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19 by Peng, Yanchun, Mentzer, Alexander J., Liu, Guihai, Yao, Xuan, Yin, Zixi, Dong, Danning, Dejnirattisai, Wanwisa, Rostron, Timothy, Supasa, Piyada, Liu, Chang, López-Camacho, César, Slon-Campos, Jose, Zhao, Yuguang, Stuart, David I., Paesen, Guido C., Grimes, Jonathan M., Antson, Alfred A., Bayfield, Oliver W., Hawkins, Dorothy E. D. P., Ker, De-Sheng, Wang, Beibei, Turtle, Lance, Subramaniam, Krishanthi, Thomson, Paul, Zhang, Ping, Dold, Christina, Ratcliff, Jeremy, Simmonds, Peter, de Silva, Thushan, Sopp, Paul, Wellington, Dannielle, Rajapaksa, Ushani, Chen, Yi-Ling, Salio, Mariolina, Napolitani, Giorgio, Paes, Wayne, Borrow, Persephone, Kessler, Benedikt M., Fry, Jeremy W., Schwabe, Nikolai F., Semple, Malcolm G., Baillie, J. Kenneth, Moore, Shona C., Openshaw, Peter J. M., Ansari, M. Azim, Dunachie, Susanna, Barnes, Eleanor, Frater, John, Kerr, Georgina, Goulder, Philip, Lockett, Teresa, Levin, Robert, Zhang, Yonghong, Jing, Ronghua, Ho, Ling-Pei, Cornall, Richard J., Conlon, Christopher P., Klenerman, Paul, Screaton, Gavin R., Mongkolsapaya, Juthathip, McMichael, Andrew, Knight, Julian C., Ogg, Graham, Dong, Tao

“…The development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines and therapeutics will depend on understanding viral immunity. We…”
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A protective Zika virus E-dimer-based subunit vaccine engineered to abrogate antibody-dependent enhancement of dengue infection by Slon-Campos, Jose Luis, Dejnirattisai, Wanwisa, Jagger, Brett W., López-Camacho, César, Wongwiwat, Wiyada, Durnell, Lorellin A., Winkler, Emma S., Chen, Rita E., Reyes-Sandoval, Arturo, Rey, Felix A., Diamond, Michael S., Mongkolsapaya, Juthathip, Screaton, Gavin R.

“…Infections with dengue virus (DENV) and Zika virus (ZIKV) can induce cross-reactive antibody responses. Two immunodominant epitopes—one to precursor membrane…”
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Structural basis of potent Zika–dengue virus antibody cross-neutralization by Barba-Spaeth, Giovanna, Dejnirattisai, Wanwisa, Rouvinski, Alexander, Vaney, Marie-Christine, Medits, Iris, Sharma, Arvind, Simon-Lorière, Etienne, Sakuntabhai, Anavaj, Cao-Lormeau, Van-Mai, Haouz, Ahmed, England, Patrick, Stiasny, Karin, Mongkolsapaya, Juthathip, Heinz, Franz X., Screaton, Gavin R., Rey, Félix A.

“…Zika virus is a member of the Flavivirus genus that had not been associated with severe disease in humans until the recent outbreaks, when it was linked to…”
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Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike by Huo, Jiandong, Zhao, Yuguang, Ren, Jingshan, Zhou, Daming, Duyvesteyn, Helen M.E., Ginn, Helen M., Carrique, Loic, Malinauskas, Tomas, Ruza, Reinis R., Shah, Pranav N.M., Tan, Tiong Kit, Rijal, Pramila, Coombes, Naomi, Bewley, Kevin R., Tree, Julia A., Radecke, Julika, Paterson, Neil G., Supasa, Piyada, Mongkolsapaya, Juthathip, Screaton, Gavin R., Carroll, Miles, Townsend, Alain, Fry, Elizabeth E., Owens, Raymond J., Stuart, David I.

“…There are as yet no licensed therapeutics for the COVID-19 pandemic. The causal coronavirus (SARS-CoV-2) binds host cells via a trimeric spike whose receptor…”
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Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins by Renner, Max, Dejnirattisai, Wanwisa, Carrique, Loïc, Martin, Itziar Serna, Karia, Dimple, Ilca, Serban L., Ho, Shu F., Kotecha, Abhay, Keown, Jeremy R., Mongkolsapaya, Juthathip, Screaton, Gavin R., Grimes, Jonathan M.

