Search Results - "Moneta, D."
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Powerful Anticonvulsant Action of IL-1 Receptor Antagonist on Intracerebral Injection and Astrocytic Overexpression in Mice
Published in Proceedings of the National Academy of Sciences - PNAS (10-10-2000)“…IL-1β and its endogenous receptor antagonist (IL-1Ra) are rapidly induced by seizures in the rodent hippocampus. Exogenously applied IL-1β prolongs seizures in…”
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2
Somatostatin receptor subtypes 2 and 4 affect seizure susceptibility and hippocampal excitatory neurotransmission in mice
Published in The European journal of neuroscience (01-09-2002)“…We have investigated the role of somatostatin receptor subtypes sst2 and sst4 in limbic seizures and glutamate‐mediated neurotransmission in mouse hippocampus…”
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Dynamic induction of the long pentraxin PTX3 in the CNS after limbic seizures: evidence for a protective role in seizure-induced neurodegeneration
Published in Neuroscience (01-01-2001)“…Pentraxin 3, a prototypic long pentraxin, is induced by proinflammatory signals in the brain. Inflammatory cytokines are rapidly induced in glia by epileptic…”
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Seizure susceptibility and epileptogenesis are decreased in transgenic rats overexpressing neuropeptide Y
Published in Neuroscience (01-01-2002)“…Functional studies in epileptic tissue indicate that neuropeptide Y and some of its peptide analogs potently inhibit seizure activity. We investigated seizure…”
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Brain-derived neurotrophic factor immunoreactivity in the limbic system of rats after acute seizures and during spontaneous convulsions: temporal evolution of changes as compared to neuropeptide Y
Published in Neuroscience (01-01-1999)“…Seizures increase the synthesis of brain-derived neurotrophic factor in forebrain areas, suggesting this neurotrophin has biological actions in epileptic…”
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Serum trypsinogen activation peptide in the assessment of the diagnosis and severity of acute pancreatic damage: a pilot study using a new determination technique
Published in Pancreas (01-11-2004)“…To evaluate the clinical value of a new direct and competitive immunoassay for trypsinogen activation peptide (TAP) determination in acute pancreatitis (AP)…”
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Plastic Changes in Neuropeptide Y Receptor Subtypes in Experimental Models of Limbic Seizures
Published in Epilepsia (Copenhagen) (01-01-2000)“…Purpose: Neuropetide Y (NPY)‐mediated neuro‐transmission in the hippocampus is altered by limbic seizures. The functional consequences of this change are still…”
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Journal Article Conference Proceeding -
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Predicting the maximum-tolerated dose of PNU-159548 (4-demethoxy-3′-deamino-3′-aziridinyl-4′-methylsulphonyl-daunorubicin) in humans using CFU-GM clonogenic assays and prospective validation
Published in European journal of cancer (1990) (01-03-2003)“…A haematotoxicity model was proposed by Parchment in 1998 to predict the maximum-tolerated dose (MTD) in humans of myelosuppressive antitumour agents by…”
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9
PNU-159548, a novel cytotoxic antitumor agent with a low cardiotoxic potential
Published in Cancer chemotherapy and pharmacology (01-04-2001)“…PNU-159548 (4-demethoxy-3'-deamino-3'aziridinyl-4'-methylsulphonyl-daunorubicin), a derivative of the anticancer idarubicin, has a broad spectrum of…”
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10
Interleukin-1β Immunoreactivity and Microglia Are Enhanced in the Rat Hippocampus by Focal Kainate Application: Functional Evidence for Enhancement of Electrographic Seizures
Published in The Journal of neuroscience (15-06-1999)“…Using immunocytochemistry and ELISA, we investigated the production of interleukin (IL)-1β in the rat hippocampus after focal application of kainic acid…”
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Functional Role of Inflammatory Cytokines and Antiinflammatory Molecules in Seizures and Epileptogenesis
Published in Epilepsia (Copenhagen) (01-01-2002)“…Purpose: We investigated the changes in the expression of proinflammatory cytokines and related molecules in the rodent hippocampus after the induction of…”
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Journal Article Conference Proceeding -
12
Inflammatory cytokines and related genes are induced in the rat hippocampus by limbic status epilepticus
Published in The European journal of neuroscience (01-07-2000)“…Limbic status epilepticus was induced in rats by unilateral 60‐min electrical stimulation of the CA3 region of the ventral hippocampus. As assessed by RT‐PCR…”
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13
Optimal management of an electric storage system with multiple network connection points
Published in 2017 IEEE PES Innovative Smart Grid Technologies Conference Europe (ISGT-Europe) (01-09-2017)“…Active Distribution Networks (ADNs), which are distribution networks with high presence of Distributed Generation (DG) - in particular from Renewable Energy…”
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Conference Proceeding -
14
Delayed respiratory depression after alfentanil
Published in Anesthesiology (Philadelphia) (01-10-1988)Get full text
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15
Functional role of proinflammatory and anti-inflammatory cytokines in seizures
Published in Advances in experimental medicine and biology (2004)“…Recent evidence has shown that proinflammatory and anti-inflammatory molecules are synthesized during epileptic activity in glial cells in CNS regions where…”
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Brostallicin: a new concept in minor groove DNA binder development
Published in Anti-cancer drugs (01-01-2004)“…Brostallicin is a bromoacryloyl derivative of distamycin A, which has shown very promising preclinical activity against a variety of human tumors both in vitro…”
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Immunohistochemical evaluation of bone marrow biopsies in myelodysplastic syndromes
Published in Haematologia (1991)“…Immunohistochemical studies were performed with monoclonal antibodies (MAbs) reactive on paraffin embedded bone marrow biopsies in 19 patients with…”
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Pharmacological and toxicological aspects of 4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548) : A novel antineoplastic agent
Published in Cancer research (Chicago, Ill.) (01-03-2001)“…4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548) belongs to a novel class of antitumor compounds (termed alkycyclines) and is…”
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Energy conservation and smartgrids: New challenge for multimetering infrastructures
Published in 2009 IEEE Bucharest PowerTech (01-06-2009)“…Operation of future power systems will be shared between central and distributed generators. Control of distributed generators will need to be aggregated to…”
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Conference Proceeding -
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The antitumor efficacy of cytotoxic drugs is potentiated by treatment with PNU 145156E, a growth-factor-complexing molecule
Published in Cancer chemotherapy and pharmacology (1999)“…PNU 145156E (formerly FCE 26644) is a noncytotoxic molecule whose antitumor activity is exerted through the formation of a reversible complex with…”
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