Search Results - "Monfoulet, Laurent"
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Anthocyanins and their gut metabolites attenuate monocyte adhesion and transendothelial migration through nutrigenomic mechanisms regulating endothelial cell permeability
Published in Free radical biology & medicine (20-08-2018)“…Cardioprotective effects of dietary anthocyanins are partly attributed to their ability to maintain endothelial function. However, the underlying cellular and…”
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Anthocyanins and their gut metabolites reduce the adhesion of monocyte to TNFα-activated endothelial cells at physiologically relevant concentrations
Published in Archives of biochemistry and biophysics (01-06-2016)“…An increasing number of evidence suggests a protective role of dietary anthocyanins against cardiovascular diseases. Anthocyanins' extensive metabolism…”
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Metabolomics signatures of plant protein intake: effects of amino acids and compounds associated with plant protein on cardiometabolic health
Published in Current opinion in clinical nutrition and metabolic care (01-03-2023)“…An increase in the plant-based characteristics of the diet is now recommended for human and planetary health. There is growing evidence that plant protein (PP)…”
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Dietary modulation of large extracellular vesicles: the good and the bad for human health
Published in Nutrition reviews (08-04-2022)“…Abstract Extracellular vesicles (EVs) encompassing nanovesicles derived from the endosome system and generated by plasmatic membrane shedding are of increasing…”
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A Meta-Analysis of the Impact of Nutritional Supplementation on Osteoarthritis Symptoms
Published in Nutrients (12-04-2022)“…Conflicting evidence exists concerning the effects of nutrient intake in osteoarthritis (OA). A systematic literature review and meta-analysis were performed…”
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Curcumin modulates endothelial permeability and monocyte transendothelial migration by affecting endothelial cell dynamics
Published in Free radical biology & medicine (01-11-2017)“…Curcumin is a phenolic compound that exhibits beneficial properties for cardiometabolic health. We previously showed that curcumin reduced the infiltration of…”
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Molecular Determinants of the Cardiometabolic Improvements of Dietary Flavanols Identified by an Integrative Analysis of Nutrigenomic Data from a Systematic Review of Animal Studies
Published in Molecular nutrition & food research (01-08-2021)“…Scope: Flavanols are important polyphenols of the human diet with extensive demonstrations of their beneficial effects on cardiometabolic health. They…”
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Targeting the gut to prevent and counteract metabolic disorders and pathologies during aging
Published in Critical reviews in food science and nutrition (21-12-2023)“…Impairment of gut function is one of the explanatory mechanisms of health status decline in elderly population. These impairments involve a decline in gut…”
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The pH in the microenvironment of human mesenchymal stem cells is a critical factor for optimal osteogenesis in tissue-engineered constructs
Published in Tissue engineering. Part A (01-07-2014)“…The present study aimed at elucidating the effect of local pH in the extracellular microenvironment of tissue-engineered (TE) constructs on bone cell functions…”
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Proangiogenic and Prosurvival Functions of Glucose in Human Mesenchymal Stem Cells upon Transplantation
Published in Stem cells (Dayton, Ohio) (01-03-2013)“…A major limitation in the development of cellular therapies using human mesenchymal stem cells (hMSCs) is cell survival post‐transplantation. In this study, we…”
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A systems biology network analysis of nutri(epi)genomic changes in endothelial cells exposed to epicatechin metabolites
Published in Scientific reports (19-10-2018)“…Although vasculo-protective effects of flavan-3-ols are widely accepted today, their impact on endothelial cell functions and molecular mechanisms of action…”
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Thrombin generation in real life bleeding patients on oral anticoagulants reversed (or not) with (activated) prothrombin complex concentrate
Published in Thrombosis research (01-03-2023)“…Bleeding during oral anticoagulant therapy is currently codified by expert guidelines. Monitoring of coagulation during bleeding events is challenging. Our…”
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Featured Article: Deficiency of G-protein coupled receptor 40, a lipid-activated receptor, heightens in vitro- and in vivo-induced murine osteoarthritis
Published in Experimental biology and medicine (Maywood, N.J.) (01-07-2015)“…Osteoarthritis (OA) is an age-related degenerative joint disease. To date, its management is focused on symptoms (pain and inflammation). Studies suggest that…”
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Evaluating the role of orange juice, HESPERidin in vascular HEALTH benefits (HESPER-HEALTH study): protocol for a randomised controlled trial
Published in BMJ open (30-11-2021)“…IntroductionAlthough epidemiological studies associate the consumption of sugary beverages with adverse health effects, human experimental studies have…”
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Ischemia is the prime but not the only cause of human multipotent stromal cell death in tissue-engineered constructs in vivo
Published in Tissue engineering. Part A (01-10-2012)“…Local tissue ischemia is a prime cause responsible for the massive cell death in tissue-engineered (TE) constructs observed postimplantation. To assess the…”
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Impact of Lactic Acid Bacteria Fermentation on (Poly)Phenolic Profile and In Vitro Antioxidant and Anti-Inflammatory Properties of Herbal Infusions
Published in Antioxidants (01-05-2024)“…Recently, the development of functional beverages has been enhanced to promote health and nutritional well-being. Thus, the fermentation of plant foods with…”
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Thyroid hormone receptor β mediates thyroid hormone effects on bone remodeling and bone mass
Published in Journal of bone and mineral research (01-09-2011)“…Excess thyroid hormone (TH) in adults causes osteoporosis and increases fracture risk. However, the mechanisms by which TH affects bone turnover are not…”
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Improving the reporting quality of intervention trials addressing the inter-individual variability in response to the consumption of plant bioactives: quality index and recommendations
Published in European journal of nutrition (01-11-2019)“…Purpose The quality of the study design and data reporting in human trials dealing with the inter-individual variability in response to the consumption of…”
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Nutraceuticals in joint health: animal models as instrumental tools
Published in Drug discovery today (01-10-2014)“…•We examined animal models used for evaluating nutraceutical-based therapies for OA.•Our evidence-based review shows the effectiveness of nutraceuticals in…”
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Effect of apple food matrix on plasma flavan-3-ols distribution and nutrigenomic profile in response to a nutritional challenge in minipigs
Published in Proceedings of the Nutrition Society (2020)“…Food matrix is known to interact with some dietary constituents and microconstituents during digestion. These interactions may potentially affect the…”
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