“…Flaviviruses such as Dengue (DENV) or Zika virus (ZIKV) assemble into an immature form within the endoplasmatic reticulum (ER), and are then processed by furin…”
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An immunodominant NP105–113-B07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease by Peng, Yanchun, Felce, Suet Ling, Dong, Danning, Penkava, Frank, Mentzer, Alexander J., Yao, Xuan, Liu, Guihai, Yin, Zixi, Chen, Ji-Li, Lu, Yongxu, Wellington, Dannielle, Wing, Peter A. C., Dominey-Foy, Delaney C. C., Jin, Chen, Wang, Wenbo, Hamid, Megat Abd, Fernandes, Ricardo A., Wang, Beibei, Fries, Anastasia, Zhuang, Xiaodong, Ashley, Neil, Rostron, Timothy, Waugh, Craig, Sopp, Paul, Hublitz, Philip, Beveridge, Ryan, Tan, Tiong Kit, Dold, Christina, Kwok, Andrew J., Rich-Griffin, Charlotte, Dejnirattisa, Wanwisa, Liu, Chang, Kurupati, Prathiba, Nassiri, Isar, Watson, Robert A., Tong, Orion, Taylor, Chelsea A., Kumar Sharma, Piyush, Sun, Bo, Curion, Fabiola, Revale, Santiago, Garner, Lucy C., Jansen, Kathrin, Ferreira, Ricardo C., Attar, Moustafa, Fry, Jeremy W., Russell, Rebecca A., Stauss, Hans J., James, William, Townsend, Alain, Ho, Ling-Pei, Klenerman, Paul, Mongkolsapaya, Juthathip, Screaton, Gavin R., Dendrou, Calliope, Sansom, Stephen N., Bashford-Rogers, Rachael, Chain, Benny, Smith, Geoffrey L., McKeating, Jane A., Fairfax, Benjamin P., Bowness, Paul, McMichael, Andrew J., Ogg, Graham, Knight, Julian C., Dong, Tao

“…NP 105–113 -B*07:02-specific CD8 + T cell responses are considered among the most dominant in SARS-CoV-2-infected individuals. We found strong association of…”
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Cross-Reacting Antibodies Enhance Dengue Virus Infection in Humans by Dejnirattisai, Wanwisa, Jumnainsong, Amonrat, Onsirisakul, Naruthai, Fitton, Patricia, Vasanawathana, Sirijitt, Limpitikul, Wannee, Puttikhunt, Chunya, Edwards, Carolyn, Duangchinda, Thaneeya, Supasa, Sunpetchuda, Chawansuntati, Kriangkrai, Malasit, Prida, Mongkolsapaya, Juthathip, Screaton, Gavin

“…Dengue virus co-circulates as four serotypes, and sequential infections with more than one serotype are common. One hypothesis for the increased severity seen…”
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Anti-spike antibody response to natural SARS-CoV-2 infection in the general population by Wei, Jia, Matthews, Philippa C., Stoesser, Nicole, Maddox, Thomas, Lorenzi, Luke, Studley, Ruth, Bell, John I., Newton, John N., Farrar, Jeremy, Diamond, Ian, Rourke, Emma, Howarth, Alison, Marsden, Brian D., Hoosdally, Sarah, Jones, E. Yvonne, Stuart, David I., Crook, Derrick W., Peto, Tim E. A., Pouwels, Koen B., Walker, A. Sarah, Eyre, David W.

