Search Results - "Monforte, Anna Maria"

Discovery of benzimidazole‐based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis by De Luca, Laura, Ferro, Stefania, Buemi, Maria Rosa, Monforte, Anna‐Maria, Gitto, Rosaria, Schirmeister, Tanja, Maes, Louis, Rescifina, Antonio, Micale, Nicola

“…Chemotherapy is currently the only effective approach to treat all forms of leishmaniasis. However, its effectiveness is severely limited due to high toxicity,…”
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In Vivo Evaluation of Selective Carbonic Anhydrase Inhibitors as Potential Anticonvulsant Agents by Bruno, Elvira, Buemi, Maria R., De Luca, Laura, Ferro, Stefania, Monforte, Anna-Maria, Supuran, Claudiu T., Vullo, Daniela, De Sarro, Giovambattista, Russo, Emilio, Gitto, Rosaria

“…Epilepsy is a common neurological disorder caused by an imbalance between inhibitory and excitatory neurotransmission. It is well known that neuronal…”
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Pharmacophore-Based Design of HIV-1 Integrase Strand-Transfer Inhibitors by Barreca, Maria Letizia, Ferro, Stefania, Rao, Angela, De Luca, Laura, Zappalà, Maria, Monforte, Anna-Maria, Debyser, Zeger, Witvrouw, Myriam, Chimirri, Alba

“…Using a training set of diketo-like acid HIV-1 integrase (IN) strand-transfer inhibitors, a 3D pharmacophore model was derived having quantitative predictive…”
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The Thiazolobenzimidazole TBZE-029 Inhibits Enterovirus Replication by Targeting a Short Region Immediately Downstream from Motif C in the Nonstructural Protein 2C by De Palma, Armando M, Heggermont, Ward, Lanke, Kjerstin, Coutard, Bruno, Bergmann, Mirko, Monforte, Anna-Maria, Canard, Bruno, De Clercq, Erik, Chimirri, Alba, Pürstinger, Gerhard, Rohayem, Jacques, van Kuppeveld, Frank, Neyts, Johan

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains by Barreca, Maria Letizia, Rao, Angela, Luca, Laura De, Iraci, Nunzio, Monforte, Anna-Maria, Maga, Giovanni, Clercq, Erik De, Pannecouque, Christophe, Balzarini, Jan, Chimirri, Alba

“…N 1-arylsulfonyl-1,3-dihydro-2 H-benzimidazol-2-one as a novel template for the design of new anti-HIV agents is reported. Molecular modeling studies led to…”
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Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV-1 agents by Barreca, Maria Letizia, Chimirri, Alba, De Luca, Laura, Monforte, Anna-Maria, Monforte, Pietro, Rao, Angela, Zappalà, Maria, Balzarini, Jan, De Clercq, Erik, Pannecouque, Christophe, Witvrouw, Myriam

“…Design, synthesis and anti-HIV activity of a series of 2,3-diaryl-1,3-thiazolidin-4-ones are reported. Some derivatives proved to be highly effective in…”
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Searching for novel N1-substituted benzimidazol-2-ones as non-nucleoside HIV-1 RT inhibitors by Ferro, Stefania, Buemi, Maria Rosa, De Luca, Laura, Agharbaoui, Fatima E., Pannecouque, Christophe, Monforte, Anna-Maria

“…[Display omitted] Non-nucleoside reverse transcriptase inhibitors (NNRTIs) represent an integral part of the currently available combination antiretroviral…”
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InVivo Evaluation of Selective Carbonic Anhydrase Inhibitors as Potential Anticonvulsant Agents by Bruno, Elvira, Buemi, Maria R, DeLuca, Laura, Ferro, Stefania, Monforte, Anna-Maria, Supuran, Claudiu T, Vullo, Daniela, DeSarro, Giovambattista, Russo, Emilio, Gitto, Rosaria

“…Epilepsy is a common neurological disorder caused by an imbalance between inhibitory and excitatory neurotransmission. It is well known that neuronal…”
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Design and synthesis of N1-aryl-benzimidazoles 2-substituted as novel HIV-1 non-nucleoside reverse transcriptase inhibitors by Monforte, Anna-Maria, Ferro, Stefania, De Luca, Laura, Lo Surdo, Giuseppa, Morreale, Francesca, Pannecouque, Christophe, Balzarini, Jan, Chimirri, Alba

“…A series of novel N1-aryl-2-arylthioacetamido-benzimidazoles were synthesized and evaluated as inhibitors of human immunodeficiency virus type-1 (HIV-1). Some…”
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Simulated human digestion of N1-aryl-2-arylthioacetamidobenzimidazoles and their activity against Herpes-simplex virus 1 in vitro by Mandalari, Giuseppina, Bisignano, Carlo, Smeriglio, Antonella, Denaro, Marcella, Musarra-Pizzo, Maria, Pennisi, Rosamaria, Mancuso, Francesca, Ferro, Stefania, Trombetta, Domenico, Monforte, Anna Maria, Sciortino, Maria Teresa, De Luca, Laura

