Search Results - "Monceau, Elodie"
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Structure-Guided Discovery of Selective USP7 Inhibitors with In Vivo Activity
Published in Journal of medicinal chemistry (14-11-2024)“…Inhibition of ubiquitin-specific protease 7, USP7, has been proposed as a mechanism to affect many disease processes, primarily those implicated in oncology…”
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Abstract 1276: Identification of S65487/VOB560 as a potent and selective intravenous 2nd-generation BCL-2 inhibitor active in wild-type and clinical mutants resistant to Venetoclax
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract The B-cell Lymphoma 2 (BCL-2) gene family encodes pro-apoptotic and anti-apoptotic proteins that are key regulators of the apoptotic process…”
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Humanization of the mouse mammary gland by replacement of the luminal layer with genetically engineered preneoplastic human cells
Published in Breast cancer research : BCR (20-12-2014)“…The cell of origin for estrogen receptor α-positive (ERα+) breast cancer is probably a luminal stem cell in the terminal duct lobular units. To model these…”
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Erratum to: Humanization of the mouse mammary gland by replacement of the luminal layer with genetically engineered preneoplastic human cells
Published in Breast cancer research : BCR (16-09-2015)“…Due to a typesetting error, the labelling was changed and the figures in this article [1] were presented in the order 2, 4, 10, 6, 1, 3, 5, 7, 8, 9, 11, 12,…”
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Validation of a yeast functional assay for p53 mutations using clonal sequencing
Published in The Journal of pathology (01-12-2013)“…We have previously tested biopsies from 1469 breast tumours with a p53 functional assay in the context of a prospective clinical trial (EORTC 10994/BIG 1–00)…”
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