Search Results - "Monette, M."

Commentary on “Sex and Gender Differences in Clinical Pharmacology: Implications for Transgender Medicine” by Cotreau, Monette M.

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Cultural Considerations in Palliative Care Provision: A Scoping Review of Canadian Literature by Monette, Erynn M.

“…Background: Palliative care, a division of health care that provides treatment to patients facing terminal or incurable illness, prioritizes maintaining…”
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The influence of age and sex on the clearance of cytochrome P450 3A substrates by COTREAU, Monette M, VON MOLTKE, Lisa L, GREENBLATT, David J

“…Cytochrome P450s (CYPs) are an important family of enzymes in the metabolism of many therapeutic agents and endogenous metabolic reactions. The CYP3A subfamily…”
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Informing 'good' global health research partnerships: A scoping review of guiding principles by Monette, Erynn M., McHugh, David, Smith, Maxwell J., Canas, Eugenia, Jabo, Nicole, Henley, Phaedra, Nouvet, Elysée

“…Background: Several sets of principles have been proposed to guide global health research partnerships and mitigate inequities inadvertently caused by them…”
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Biologic and Clinical Activity of Tivozanib (AV-951, KRN-951), a Selective Inhibitor of VEGF Receptor-1, -2, and -3 Tyrosine Kinases, in a 4-Week-On, 2-Week-Off Schedule in Patients with Advanced Solid Tumors by ESKENS, Ferry A. L. M, DE JONGE, Maja J. A, VERWEIJ, Jaap, BHARGAVA, Pankaj, ISOE, Toshiyuki, COTREAU, Monette M, ESTEVES, Brooke, HAYASHI, Kunihiko, BURGER, Herman, THOMEER, Maarten, VAN DOORN, Leni

“…To assess the maximum tolerated dose (MTD)/dose-limiting toxicities (DLT), safety, pharmacokinetics, and pharmacodynamics of tivozanib, a potent and selective…”
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Comparison of Human and Rat Uterine Leiomyomata: Identification of a Dysregulated Mammalian Target of Rapamycin Pathway by CRABTREE, Judy S, JELINSKY, Scott A, DAVE, Bhuvanesh, BROADDUS, Russell R, BROWN, Eugene L, WENLING KAO, SKOTNICKI, Jerauld S, ABOU-GHARBIA, Magid, WINNEKER, Richard C, WALKER, Cheryl L, HARRIS, Heather A, CHOE, Sung E, COTREAU, Monette M, KIMBERLAND, Michelle L, WILSON, Ewa, SARAF, Kathryn A, WEI LIU, MCCAMPBELL, Adrienne S

“…Uterine leiomyomata, or fibroids, are benign tumors of the uterine myometrium that significantly affect up to 30% of reproductive-age women. Despite being the…”
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Developing antisense oligonucleotide and short-interfering RNA therapeutics - a few considerations by Cotreau, Monette M.

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Molecular Classification of Crohn's Disease and Ulcerative Colitis Patients Using Transcriptional Profiles in Peripheral Blood Mononuclear Cells by Burczynski, Michael E., Peterson, Ron L., Twine, Natalie C., Zuberek, Krystyna A., Brodeur, Brendan J., Casciotti, Lori, Maganti, Vasu, Reddy, Padma S., Strahs, Andrew, Immermann, Fred, Spinelli, Walter, Schwertschlag, Ulrich, Slager, Anna M., Cotreau, Monette M., Dorner, Andrew J.

“…Ulcerative colitis (UC) and Crohn's disease (CD) are common inflammatory bowel diseases producing intestinal inflammation and tissue damage. Although emerging…”
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Quality of life during the course of cancer treatment in older newly diagnosed patients. Results of a prospective pilot study by Puts, M.T.E., Monette, J., Girre, V., Wolfson, C., Monette, M., Batist, G., Bergman, H.

“…The aim of this prospective study was to report the quality of life (QoL) of older cancer patients during the first year after diagnosis and factors…”
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Effects of ketoconazole or rifampin on the pharmacokinetics of tivozanib hydrochloride, a vascular endothelial growth factor receptor tyrosine kinase inhibitor by Cotreau, Monette M., Siebers, Nicholas M., Miller, James, Strahs, Andrew L., Slichenmyer, William

“…The vascular endothelial growth factor (VEGF) pathway is associated with the promotion of endothelial cell proliferation, migration, and survival necessary for…”
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Reliability, validity, and applicability of the Quebec User Evaluation of Satisfaction with assistive Technology (QUEST 2.0) for adults with multiple sclerosis by Demers, L., Monette, M., Lapierre, Y., Arnold, D. L., Wolfson, C.

