Search Results - "Monaghan, Sara A"

Immunomodulatory drugs downregulate IKZF1 leading to expansion of hematopoietic progenitors with concomitant block of megakaryocytic maturation by Liu, Ailing, Li, Shirong, Donnenberg, Vera, Fu, Jing, Gollin, Susanne M, Ma, Huihui, Lu, Caisheng, Stolz, Donna B, Mapara, Markus Y, Monaghan, Sara A, Lentzsch, Suzanne

“…The immunomodulatory drugs, lenalidomide and pomalidomide yield high response rates in multiple myeloma patients, but are associated with a high rate of…”
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Immunomodulatory derivatives induce PU.1 down-regulation, myeloid maturation arrest, and neutropenia by Pal, Rekha, Monaghan, Sara A., Hassett, Andrea Cortese, Mapara, Markus Y., Schafer, Peter, Roodman, G. David, Ragni, Margaret V., Moscinski, Lynn, List, Alan, Lentzsch, Suzanne

“…The immunomodulatory drugs (IMiDs) lenalidomide and pomalidomide yield high response rates in patients with multiple myeloma, but the use of IMiDs in multiple…”
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Venetoclax in a Patient with a Blastic Plasmacytoid Dendritic-Cell Neoplasm by Agha, Mounzer E, Monaghan, Sara A, Swerdlow, Steven H

“…A patient with a rare, aggressive, blastic plasmacytoid dendritic-cell neoplasm had tumor cells overexpressing BCL2 and had a response with a durable remission…”
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IRF8 Demonstrates Positivity in a Significant Subset of Histiocytic and Dendritic Cell Neoplasms by Patwardhan, Pranav P., Bailey, Nathanael G., Monaghan, Sara A., Singhi, Aatur D., Aggarwal, Nidhi, Djokic, Miroslav, Moore, Erika M., Rea, Bryan

“…Histiocytic and dendritic cell neoplasms, especially histiocytic sarcoma, can show morphologic and phenotypic overlap with immature monocytic neoplasms. IRF8…”
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Validation of independent prognostic significance of blast count in a large cohort of MDS patients by Al Amri, Raniah, Baloda, Vandana, Monaghan, Sara A., Rosado, Flavia G., Moore, Erika M., Rea, Bryan, Djokic, Miroslav, Aggarwal, Nidhi, Yatsenko, Svetlana A., Bailey, Nathanael G.

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IMiD immunomodulatory compounds block C/EBPβ translation through eIF4E down-regulation resulting in inhibition of MM by Li, Shirong, Pal, Rekha, Monaghan, Sara A., Schafer, Peter, Ouyang, Hongjiao, Mapara, Markus, Galson, Deborah L., Lentzsch, Suzanne

“…Immunomodulatory derivatives of thalidomide (IMiD compounds), such as pomalidomide and lenalidomide, are highly active in multiple myeloma (MM) treatment…”
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Distinct pathologic feature of myeloid neoplasm with t(v;11p15); NUP98 rearrangement by Lauw, Marietya I.S., Qi, Zhongxia, Eversmeyer, Lauren, Prakash, Sonam, Wen, Kwun Wah, Yu, Jingwei, Monaghan, Sara A., Aggarwal, Nidhi, Wang, Linlin

“…Chromosome rearrangements involving NUP98 at 11p15 are rare but recurring abnormalities in acute myeloid leukemia (AML). Here we described 12 cases of myeloid…”
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Harmonization of Training, Training Requirements, Board Certification, and Practice of Hematopathology by Swerdlow, Steven H, Monaghan, Sara A, Douglas, Aaron R, Johnson, Kristen, Johnson, Rebecca L

“…Abstract Objectives Hematopathology (HP) is a rapidly changing field with insufficient data to provide guidance to program directors (PDs), the Accreditation…”
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A Machine Learning Approach to the Classification of Acute Leukemias and Distinction From Nonneoplastic Cytopenias Using Flow Cytometry Data by Monaghan, Sara A, Li, Jeng-Lin, Liu, Yen-Chun, Ko, Ming-Ya, Boyiadzis, Michael, Chang, Ting-Yu, Wang, Yu-Fen, Lee, Chi-Chun, Swerdlow, Steven H, Ko, Bor-Sheng

“…Flow cytometry (FC) is critical for the diagnosis and monitoring of hematologic malignancies. Machine learning (ML) methods rapidly classify multidimensional…”
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Flow cytometry assay modifications: Recommendations for method validation based on CLSI H62 guidelines by Monaghan, Sara A, Eck, Steven, Bunting, Silvia, Dong, Xiangyang X, Durso, Robert J, Gonneau, Christele, Hays, Amanda, Illingworth, Andrea, League, Stacy C, Linskens, Eleni, McCausland, Megan, McCloskey, Thomas W, Rolf, Nina, Shi, Min, Wallace, Paul K, Litwin, Virginia, Kern, Wolfgang, Deeb, George, Nash, Veronica, Olteanu, Horatiu

