Search Results - "Monducci, Davide"

Comparative optimization of combinatorial CRISPR screens by Li, Ruitong, Klingbeil, Olaf, Monducci, Davide, Young, Michael J., Rodriguez, Diego J., Bayyat, Zaid, Dempster, Joshua M., Kesar, Devishi, Yang, Xiaoping, Zamanighomi, Mahdi, Vakoc, Christopher R., Ito, Takahiro, Sellers, William R.

“…Combinatorial CRISPR technologies have emerged as a transformative approach to systematically probe genetic interactions and dependencies of redundant gene…”
Get full text

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers by Ito, Takahiro, Young, Michael J., Li, Ruitong, Jain, Sidharth, Wernitznig, Andreas, Krill-Burger, John M., Lemke, Christopher T., Monducci, Davide, Rodriguez, Diego J., Chang, Liang, Dutta, Sanjukta, Pal, Debjani, Paolella, Brenton R., Rothberg, Michael V., Root, David E., Johannessen, Cory M., Parida, Laxmi, Getz, Gad, Vazquez, Francisca, Doench, John G., Zamanighomi, Mahdi, Sellers, William R.

“…Although single-gene perturbation screens have revealed a number of new targets, vulnerabilities specific to frequently altered drivers have not been…”
Get full text

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers by Ito, Takahiro, Young, Michael J, Li, Ruitong, Jain, Sidharth, Wernitznig, Andreas, Krill-Burger, John M, Lemke, Christopher T, Monducci, Davide, Rodriguez, Diego J, Chang, Liang, Dutta, Sanjukta, Pal, Debjani, Paolella, Brenton R, Rothberg, Michael V, Root, David E, Johannessen, Cory M, Parida, Laxmi, Getz, Gad, Vazquez, Francisca, Doench, John G, Zamanighomi, Mahdi, Sellers, William R

“…Although single-gene perturbation screens have revealed a number of new targets, vulnerabilities specific to frequently altered drivers have not been…”
Get full text