“…Purpose : To investigate the measurement properties of the Quebec User Evaluation of Satisfaction with assistive Technology (QUEST 2.0) with respect to…”
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Local repair of stoma prolapse: Case report of an in vivo application of linear stapler devices by Monette, Margaret M, Harney, Rodney T, Morris, Melanie S, Chu, Daniel I

“…Abstract Introduction One of the most common late complications following stoma construction is prolapse. Although the majority of prolapse can be managed…”
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Evidence for episodic acidification effects on migrating Atlantic salmon Salmo salar smolts by Kelly, J. T., Lerner, D. T., O'Dea, M. F., Regish, A. M., Monette, M. Y., Hawkes, J. P., Nislow, K. H., McCormick, S. D.

“…Field studies were conducted to determine levels of gill aluminium as an index of acidification effects on migrating Atlantic salmon Salmo salar smolts in the…”
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Does frailty predict hospitalization, emergency department visits, and visits to the general practitioner in older newly-diagnosed cancer patients? Results of a prospective pilot study by Puts, M.T.E, Monette, J, Girre, V, Wolfson, C, Monette, M, Batist, G, Bergman, H

“…Abstract Research on the use of health care by older newly-diagnosed cancer patients is sparse. We investigated whether frailty predicts hospitalization,…”
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In vitro, pharmacokinetic, and pharmacodynamic interactions of ketoconazole and midazolam in the rat by Kotegawa, Tsutomu, Laurijssens, Bart E, Von Moltke, Lisa L, Cotreau, Monette M, Perloff, Michael D, Venkatakrishnan, Karthik, Warrington, Jill S, Granda, Brian W, Harmatz, Jerold S, Greenblatt, David J

“…Interactions of midazolam and ketoconazole were studied in vivo and in vitro in rats. Ketoconazole (total dose of 15 mg/kg intraperitoneally) reduced clearance…”
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A Phase I cardiac safety and pharmacokinetic study of tivozanib hydrochloride in patients with advanced solid tumors by Moore, Kathleen, Infante, Jeffrey R., Cotreau, Monette M., Wilson, Lindsey, Strahs, Andrew L., Vargo, Dennis L., Chadha, Manpreet

“…Tivozanib hydrochloride (tivozanib) is a potent, selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors, with a long…”
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Clinical experience of cancer specialists and geriatricians involved in cancer care of older patients: A qualitative study by Puts, M.T.E, Girre, V, Monette, J, Wolfson, C, Monette, M, Batist, G, Bergman, H

“…Abstract Introduction Cancer is an important health problem in older persons. The aim of this study was to explore how cancer specialists and geriatricians…”
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A Phase Ib Study of the VEGF Receptor Tyrosine Kinase Inhibitor Tivozanib and Modified FOLFOX-6 in Patients With Advanced Gastrointestinal Malignancies by Oldenhuis, Corina N, Loos, Walter J, Esteves, Brooke, van Doorn, Leni, Cotreau, Monette M, Strahs, Andrew L, den Hollander, Martha W, Gietema, Jourik A, de Vries, Elisabeth G.E, Eskens, Ferry A.L.M

“…Micro-Abstract Combining a modified (m)FOLFOX-6 (leucovorin, 5-fluorouracil [5-FU], and 85 mg/kg2 oxaliplatin) regimen with antiangiogenic therapy is a…”
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The Antiparasitic Moxidectin: Safety, Tolerability, and Pharmacokinetics in Humans by Cotreau, Monette M., Warren, Sarah, Ryan, John L., Fleckenstein, Lawrence, Vanapalli, Sreenivasa R., Brown, Kenneth R., Rock, David, Chen, Chieh-Yu, Schwertschlag, Ullrich S.

“…A study in healthy male volunteers was completed to evaluate the safety, tolerability, and pharmacokinetics of a single oral dose of the antiparasitic…”
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Solid-State NMR Characterization and Determination of the Orientational Order of a Nematogen by Narasimhaswamy, T, Monette, M, Lee, D. K, Ramamoorthy, A

“…Thermotropic liquid crystalline compounds are of considerable importance due to their potential applications as advanced functional materials. A mesogen…”
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