“…The Clinical and Laboratory Standards Institute (CLSI) H62-Validation of Assays Performed by Flow Cytometry guideline, released in 2021, provides…”
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A Chunking-for-Pooling Strategy for Cytometric Representation Learning for Automatic Hematologic Malignancy Classification by Li, Jeng-Lin, Lin, Yun-Chun, Wang, Yu-Fen, Monaghan, Sara A., Ko, Bor-Sheng, Lee, Chi-Chun

“…Differentiating types of hematologic malignancies is vital to determine therapeutic strategies for the newly diagnosed patients. Flow cytometry (FC) can be…”
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Cytogenetic and Cytogenomic Microarray Characterization of Chromothripsis in Chromosome 8 Affecting MOZ/NCOA2 (TIF2), FGFR1, RUNX1T1, and RUNX1 in a Pediatric Acute Myeloid Leukemia by Koduru, Prasad R, Wilson, Kathleen, Wen, Jiadi, Garcia, Rolando, Patel, Sangeeta, Monaghan, Sara A

“…Concurrent perturbations in different driver genes have been reported primarily in lymphoma. In acute myeloid leukemia (AML), cases with concurrent alterations…”
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Does Taking the Fellowship In-Service Hematopathology Examination and Performance Relate to Success on the American Board of Pathology Hematology Examination? by Monaghan, Sara A., Felgar, Raymond E., Kelly, Melissa A., Ali, Asma M., Anastasi, John, Bellara, Aarti P., Rinder, Henry M., Sargent, Rachel L., Wagner, Jay, Swerdlow, Steven H., Johnson, Rebecca L.

“…Objectives: The biannual Fellow In-Service Hematopathology Examination (FISHE) assesses knowledge in five content areas. We examined the relationship between…”
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Zinc-induced copper deficiency: a report of three cases initially recognized on bone marrow examination by Willis, Monte S, Monaghan, Sara A, Miller, Michael L, McKenna, Robert W, Perkins, Wiley D, Levinson, Barry S, Bhushan, Vikas, Kroft, Steven H

“…Copper deficiency is a rare cause of sideroblastic anemia and neutropenia that often is not suspected clinically. The morphologic findings in bone marrow,…”
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Altered neutrophil maturation patterns that limit identification of myelodysplastic syndromes by Monaghan, Sara A., Surti, Urvashi, Doty, Ketah, Craig, Fiona E.

“…Background: Altered neutrophil maturation patterns have been reported useful for identification of myelodysplastic syndromes (MDS). Methods: Neutrophil…”
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Longitudinal bone marrow evaluations for myelodysplasia in patients with myeloma before and after treatment with lenalidomide by Monaghan, Sara A., Dai, Lijun, Mapara, Markus Y., Normolle, Daniel P., Gollin, Susanne M., Lentzsch, Suzanne

“…Abstract Lenalidomide (LEN) treatment in multiple myeloma (MM) results in a superior outcome. However, there is concern for increased myelodysplastic…”
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Toxoplasmosis in a post-transplant bronchoalveolar lavage: A case report by Monaco, Sara E., Monaghan, Sara A., Stamm, Jason A., Khalbuss, Walid E., Nichols, Larry, Pantanowitz, Liron

“…Toxoplasma gondii usually causes an asymptomatic and then latent infection in human adults; however, a potentially fatal disseminated form can occur in…”
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ZAP‐70 and Bcl‐2 expression in B lymphoblastic leukemia cells and hematogones by Craig, Fiona E., Monaghan, Sara A., Surti, Urvashi, Swerdlow, Steven H.

“…Background: Flow cytometric immunophenotyping has an established role in the diagnosis and monitoring of B‐lymphoblastic leukemia (B‐LL). However, the search…”
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Machine Learning-Facilitated Cross-Panel Automatic Classification at Both Sample and Cell Level in Acute Myeloid Leukemia by Wang, Yu-Fen, Li, Guo-Hung, Hanson, Joseph R., Tario Jr, Joseph D., Monaghan, Sara A., Ko, Bor-Sheng, Wallace, Paul K., Fu, Kai, Qian, Yu

“…Introduction Flow cytometry (FC) immunophenotyping is essential for accurate and prompt diagnosis of acute myeloid leukemia (AML), with up to 95% of AML…”
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Pan B‐cell markers are not redundant in analysis of chronic lymphocytic leukemia (CLL) by Monaghan, Sara A., Peterson, LoAnn C., James, Cathy, Marszalek, Laura, Khoong, Adela, Bachta, Dina J., Karpus, William J., Goolsby, Charles L.

“…Background The classic immunophenotype for chronic lymphocytic leukemia (CLL) is CD19+, restricted dim surface expression of kappa or lambda light chain, CD5+,…”
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