“…Understanding the trajectory, duration, and determinants of antibody responses after SARS-CoV-2 infection can inform subsequent protection and risk of…”
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Longitudinal Analysis of Antibody Cross-neutralization Following Zika Virus and Dengue Virus Infection in Asia and the Americas by Montoya, Magelda, Collins, Matthew, Dejnirattisai, Wanwisa, Katzelnick, Leah C, Puerta-Guardo, Henry, Jadi, Ramesh, Schildhauer, Samuel, Supasa, Piyada, Vasanawathana, Sirijitt, Malasit, Prida, Mongkolsapaya, Juthathip, de Silva, Aruna D, Tissera, Hasitha, Balmaseda, Angel, Screaton, Gavin, de Silva, Aravinda M, Harris, Eva

“…The 4 dengue virus serotypes (DENV1-4) and Zika virus (ZIKV) are related mosquito-borne flaviviruses of major importance globally. While monoclonal antibodies…”
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Recognition determinants of broadly neutralizing human antibodies against dengue viruses by Rouvinski, Alexander, Guardado-Calvo, Pablo, Barba-Spaeth, Giovanna, Duquerroy, Stéphane, Vaney, Marie-Christine, Kikuti, Carlos M., Navarro Sanchez, M. Erika, Dejnirattisai, Wanwisa, Wongwiwat, Wiyada, Haouz, Ahmed, Girard-Blanc, Christine, Petres, Stéphane, Shepard, William E., Desprès, Philippe, Arenzana-Seisdedos, Fernando, Dussart, Philippe, Mongkolsapaya, Juthathip, Screaton, Gavin R., Rey, Félix A.

“…Human antibodies in complex with the soluble dimeric form of the dengue virus envelope protein E recognize a quaternary epitope and exhibit strong neutralizing…”
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Immunodominant T-cell responses to dengue virus NS3 are associated with DHF by Duangchinda, Thaneeya, Dejnirattisai, Wanwisa, Vasanawathana, Sirijit, Limpitikul, Wannee, Tangthawornchaikul, Nattaya, Malasit, Prida, Mongkolsapaya, Juthathip, Screaton, Gavin

“…Dengue infections are increasing at an alarming rate in many tropical and subtropical countries, where epidemics can put health care systems under extreme…”
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A haemagglutination test for rapid detection of antibodies to SARS-CoV-2 by Townsend, Alain, Rijal, Pramila, Xiao, Julie, Tan, Tiong Kit, Huang, Kuan-Ying A., Schimanski, Lisa, Huo, Jiandong, Gupta, Nimesh, Rahikainen, Rolle, Matthews, Philippa C., Crook, Derrick, Hoosdally, Sarah, Dunachie, Susanna, Barnes, Eleanor, Street, Teresa, Conlon, Christopher P., Frater, John, Arancibia-Cárcamo, Carolina V., Rudkin, Justine, Stoesser, Nicole, Karpe, Fredrik, Neville, Matthew, Ploeg, Rutger, Oliveira, Marta, Roberts, David J., Lamikanra, Abigail A., Tsang, Hoi Pat, Bown, Abbie, Vipond, Richard, Mentzer, Alexander J., Knight, Julian C., Kwok, Andrew J., Screaton, Gavin R., Mongkolsapaya, Juthathip, Dejnirattisai, Wanwisa, Supasa, Piyada, Klenerman, Paul, Dold, Christina, Baillie, J. Kenneth, Moore, Shona C., Openshaw, Peter J. M., Semple, Malcolm G., Turtle, Lance C. W., Ainsworth, Mark, Allcock, Alice, Beer, Sally, Bibi, Sagida, Skelly, Donal, Stafford, Lizzy, Jeffrey, Katie, O’Donnell, Denise, Clutterbuck, Elizabeth, Espinosa, Alexis, Mendoza, Maria, Georgiou, Dominique, Lockett, Teresa, Martinez, Jose, Perez, Elena, Gallardo Sanchez, Veronica, Scozzafava, Giuseppe, Sobrinodiaz, Alberto, Thraves, Hannah, Joly, Etienne

“…Serological detection of antibodies to SARS-CoV-2 is essential for establishing rates of seroconversion in populations, and for seeking evidence for a level of…”
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Recent advances in understanding dengue [version 1; peer review: 3 approved] by Yacoub, Sophie, Mongkolsapaya, Juthathip, Screaton, Gavin

“…Dengue is an emerging threat to billions of people worldwide. In the last 20 years, the incidence has increased four-fold and this trend appears to be…”
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CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever by Shu, Bo, Ooi, Justin S. G., Tan, Aaron W. K., Ng, Thiam-Seng, Dejnirattisai, Wanwisa, Mongkolsapaya, Juthathip, Fibriansah, Guntur, Shi, Jian, Kostyuchenko, Victor A., Screaton, Gavin R., Lok, Shee-Mei