“…Drug performance in the gastrointestinal tract (GIT) plays a crucial role in determining release and absorption. In the present work, we assessed the in vitro…”
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Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors by Monforte, Anna-Maria, Logoteta, Patrizia, Luca, Laura De, Iraci, Nunzio, Ferro, Stefania, Maga, Giovanni, De Clercq, Erik, Pannecouque, Christophe, Chimirri, Alba

“…A series of novel benzimidazolones and their analogues, characterized by the presence of one or more methyl groups or other bioisosteric moieties at different…”
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Synthesis and in vitro antitumour activity evaluation of 1-aryl-1H, 3H-thiazolo[4,3-b]quinazolines by GRASSO, Silvana, MICALE, Nicola, MONFORTE, Anna-Maria, MONFORTE, Pietro, POLIMENI, Santina, ZAPPALA, Maria

“…A series of 1H,3H-thiazolo[4,3-b]quinazolines (2a-i) were synthesized and evaluated for their in vitro antitumour activity against ca. 60 human tumour cell…”
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Design, synthesis, and structure–activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents by Monforte, Anna-Maria, Logoteta, Patrizia, Ferro, Stefania, Luca, Laura De, Iraci, Nunzio, Maga, Giovanni, Clercq, Erik De, Pannecouque, Christophe, Chimirri, Alba

“…Novel 1,3-dihydrobenzimidazol-2-one analogues were designed, prepared, and evaluated as anti-HIV agents. Synthesis and structure–activity relationships are…”
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Design, Synthesis, Structure−Activity Relationships, and Molecular Modeling Studies of 2,3-Diaryl-1,3-thiazolidin-4-ones as Potent Anti-HIV Agents by Barreca, Maria L, Balzarini, Jan, Chimirri, Alba, Clercq, Erik De, Luca, Laura De, Höltje, Hans Dieter, Höltje, Monika, Monforte, Anna Maria, Monforte, Pietro, Pannecouque, Christophe, Rao, Angela, Zappalà, Maria

“…Starting from 1H,3H-thiazolo[3,4-a]benzimidazoles (TBZs), we performed the design, synthesis, and the structure−activity relationship studies of a series of…”
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Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors by MONFORTE, Anna-Maria, RAO, Angela, CHIMIRRI, Alba, LOGOTETA, Patrizia, FERRA, Stefania, DE LUCA, Laura, LETIZIA BARRECA, Maria, IRACI, Nunzio, MAGA, Giovanni, DE CLERCQ, Erik, PANNECOUQUE, Christophe

“…Several N(1)-substituted 1,3-dihydro-2H-benzimidazol-2-ones were synthesized and evaluated as anti-HIV agents. Some of them proved to be highly effective in…”
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Slow binding–tight binding interaction between benzimidazol-2-one inhibitors and HIV-1 reverse transcriptase containing the lysine 103 to asparagine mutation by Samuele, Alberta, Crespan, Emmanuele, Vitellaro, Samanta, Monforte, Anna-Maria, Logoteta, Patrizia, Chimirri, Alba, Maga, Giovanni

“…Novel benzimidazol-2-one non-nucleoside reverse transcriptase inhibitors (NNRTIs) have been recently identified, through rational structure-based molecular…”
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Anti-enterovirus activity and structure-activity relationship of a series of 2,6-dihalophenyl-substituted 1H,3H-thiazolo[3,4-a]benzimidazoles by De Palma, Armando M, Heggermont, Ward, Leyssen, Pieter, Pürstinger, Gerhard, Wimmer, Eva, De Clercq, Erik, Rao, Angela, Monforte, Anna-Maria, Chimirri, Alba, Neyts, Johan

“…Despite the fact that enteroviruses are implicated in a variety of human diseases, there is no approved therapy for the treatment of enteroviral infections…”
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Computational Strategies in Discovering Novel Non-nucleoside Inhibitors of HIV-1 RT by Barreca, Maria Letizia, Rao, Angela, De Luca, Laura, Zappalà, Maria, Monforte, Anna-Maria, Maga, Giovanni, Pannecouque, Christophe, Balzarini, Jan, De Clercq, Erik, Chimirri, Alba, Monforte, Pietro

“…A three-dimensional common feature pharmacophore model was developed using the X-ray structure of RT/non-nucleoside inhibitor (NNRTI) complexes. Starting from…”
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Synthesis and Antitumour Activity of 1H,3H-Thiazolo[3,4-a]benzimidazole Derivatives by Chimirri, Alba, Monforte, Pietro, Musumeci, Laura, Rao, Angela, Zappalà, Maria, Monforte, Anna-Maria

“…A series of 1H,3H‐thiazolo[3,4‐a]benzimidazoles were synthesized and tested for their in vitro antitumour activity against 60 human tumour cell lines. Some…”
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Synthesis and Structural Features of New Cyclofunctionalized Benzimidazoles by Chimirri, Alba, Maria Monforte, Anna, Monforte, Pietro, Nicolò, Francesco, Rao, Angela, Zappalà, Maria

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