Search Results - "Mondal, Anupam Kumar"
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Comparative Genomics of Host-Symbiont and Free-Living Oceanobacillus Species
Published in Genome biology and evolution (01-05-2017)“…Survival in a given environment requires specific functions, so genomic variation is anticipated within in individual taxonomic groups that exhibit a large…”
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Expression profiling of lymph nodes in tuberculosis patients reveal inflammatory milieu at site of infection
Published in Scientific reports (15-10-2015)“…Extrapulmonary manifestations constitute 15 to 20% of tuberculosis cases, with lymph node tuberculosis (LNTB) as the most common form of infection. However,…”
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Integration host factor of Mycobacterium tuberculosis, mIHF, compacts DNA by a bending mechanism
Published in PloS one (26-07-2013)“…The bacterial chromosomal DNA is folded into a compact structure called as 'nucleoid' so that the bacterial genome can be accommodated inside the cell. The…”
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4
Multiomics analyses reveal early metabolic imbalance and mitochondrial stress in neonatal photoreceptors leading to cell death in Pde6brd1/rd1 mouse model of retinal degeneration
Published in Human molecular genetics (07-07-2022)“…Abstract Retinal diseases exhibit extensive genetic heterogeneity and complex etiology with varying onset and severity. Mutations in over 200 genes can lead to…”
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Discovery of rare protein-coding genes in model methylotroph Methylobacterium extorquens AM1
Published in Proteomics (Weinheim) (01-12-2014)“…Proteogenomics involves the use of MS to refine annotation of protein‐coding genes and discover genes in a genome. We carried out comprehensive proteogenomic…”
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Adipocyte Model of Mycobacterium tuberculosis Infection Reveals Differential Availability of Iron to Bacilli in the Lipid-Rich Caseous Environment
Published in Infection and immunity (01-06-2018)“…, a successful human pathogen, utilizes multiple carbon sources from the host but adapts to a fatty-acid-rich environment We sought to delineate the…”
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Proteogenomics of rare taxonomic phyla: A prospective treasure trove of protein coding genes
Published in Proteomics (Weinheim) (01-01-2016)“…Sustainable innovations in sequencing technologies have resulted in a torrent of microbial genome sequencing projects. However, the prokaryotic genomes…”
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Comparative Genomic Analysis of Mycobacteriaceae Reveals Horizontal Gene Transfer-Mediated Evolution of the CRISPR-Cas System in the Mycobacterium tuberculosis Complex
Published in mSystems (19-01-2021)“…Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) genes are conserved genetic elements in many prokaryotes,…”
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Extensive copy number variations in admixed Indian population of African ancestry: potential involvement in adaptation
Published in Genome biology and evolution (01-12-2014)“…Admixture mapping has been enormously resourceful in identifying genetic variations linked to phenotypes, adaptation, and diseases. In this study through…”
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Comparative Genomic Analysis of italic toggle="yes">Mycobacteriaceae /italic> Reveals Horizontal Gene Transfer-Mediated Evolution of the CRISPR-Cas System in the Mycobacterium tuberculosis Complex
Published in mSystems (01-02-2021)“…ABSTRACT Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) genes are conserved genetic elements in many…”
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Crowd sourcing a new paradigm for interactome driven drug target identification in Mycobacterium tuberculosis
Published in PloS one (11-07-2012)“…A decade since the availability of Mycobacterium tuberculosis (Mtb) genome sequence, no promising drug has seen the light of the day. This not only indicates…”
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Integration Host Factor of Mycobacterium tuberculosis, mIHF, Compacts DNA by a Bending Mechanism. e69985
Published in PloS one (01-07-2013)“…The bacterial chromosomal DNA is folded into a compact structure called as 'nucleoid' so that the bacterial genome can be accommodated inside the cell. The…”
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