“…Dengue virus infection can cause dengue hemorrhagic fever (DHF). Dengue NS1 is multifunctional. The intracellular dimeric NS1 (iNS1) forms part of the viral…”
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Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope by Rouvinski, Alexander, Dejnirattisai, Wanwisa, Guardado-Calvo, Pablo, Vaney, Marie-Christine, Sharma, Arvind, Duquerroy, Stéphane, Supasa, Piyada, Wongwiwat, Wiyada, Haouz, Ahmed, Barba-Spaeth, Giovanna, Mongkolsapaya, Juthathip, Rey, Félix A., Screaton, Gavin R.

“…A problem in the search for an efficient vaccine against dengue virus is the immunodominance of the fusion loop epitope (FLE), a segment of the envelope…”
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Generation of SARS-CoV-2 escape mutations by monoclonal antibody therapy by Ragonnet-Cronin, Manon, Nutalai, Rungtiwa, Huo, Jiandong, Dijokaite-Guraliuc, Aiste, Das, Raksha, Tuekprakhon, Aekkachai, Supasa, Piyada, Liu, Chang, Selvaraj, Muneeswaran, Groves, Natalie, Hartman, Hassan, Ellaby, Nicholas, Mark Sutton, J., Bahar, Mohammad W., Zhou, Daming, Fry, Elizabeth, Ren, Jingshan, Brown, Colin, Klenerman, Paul, Dunachie, Susanna J., Mongkolsapaya, Juthathip, Hopkins, Susan, Chand, Meera, Stuart, David I., Screaton, Gavin R., Rokadiya, Sakib

“…COVID-19 patients at risk of severe disease may be treated with neutralising monoclonal antibodies (mAbs). To minimise virus escape from neutralisation these…”
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Neutrophil Activation and Early Features of NET Formation Are Associated With Dengue Virus Infection in Human by Opasawatchai, Anunya, Amornsupawat, Panicha, Jiravejchakul, Natnicha, Chan-In, Wilawan, Spoerk, Nicholas J, Manopwisedjaroen, Khajohnpong, Singhasivanon, Pratap, Yingtaweesak, Tawatchai, Suraamornkul, Swangjit, Mongkolsapaya, Juthathip, Sakuntabhai, Anavaj, Matangkasombut, Ponpan, Loison, Fabien

“…The involvement of the immune system in the protection and pathology of natural dengue virus (DENV) has been extensively studied. However, despite studies that…”
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Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy by Wessel, Alex W., Kose, Nurgun, Bombardi, Robin G., Roy, Vicky, Chantima, Warangkana, Mongkolsapaya, Juthathip, Edeling, Melissa A., Nelson, Christopher A., Bosch, Irene, Alter, Galit, Screaton, Gavin R., Fremont, David H., Crowe, James E., Diamond, Michael S.

“…There are no licensed therapeutics or vaccines available against Zika virus (ZIKV) to counteract its potential for congenital disease. Antibody-based…”
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Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors by López-Camacho, César, Abbink, Peter, Larocca, Rafael A., Dejnirattisai, Wanwisa, Boyd, Michael, Badamchi-Zadeh, Alex, Wallace, Zoë R., Doig, Jennifer, Velazquez, Ricardo Sanchez, Neto, Roberto Dias Lins, Coelho, Danilo F., Kim, Young Chan, Donald, Claire L., Owsianka, Ania, De Lorenzo, Giuditta, Kohl, Alain, Gilbert, Sarah C., Dorrell, Lucy, Mongkolsapaya, Juthathip, Patel, Arvind H., Screaton, Gavin R., Barouch, Dan H., Hill, Adrian V. S., Reyes-Sandoval, Arturo

“…Zika virus (ZIKV) emerged on a global scale and no licensed vaccine ensures long-lasting anti-ZIKV immunity. Here we report the design and comparative…”
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The immunology of Zika Virus by Culshaw, Abigail, Mongkolsapaya, Juthathip, Screaton, Gavin

“…Zika virus (ZIKV) was initially thought to cause only mild, self-limiting symptoms. However, recent outbreaks have been associated with the autoimmune disease…”
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