Search Results - "Mondragón, Estefanía"
-
1
Molecular sensing by the aptamer domain of the FMN riboswitch: a general model for ligand binding by conformational selection
Published in Nucleic acids research (01-10-2011)“…Understanding the nature of the free state of riboswitch aptamers is important for illuminating common themes in gene regulation by riboswitches. Prior…”
Get full text
Journal Article -
2
Structure–Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch
Published in ACS chemical biology (19-10-2018)“…The flavin mononucleotide (FMN) riboswitch is an emerging target for the development of novel RNA-targeting antibiotics. We previously discovered an FMN…”
Get full text
Journal Article -
3
Anti-Transcription Factor RNA Aptamers as Potential Therapeutics
Published in Nucleic acid therapeutics (01-02-2016)“…Transcription factors (TFs) are DNA-binding proteins that play critical roles in regulating gene expression. These proteins control all major cellular…”
Get more information
Journal Article -
4
RNA aptamer inhibitors of a restriction endonuclease
Published in Nucleic acids research (03-09-2015)“…Restriction endonucleases (REases) recognize and cleave short palindromic DNA sequences, protecting bacterial cells against bacteriophage infection by…”
Get full text
Journal Article -
5
Binding specificities of human RNA-binding proteins toward structured and linear RNA sequences
Published in Genome research (01-07-2020)“…RNA-binding proteins (RBPs) regulate RNA metabolism at multiple levels by affecting splicing of nascent transcripts, RNA folding, base modification, transport,…”
Get full text
Journal Article -
6
Structure-activity relationship of flavin analogs that target the FMN riboswitch
Published in ACS chemical biology (20-09-2018)“…The flavin mononucleotide (FMN) riboswitch is an emerging target for the development of novel RNA-targeting antibiotics. We previously discovered an FMN…”
Get full text
Journal Article -
7
Discrimination between Closely Related Cellular Metabolites by the SAM-I Riboswitch
Published in Journal of molecular biology (26-02-2010)“…The SAM-I riboswitch is a cis-acting element of genetic control found in bacterial mRNAs that specifically binds S-adenosylmethionine (SAM). We previously…”
Get full text
Journal Article -
8
RNA aptamer inhibitors for DNA binding proteins
Published 2015“…The main purpose of this thesis is to summarize my five years of doctoral research training focused on small RNA oligonucleotide molecules termed aptamers,…”
Get full text
Dissertation -
9
An Ace in the Hole
Published in Structure (London) (08-08-2012)“…In this issue of Structure, Tesmer and coworkers report the structure of a small RNA aptamer in an inhibitory complex with a G protein receptor kinase. The…”
Get full text
Journal Article