Search Results - "Mondal, Rubina"
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Temporal and environmental drivers of fish-community structure in tropical streams from two contrasting regions in India
Published in PloS one (09-04-2020)“…Environmental and anthropogenic factors are known to drive fish community structure in aquatic systems across the world. This study investigates fish…”
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Comparison of regression-based and machine learning techniques to explain alpha diversity of fish communities in streams of central and eastern India
Published in Ecological indicators (01-10-2021)“…[Display omitted] •Predictive powers of four statistical modelling methods were compared.•Artificial neural networks best modeled relations between species and…”
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Different mechanisms drive beta diversity of freshwater fishes across similar ecoregions in India
Published in Aquatic sciences (01-04-2022)“…As an important component of overall diversity, β-diversity is driven by spatial and temporal variability of several ecological factors. While changes to…”
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Interviews with Indian Animal Shelter Staff: Similarities and Differences in Challenges and Resiliency Factors Compared to Western Counterparts
Published in Animals (Basel) (26-09-2022)“…Animal shelters in India are at the forefront of efforts to improve free-ranging dog welfare and tackle animal overpopulation. In terms of cultural and…”
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Discovery of ABT-267, a Pan-Genotypic Inhibitor of HCV NS5A
Published in Journal of medicinal chemistry (13-03-2014)“…We describe here N-phenylpyrrolidine-based inhibitors of HCV NS5A with excellent potency, metabolic stability, and pharmacokinetics. Compounds with 2S,5S…”
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Identification of host genes involved in hepatitis C virus replication by small interfering RNA technology
Published in Hepatology (Baltimore, Md.) (01-06-2007)“…Hepatitis C virus (HCV) replication is highly dependent on host cell factors. Identification of these host factors not only facilitates understanding of the…”
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Wild Zebrafish Sentinels: Biological Monitoring of Site Differences Using Behavior and Morphology
Published in Toxics (Basel) (12-07-2021)“…Environmental change poses a devastating risk to human and environmental health. Rapid assessment of water conditions is necessary for monitoring, evaluating,…”
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Mutations Conferring Resistance to a Hepatitis C Virus (HCV) RNA-Dependent RNA Polymerase Inhibitor Alone or in Combination with an HCV Serine Protease Inhibitor In Vitro
Published in Antimicrobial Agents and Chemotherapy (01-10-2005)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The human-animal bond and at-home behaviours of adopted Indian free-ranging dogs
Published in Applied animal behaviour science (01-11-2023)Get full text
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In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor
Published in Antimicrobial agents and chemotherapy (01-03-2015)“…Dasabuvir (ABT-333) is a nonnucleoside inhibitor of the RNA-dependent RNA polymerase encoded by the hepatitis C virus (HCV) NS5B gene. Dasabuvir inhibited…”
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Highlights of the Structure–Activity Relationships of Benzimidazole Linked Pyrrolidines Leading to the Discovery of the Hepatitis C Virus NS5A Inhibitor Pibrentasvir (ABT-530)
Published in Journal of medicinal chemistry (10-05-2018)“…Curative interferon and ribavirin sparing treatments for hepatitis C virus (HCV)-infected patients require a combination of mechanistically orthogonal direct…”
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Synthesis and Biological Characterization of Aryl Uracil Inhibitors of Hepatitis C Virus NS5B Polymerase: Discovery of ABT-072, a trans-Stilbene Analog with Good Oral Bioavailability
Published in Journal of medicinal chemistry (08-02-2018)“…ABT-072 is a non-nucleoside HCV NS5B polymerase inhibitor that was discovered as part of a program to identify new direct-acting antivirals (DAAs) for the…”
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Discovery of fluorobenzimidazole HCV NS5A inhibitors
Published in Bioorganic & medicinal chemistry letters (15-11-2016)“…[Display omitted] Research toward a next-generation HCV NS5A inhibitor has identified fluorobenzimidazole analogs that demonstrate potent, broad-genotype in…”
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High potency improvements to weak aryl uracil HCV polymerase inhibitor leads
Published in Bioorganic & medicinal chemistry letters (01-08-2013)“…Described herein is the development of a potent non-nucleoside, small molecule inhibitor of genotype 1 HCV NS5B Polymerase. A 23μM inhibitor that was active…”
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Synthesis and Biological Characterization of B-Ring Amino Analogues of Potent Benzothiadiazine Hepatitis C Virus Polymerase Inhibitors
Published in Journal of medicinal chemistry (28-05-2009)“…Benzothiadiazine inhibitors of the HCV NS5B RNA-dependent RNA polymerase are an important class of non-nucleoside inhibitors that have received considerable…”
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Aryl uracil inhibitors of hepatitis C virus NS5B polymerase: Synthesis and characterization of analogs with a fused 5,6-bicyclic ring motif
Published in Bioorganic & medicinal chemistry letters (15-06-2013)“…The synthesis and structure–activity relationships of a novel aryl uracil series which contains a fused 5,6-bicyclic ring unit for HCV NS5B inhibition is…”
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Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well
Published in Antiviral research (01-04-2009)“…The Hepatitis C (HCV) replicon system is a useful tool for the high-volume screening of inhibitors of HCV replication. In this report, a cell-based assay has…”
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A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations
Published in Journal of virological methods (01-11-2007)“…Hepatitis C virus (HCV) replicon-based shuttle vectors that permit phenotypes of NS5B polymerase genes from a large number of patient isolates to be rapidly…”
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