Search Results - "Mondon, Martine"
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Access to l- and d-Iminosugar C-Glycosides from a d-gluco-Derived 6-Azidolactol Exploiting a Ring Isomerization/Alkylation Strategy
Published in Organic letters (03-02-2012)“…A flexible synthetic access to six-membered l- and d-iminosugar C-glycosides is reported starting from the easily available…”
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Synthesis of cyclonucleosides having a C–C bridge
Published in Tetrahedron (04-08-2008)“…The synthesis of cyclonucleosides having a C–C bridge is reviewed. The report contains 54 references [Display omitted]…”
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Selective trihydroxyazepane NagZ inhibitors increase sensitivity of Pseudomonas aeruginosa to β-lactams
Published in Chemical communications (Cambridge, England) (01-01-2013)“…AmpC β-lactamase confers resistance to β-lactam antibiotics in many Gram negative bacteria. Inducible expression of AmpC requires an N-acetylglucosaminidase…”
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Synthesis and structure of novel cyclonucleoside analogues of uridine
Published in Tetrahedron (11-08-2008)“…Novel cyclonucleoside analogues of uridine having pentylene and hexylene linker between the 5′-O and 3-N positions (thereby generating a 13- and 14-membered…”
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Novel triazolyl derivatives for acidic release of amines
Published in Tetrahedron (2011)“…Triazolyl derivatives of amines were prepared using click chemistry and evaluated as releasing systems in mildly acidic environments. Triazolylcarbamates and…”
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Triazolyl Derivatives for Acidic Release of Alcohols
Published in European Journal of Organic Chemistry (01-04-2011)“…New triazolyl‐based carbonates and ethers have been investigated as potential alcohol‐releasing systems under mild acidic conditions. Triazolyl carbonates…”
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Book Review Journal Article -
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Skeletal rearrangement of seven-membered iminosugars: Synthesis of (−)-adenophorine, (−)-1-epi-adenophorine and derivatives and evaluation as glycosidase inhibitors
Published in Bioorganic & medicinal chemistry (15-08-2013)“…An alternative synthetic strategy towards (−)-adenophorine based on a tandem Staudinger/azaWittig/alkylation/ring contraction sequence is reported allowing…”
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Towards a stable noeuromycin analog with a d-manno configuration: Synthesis and glycosidase inhibition of d-manno-like tri- and tetrahydroxylated azepanes
Published in Bioorganic & medicinal chemistry (15-01-2012)“…Noeuromycin is a highly potent albeit unstable glycosidase inhibitor due to its hemiaminal function. While stable d-gluco-like analogs have been reported, no…”
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Synthetic studies on a phenyl-laulimalide analogue
Published in Tetrahedron letters (20-11-2006)“…An analogue of the paclitaxel-like antimicrotubule agent laulimalide with a phenyl in place of the dihydropyran has been synthesized. The fragments C 1–C 14…”
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Synthesis of a novel uridine analogue and its use in attempts to form new cyclonucleosides using ring-closing metathesis
Published in Science China. Chemistry (01-09-2010)“…One novel nucleoside analogue having a hex-5-enyl group and an allyl group in the 5′-C and 3-N position was synthesized regio- and diastereoselectively from d…”
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Prodrugs of Anthracyclines for Use in Antibody-Directed Enzyme Prodrug Therapy
Published in Journal of medicinal chemistry (10-09-1998)“…A series of new prodrugs of daunorubicin and doxorubicin which are candidates for antibody-directed enzyme prodrug therapy (ADEPT) is reported. These compounds…”
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Synthesis of quinone and xanthone analogs of rhein
Published in Tetrahedron (29-10-2001)“…A new strategy based on carbonylation of aryl triflates has been developed to prepare 7-methyl rhein from emodin and new xanthone analogs of rhein. This…”
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Selective cross-metathesis of 2-allylphenols with styrenes
Published in Tetrahedron letters (08-10-2001)Get full text
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Synthesis and cytotoxic activity of tetracenomycin d and of saintopin analogues
Published in Bioorganic & medicinal chemistry (01-02-2002)“…Regiospecific synthesis of title compounds is based either on cycloaddition of ketene acetals derived from Hagemann's ester or of homophthalic anhydrides…”
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Diels-Alder reaction of 4-bromo-6-spiroepoxycyclohexa-2,4-dienone with electron-rich and neutral dienophiles
Published in Tetrahedron (08-01-1999)“…Spirodienone 1, prepared by Adler-Becker oxidation of 4-bromo-2-hydroxymethylphenol, undergoes [4+2] cycloaddition with various dienophiles (enol ethers, enol…”
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Density Functional Study of π Facial Selectivity in Diels−Alder Reactions
Published in Journal of organic chemistry (17-11-2000)Get full text
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Release of the cyano moiety in the crystal structure of N‐cyanomethyl‐N‐(2‐methoxyethyl)‐daunomycin complexed with d(CGATCG)
Published in European journal of biochemistry (01-01-2000)“…Doxorubicin is among the most widely used anthracycline in cancer chemotherapy. In an attempt to avoid the cardiotoxicity and drug resistance of doxorubicin…”
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