Search Results - "Mongélard, Fabien"
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Nucleolin is a histone chaperone with FACT-like activity and assists remodeling of nucleosomes
Published in The EMBO journal (19-04-2006)“…Remodeling machines play an essential role in the control of gene expression, but how their activity is regulated is not known. Here we report that the nuclear…”
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2
MacroH2A histone variants maintain nuclear organization and heterochromatin architecture
Published in Journal of cell science (01-05-2017)“…Genetic loss-of-function studies on development, cancer and somatic cell reprogramming have suggested that the group of macroH2A histone variants might…”
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3
Nucleolin Targeting Impairs the Progression of Pancreatic Cancer and Promotes the Normalization of Tumor Vasculature
Published in Cancer research (Chicago, Ill.) (15-12-2016)“…Pancreatic cancer is a highly aggressive tumor, mostly resistant to the standard treatments. Nucleolin is overexpressed in cancers and its inhibition impairs…”
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4
macroH2A1 histone variant represses rDNA transcription
Published in Nucleic acids research (01-01-2014)“…The regulation of ribosomal DNA transcription is an important step for the control of cell growth. Epigenetic marks such as DNA methylation and…”
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Integrated analysis of mRNA and miRNA expression in HeLa cells expressing low levels of Nucleolin
Published in Scientific reports (21-08-2017)“…Nucleolin is an essential protein that plays important roles in the regulation of cell cycle and cell proliferation. Its expression is up regulated in many…”
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Expression of Nucleolin Affects Microtubule Dynamics
Published in PloS one (16-06-2016)“…Nucleolin is present in diverse cellular compartments and is involved in a variety of cellular processes from nucleolar structure and function to intracellular…”
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7
Replication fork polarity gradients revealed by megabase-sized U-shaped replication timing domains in human cell lines
Published in PLoS computational biology (01-04-2012)“…In higher eukaryotes, replication program specification in different cell types remains to be fully understood. We show for seven human cell lines that about…”
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Inactivation of nucleolin leads to nucleolar disruption, cell cycle arrest and defects in centrosome duplication
Published in BMC molecular biology (10-08-2007)“…Nucleolin is a major component of the nucleolus, but is also found in other cell compartments. This protein is involved in various aspects of ribosome…”
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Transcriptional Coactivator and Chromatin Protein PC4 Is Involved in Hippocampal Neurogenesis and Spatial Memory Extinction
Published in The Journal of biological chemistry (23-09-2016)“…Although the elaborate combination of histone and non-histone protein complexes defines chromatin organization and hence regulates numerous nuclear processes,…”
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10
Nucleolin: a multiFACeTed protein
Published in Trends in cell biology (01-02-2007)“…Nucleolin is an abundant, ubiquitously expressed protein that is found in various cell compartments, especially in the nucleolus, of which it is a major…”
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In vivo Study of the Histone Chaperone Activity of Nucleolin by FRAP
Published in Biochemistry Research International (01-01-2011)“…Nucleolin is a major nucleolar protein involved in various aspects of ribosome biogenesis such as regulation of polymerase I transcription, pre-RNA maturation,…”
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Xist Yeast Artificial Chromosome Transgenes Function as X-Inactivation Centers Only in Multicopy Arrays and Not as Single Copies
Published in Molecular and Cellular Biology (01-04-1999)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human XIST Yeast Artificial Chromosome Transgenes Show Partial X Inactivation Center Function in Mouse Embryonic Stem Cells
Published in Proceedings of the National Academy of Sciences - PNAS (08-06-1999)“…Initiation of X chromosome inactivation requires the presence, in cis, of the X inactivation center (XIC). The Xist gene, which lies within the XIC region in…”
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14
Trans-splicing as a Novel Mechanism to Explain Interallelic Complementation in Drosophila
Published in Genetics (Austin) (01-04-2002)“…Two mutant alleles of the same gene, each located in one of the two homologous chromosomes, may in some instances restore the wild-type function of the gene…”
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Interaction of nucleolin with ribosomal RNA genes and its role in RNA polymerase I transcription
Published in Nucleic acids research (01-10-2012)“…Nucleolin is a multi-functional nucleolar protein that is required for ribosomal RNA gene (rRNA) transcription in vivo, but the mechanism by which nucleolin…”
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Nonrandom Distribution of Metaphase AgNOR Staining Patterns on Human Acrocentric Chromosomes
Published in The journal of histochemistry and cytochemistry (01-01-2000)“…The metaphase nucleolar organizer regions (NORs) contain ribosomal genes associated with proteins such as upstream binding factor (UBF) and RNA polymerase I…”
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Centrosomal nucleolin is required for microtubule network organization
Published in Cell cycle (Georgetown, Tex.) (2015)“…Nucleolin is a pleiotropic protein involved in a variety of cellular processes. Although multipolar spindle formation has been observed after nucleolin…”
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3D chromatin conformation correlates with replication timing and is conserved in resting cells
Published in Nucleic acids research (01-10-2012)“…Although chromatin folding is known to be of functional importance to control the gene expression program, less is known regarding its interplay with DNA…”
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Chromatin structure and organization: the relation with gene expression during development and disease
Published in Sub-cellular biochemistry (2013)“…The elementary level of chromatin fiber, namely the nucleofilament, is known to undergo a hierarchical compaction leading to local chromatin loops, then…”
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Characterization of nucleolin K88 acetylation defines a new pool of nucleolin colocalizing with pre-mRNA splicing factors
Published in FEBS letters (01-03-2013)“…► Nucleolin is acetylated in vivo. ► Antibody specific for nucleolin acetylation was developed. ► Acetylated nucleolin is present in nucleoplasmic speckles. ►…”
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